Preparation of a Novel Formaldehyde-Free Impregnated Decorative Paper Containing MnO₂ Nanoparticles for Highly Efficient Formaldehyde Removal

The loading of catalytic manganese dioxide (MnO2) nanoparticles onto an impregnated decorative paper has been an effective method for the removal of indoor formaldehyde (HCHO) pollutants. However, its preparation can present numerous challenges, including instability in dipping emulsions and leaching. In this investigation, a novel and stable formaldehyde-free polyacrylate dipping emulsion containing MnO2 particles was prepared and then back-coated on a decorative paper. To improve the dispersion and fixation, the MnO2 was modified with silane. HCHO can undergo physical adsorption on the cellulosic fibers present in the paper, while it can also undergo chemical degradation into CO2 within the MnO2 groups. The silane not only enhanced the interfacial adhesion to a polyacrylate resin but also increased the interlayer distance, thereby creating a larger space for HCHO absorption. The impregnated decorative paper back-coated with 10 wt % of silane-modified MnO2 exhibited a removal efficiency of approximately 90% for HCHO at 20 °C. The removal rate further improved to approximately 100% when the temperature was increased to 60 °C. Moreover, it is worth noting that the release of volatile organic compounds was exceptionally minimal. Additionally, the particleboard bonded with this impregnated decorative paper exhibited an extremely low emission of HCHO, with a value that approached 0 mg·L–1. Furthermore, the bonding strength of the surface remained unaffected. Therefore, this study provides a simple and eco-friendly method for effectively removing HCHO, which can enhance indoor air quality

Spearman's rank correlation coefficient (r_s) and <i>P</i> values between Hcy and clinical variables, and between CRP and clinical variables.

<p>* <i>P</i><0.05,</p><p>** <i>P</i><0.01,</p><p>*** <i>P</i><0.001.</p><p>Abbreviations: r_s, Spearman's rank correlation coefficient; H&Y, the modified Hoehn and Yahr staging scale; MMSE, mini-mental state examination.</p

Comparison of age, BMI, Hcy, CRP, UPDRS (III), MMSE, and NMSS between PD and VP.

<p>* <i>P</i><0.01.</p><p>Abbreviations: SD, Standard deviation; BMI, Body Mass Index; MMSE, mini-mental state examination; UPDRS III, the unified Parkinson's disease rating scale part III; and NMSS, non-motor symptoms scale for Parkinson's disease (range of possible scores from 0 to 360).</p

Demographic, motor, and non-motor parameters.

<p>Abbreviations: SD, Standard deviation; BMI, Body Mass Index; MMSE, mini-mental state examination; UPDRS III, the unified Parkinson's disease rating scale part III; H&Y, the modified Hoehn and Yahr staging scale; and NMSS, non-motor symptoms scale for Parkinson's disease (range of possible scores from 0 to 360).</p

Neutrophil Nanodecoys Inhibit Tumor Metastasis by Blocking the Interaction between Tumor Cells and Neutrophils

Cancer metastasis is the main cause of cancer-related deaths and involves the interaction between tumor cells and neutrophils. In this study, we developed activated neutrophil membrane-coated nanoparticles (aNEM NPs) as nanodecoys to block neutrophil-mediated cancer metastasis. The aNEM NPs were fabricated by cloaking poly(lactic acid) nanoparticles with membranes derived from activated neutrophils and inherited the functional proteins of activated neutrophils. We demonstrated that aNEM NPs could interfere with the recruitment of neutrophils to the primary tumor and premetastatic niches, inhibit the adhesion of neutrophils to tumor vascular endothelium and circulating tumor cells (CTCs), and disrupt the formation of CTC–neutrophil clusters in vitro and in vivo. In 4T1-bearing mice, aNEM NPs could effectively reduce breast cancer metastasis to various organs in mice. Our results suggest that aNEM NPs are a promising nanomedicine for preventing or treating cancer metastasis by acting as neutrophil nanodecoys

Spearman's rank correlation coefficient (r_s) and <i>P</i> values between UPDRS III and clinical variables, and between H&Y and clinical variables.

<p>* <i>P</i><0.05,</p><p>** <i>P</i><0.001.</p><p>Abbreviations: r_s, Spearman's rank correlation coefficient; H&Y, the modified Hoehn and Yahr staging scale; UPDRS III, the unified Parkinson's disease rating scale part III; MMSE, mini-mental state examination; NMSS, non-motor symptoms scale for Parkinson's disease.</p

Comparison of Hcy and CRP among patients with PD and VP.

<p>* <i>P</i><0.01</p