Schaetzung der Verkehrsbeziehungen bei unvollstaendiger Information und deren Anwendung bei der Verkehrssteuerung

Available from TIB Hannover: F02B909 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Immunotoxic effect of arsenic trioxide on <i>Caenorhabditis elegans</i>

<div><p>A <i>Pseudomonas aeruginosa</i>–<i>Caenorhabditis elegans</i> pathogenesis model was utilized to assess immunotoxic effects of arsenic trioxide (As₂O₃). After 2 h of As₂O₃ exposure, 500 µmol L⁻¹ and 1 mmol L⁻¹ As₂O₃ treatment significantly decreased median survivals of <i>C. elegans</i> (10 h after L4/adult molt). However, 2 h of As₂O₃ exposure caused no significant changes in the survivals rates of <i>C. elegans</i> (2 h after L4/adult molt). Notably, a significant dose-related immunoenhancement was observed in <i>C. elegans</i> (2 h after L4/adult molt) after 12 h of arsenite exposure.</p></div

Map of the sampling locations in the Yangtze River estuary.

<p>Map of the sampling locations in the Yangtze River estuary.</p

Mutagenic activity of nine sediment extracts from Yangtze River estuary.

<p>Mutagenic measured by the Ames fluctuation assay using both TA98 and TA100 bacteria strain with and without bioactivation enzymes (S9). TA100 with or without S9 is not shown because no mutagenic effects were observed in any of the samples. Data are shown as maximum induction factor (IF_max) as the highest IF score of a particular sample within the dose-response curve. Multiple symbols indicate different significant levels relative to the negative control (NC): *<i>p</i><0.05, **<i>p</i><0.01.</p

Mutagenic activity of three fractions of samples Y2, Y7, Y8 and Y9.

<p>Mutagenicity measured by the Ames fluctuation assay using TA98 bacteria with and without bioactivation enzymes (S9). Mutagenic activity is expressed as maximum induction factor within the dose-response curve.</p

Content of total organic carbon (TOC) (%) and concentrations of the 16 US EPA-polycyclic aromatic hydrocarbons (PAHs) (ng/g dw) in sediment samples from the Yangtze River estuary.

<p>Note: The data of PAHs were obtained from Liu et al. (2014). n.d. = not detectable or below the detection limit.</p><p>Content of total organic carbon (TOC) (%) and concentrations of the 16 US EPA-polycyclic aromatic hydrocarbons (PAHs) (ng/g dw) in sediment samples from the Yangtze River estuary.</p

Additional file 1 of Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying blaNDM−1 gene: imipenem exposure results in sustained resistance memory of strains in vitro

Additional files 1: Table S1. The resistance of 20 clinical isolates to 17 antibiotics.   Additional files 2: Table S2. Transmission of drug resistance phenotype of imipenem exposed strains in subculture cells.   Additional files 3: Fig. S1. The electropherogram map of blaNDM−1-pET28a (+) plasmid.   Additional files 4: Fig. S2. The electropherogram map of blaNDM−1 gene amplified from blaNDM−1-pET28a (+) plasmid

The contribution of Chem-TEQs of PAHs to Bio-TEQs.

<p>The total biological response of the crude extracts in the EROD assay with RTL-W1 cells are expressed as bio-TEQs. The chem-TEQs of the 16 measured EPA PAHs were calculated by multiplying compounds concentrations and relative equivalency potencies and are given in pg/g dw. Numbers in percent indicated the calculated contribution of these PAHs to the EROD induction in each crude extract.</p

AhR-mediated activities of crude and multilayer fractions of sediment extracts from the Yangtze River estuary.

<p>The results are based on EROD inductions with RTL-W1 cells and presented as bio-TEQs. F1 contains non-polar paraffinic components. F2 contains weakly and moderately polar components. F3 contains highly polar components. The numbers in percentage were calculated as (F1+F2+F3–CE)/CE×100%. The difference between the combined F1 to F3 and the induced crude extracts induction is given. Bio-TEQs are given as means of <i>n</i> = 3 independent experiments. CE, crude extracts.</p

AhR-mediated activity of sediment extracts from the Yangtze River estuary.

<p>The values as determined by the EROD assay with RTL-W1 cells are expressed as biological toxicity equivalents (Bio-TEQ; pg/g dw). Data are given as means of 3 replicates ± SD.</p