Table_2_Is hysterectomy associated with kidney cancer risk? A meta-analysis of cohort studies.docx

IntroductionEmerging evidence have suggested a potential relationship between hysterectomy and risk of kidney cancer with inconsistent results. We aimed to investigate the association of hysterectomy with kidney cancer risk based on a meta-analysis of all available cohort studies.MethodsA comprehensive literature search was performed in the PubMed and Embase database, covering all the papers published by September 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) were estimated using a DerSimonian and Laird random effects model.ResultsOverall, our meta-analysis included 10 cohorts from 9 studies with approximately 240 million participants. The pooled RR with its 95% CI showed a significantly positive association between hysterectomy and risk of kidney cancer (RR 1.30, 95% CI 1.19-1.41). No obvious heterogeneity was observed across the studies (P = 0.206 for heterogeneity; I2 = 25.9%).ConclusionFindings from this meta-analysis of cohort studies indicated that hysterectomy was positively associated with subsequent kidney cancer risk. Further large prospective studies with long-term follow-up are warranted to verify these findings.</p

Table_1_Is hysterectomy associated with kidney cancer risk? A meta-analysis of cohort studies.docx

IntroductionEmerging evidence have suggested a potential relationship between hysterectomy and risk of kidney cancer with inconsistent results. We aimed to investigate the association of hysterectomy with kidney cancer risk based on a meta-analysis of all available cohort studies.MethodsA comprehensive literature search was performed in the PubMed and Embase database, covering all the papers published by September 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) were estimated using a DerSimonian and Laird random effects model.ResultsOverall, our meta-analysis included 10 cohorts from 9 studies with approximately 240 million participants. The pooled RR with its 95% CI showed a significantly positive association between hysterectomy and risk of kidney cancer (RR 1.30, 95% CI 1.19-1.41). No obvious heterogeneity was observed across the studies (P = 0.206 for heterogeneity; I2 = 25.9%).ConclusionFindings from this meta-analysis of cohort studies indicated that hysterectomy was positively associated with subsequent kidney cancer risk. Further large prospective studies with long-term follow-up are warranted to verify these findings.</p

A flow chart from Android APP program.

<p>A flow chart from Android APP program.</p

The server program workflow.

<p>The server program workflow.</p

End-to-end delay.

<p>End-to-end delay.</p

ZigBee network routing layout after simulation.

<p>ZigBee network routing layout after simulation.</p

The performance testing of the server.

<p>The performance testing of the server.</p

The process of ZigBee Ad-hoc network.

<p>The process of ZigBee Ad-hoc network.</p

miR-194 is in accordance with Sox5 in osteoarthritis.

<p>(A) Primary chondrocyte was treated by IL-1βfor 24 h, DMSO was added as control group, qRT-PCR showed that miR-194 was up-regulated, The relative gene expression alteration was demonstrated by percentage increase and (B)Western-blotting Assay showed that Sox5 was down-regulated compared with control group. Three independent cell culture experiments were done.</p

GA-PSOA computational flow chart.

<p>GA-PSOA computational flow chart.</p