2 research outputs found
Microwave-Assisted Topochemical Conversion of Layered Titanate Nanosheets to {010}-Faceted Anatase Nanocrystals for High Performance Photocatalysts and Dye-Sensitized Solar Cells
The {010}-faceted anatase nanocrystals
with controllable crystal
size and morphology were synthesized by microwave hydrothermal treatment
of layered titanate nanosheet solutions. The nanostructures and formation
reaction mechanism of TiO<sub>2</sub> nanocrystals were investigated
using X-ray diffraction, field emission scanning electron microscopy,
transmission electron microscopy, and selected-area electron diffraction.
Their photocatalytic behavior and dye-sensitized solar cell (DSSC)
performance were studied and compared with [111]-faceted anatase nanocrystals
and anatase nanocrystals without a specific facet on the surface.
There are two kinds of reactions in the formation process of the anatase
nanocrystals. One is an in situ topochemical conversion reaction of
layered titanate structure to anatase structure, and another is the
dissolution–deposition reaction on the particle surface. The
microwave hydrothermal process is suitable to control the structural
conversion reaction for uniform the crystal size and morphology due
to its uniform heating mechanism. The UV–visible spectrum results
revealed that the bandgap of the TiO<sub>2</sub> nanocrystals was
enhanced in the order of nanocrystal without specific facet < [111]-faceted
nanocrystal < {010}-faceted nanocrystal, which corresponded to
their photocatalytic activities. The DSSC performance also was enhanced
in the same order, suggesting that the {010}-faceted nanocrystals
are promising for the high performance DSSCs
Photothermal Ablation of in Situ Renal Tumor by PEG-IR780-C13 Micelles and Near-Infrared Irradiation
PEG-IR780-C13 micelles have been
demonstrated to be a novel photothermal
agent with tumor-targeting property. This study was designed to explore
the feasibility of applying PEG-IR780-C13 micelles and near-infrared
(NIR) irradiation for thermal ablation of renal tumor by using an
in situ tumor model. In addition, the potential thermal injury to
normal renal tissue was evaluated. PEG-IR780-C13 micelles were intended
to accumulate in renal tumor after systemic delivery. In vitro results
revealed that PEG-IR780-C13 micelles were uptaken by RENCA cells mainly
through caveola-mediated endocytosis and mainly distributed in late
endosomes and lysosomes. Upon NIR irradiation, PEG-IR780-C13 micelles
generated heat effectively both in vitro and in vivo, exhibiting a
promising photothermal therapeutic property. The photothermal effect
of PEG-IR780-C13 micelles could effectively destroy RENCA cells in
vitro and adequately inhibit growth of in situ renal tumor in vivo.
Meanwhile, PEG-IR780-C13 micelles mediated photothermal therapy (PTT)
resulting in only limited injury to normal renal tissue surrounding
tumor sites. Our data indicated that PEG-IR780-C13 micelles mediating
PTT could generate tumor-specific heat for destruction of renal tumor
in a minimally invasive way, providing a novel strategy for thermal
ablation of renal tumor