Obstetric Thromboprophylaxis: The Swedish Guidelines

Obstetric thromboprophylaxis is difficult. Since 10 years Swedish obstetricians have used a combined risk estimation model and recommendations concerning to whom, at what dose, when, and for how long thromboprophylaxis is to be administrated based on a weighted risk score. In this paper we describe the background and validation of the Swedish guidelines for obstetric thromboprophylaxis in women with moderate-high risk of VTE, that is, at similar or higher risk as the antepartum risk among women with history of thrombosis. The risk score is based on major risk factors (i.e., 5-fold increased risk of thromboembolism). We present data on the efficacy of the model, the cost-effectiveness, and the lifestyle advice that is given. We believe that the Swedish guidelines for obstetric thromboprophylaxis aid clinicians in providing women at increased risk of VTE with effective and appropriate thromboprophylaxis, thus avoiding both over- and under-treatment

Dynamical Friction on Star Clusters near the Galactic Center

Numerical simulations of the dynamical friction suffered by a star cluster near the Galactic center have been performed with a parallelized tree code. Gerhard (2001) has suggested that dynamical friction, which causes a cluster to lose orbital energy and spiral in towards the galactic center, may explain the presence of a cluster of very young stars in the central parsec, where star formation might be prohibitively difficult owing to strong tidal forces. The clusters modeled in our simulations have an initial total mass of 10^5-10^6 Msun and initial galactocentric radii of 2.5-30 pc. We have identified a few simulations in which dynamical friction indeed brings a cluster to the central parsec, although this is only possible if the cluster is either very massive (~10^6 Msun), or is formed near the central parsec (<~ 5 pc). In both cases, the cluster should have an initially very dense core (> 10^6 Msun pc-3). The initial core collapse and segregation of massive stars into the cluster core, which typically happens on a much shorter time scale than that characterizing the dynamical inspiral of the cluster toward the Galactic center, can provide the requisite high density. Furthermore, because it is the cluster core which is most likely to survive the cluster disintegration during its journey inwards, this can help account for the observed distribution of presumably massive HeI stars in the central parsec.Comment: Accepted for publication in Ap

5 year Global 3-mm VLBI survey of Gamma-ray active blazars

The Global mm-VLBI Array (GMVA) is a network of 14 3\,mm and 7\,mm capable telescopes spanning Europe and the United States, with planned extensions to Asia. The array is capable of sensitive maps with angular resolution often exceeding 50\,$\mu$as. Using the GMVA, a large sample of prominent $\gamma$-ray blazars have been observed approximately 6 monthly from later 2008 until now. Combining 3\,mm maps from the GMVA with near-in-time 7\,mm maps from the VLBA-BU-BLAZAR program and 2\,cm maps from the MOJAVE program, we determine the sub-pc morphology and high frequency spectral structure of $\gamma$-ray blazars. The magnetic field strength can be estimated at different locations along the jet under the assumption of equipartition between magnetic field and relativistic particle energies. Making assumptions on the jet magnetic field configuration (e.g. poloidal or toroidal), we can estimate the separation of the mm-wave "core" and the jet base, and estimate the strength of the magnetic field there. The results of this analysis show that on average, the magnetic field strength decreases with a power-law $B \propto r^{-n}$, $n=0.3 \pm 0.2$. This suggests that on average, the mm-wave "core" is $\sim 1-3$\,pc downstream of the de-projected jet apex and that the magnetic field strength is of the order $B_{\rm{apex}} \sim 5-20$\,kG, broadly consistent with the predictions of magnetic jet launching (e.g. via magnetically arrested disks (MAD)).Comment: 6 pages, 1 figur

The slope of the black-hole mass versus velocity dispersion correlation

Observations of nearby galaxies reveal a strong correlation between the mass of the central dark object M and the velocity dispersion sigma of the host galaxy, of the form log(M/M_sun) = a + b*log(sigma/sigma_0); however, published estimates of the slope b span a wide range (3.75 to 5.3). Merritt & Ferrarese have argued that low slopes (<4) arise because of neglect of random measurement errors in the dispersions and an incorrect choice for the dispersion of the Milky Way Galaxy. We show that these explanations account for at most a small part of the slope range. Instead, the range of slopes arises mostly because of systematic differences in the velocity dispersions used by different groups for the same galaxies. The origin of these differences remains unclear, but we suggest that one significant component of the difference results from Ferrarese & Merritt's extrapolation of central velocity dispersions to r_e/8 (r_e is the effective radius) using an empirical formula. Another component may arise from dispersion-dependent systematic errors in the measurements. A new determination of the slope using 31 galaxies yields b=4.02 +/- 0.32, a=8.13 +/- 0.06, for sigma_0=200 km/s. The M-sigma relation has an intrinsic dispersion in log M that is no larger than 0.3 dex. In an Appendix, we present a simple model for the velocity-dispersion profile of the Galactic bulge.Comment: 37 pages, 9 figure

The circumstellar envelope around the S-type AGB star W Aql Effects of an eccentric binary orbit

The CO(J=3-2) emission from the CSE of the binary S-type AGB star W Aql has been observed at subarcsecond resolution using ALMA. The aim of this paper is to investigate the wind properties of the AGB star and to analyse how the known companion has shaped the CSE. The average mass-loss rate during the creation of the detected CSE is estimated through modelling, using the ALMA brightness distribution and previously published single-dish measurements as observational constraints. The ALMA observations are presented and compared to the results from a 3D smoothed particle hydrodynamics (SPH) binary interaction model with the same properties as the W Aql system and with two different orbital eccentricities. Three-dimensional radiative transfer modelling is performed and the response of the interferometer is modelled and discussed. The estimated average mass-loss rate of W~Aql agrees with previous results. The size of the emitting region is consistent with photodissociation models. The CO(J=3-2) emission is dominated by a smooth component overlayed with two weak arc patterns with different separations. The larger pattern is predicted by the binary interaction model with separations of 10" and therefore likely due to the known companion. It is consistent with a binary orbit with low eccentricity. The smaller separation pattern is asymmetric and coincides with the dust distribution, but the separation timescale (200 yrs) is not consistent with any known process of the system. The separation of the known companions of the system is large enough to not have a very strong effect on the circumstellar morphology. The density contrast across the envelope of a binary with an even larger separation will not be easily detectable, even with ALMA, unless the orbit is strongly asymmetric or the AGB star has a much larger mass-loss rate.Comment: 10 pages, 8 figure

N-Body Simulations of Compact Young Clusters near the Galactic Center

We investigate the dynamical evolution of compact young star clusters (CYCs) near the Galactic center (GC) using Aarseth's Nbody6 codes. The relatively small number of stars in the cluster (5,000-20,000) makes real-number N-body simulations for these clusters feasible on current workstations. Using Fokker-Planck (F-P) models, Kim, Morris, & Lee (1999) have made a survey of cluster lifetimes for various initial conditions, and have found that clusters with a mass <~ 2x10^4 Msun evaporate in ~10 Myr. These results were, however, to be confirmed by N-body simulations because some extreme cluster conditions, such as strong tidal forces and a large stellar mass range participating in the dynamical evolution, might violate assumptions made in F-P models. Here we find that, in most cases, the CYC lifetimes of previous F-P calculations are 5-30% shorter than those from the present N-body simulations. The comparison of projected number density profiles and stellar mass functions between N-body simulations and HST/NICMOS observations by Figer et al. (1999) suggests that the current tidal radius of the Arches cluster is ~1.0 pc, and the following parameters for the initial conditions of that cluster: total mass of 2x10^4 Msun and mass function slope for intermediate-to-massive stars of 1.75 (the Salpeter function has 2.35). We also find that the lower stellar mass limit, the presence of primordial binaries, the amount of initial mass segregation, and the choice of initial density profile (King or Plummer models) do not significantly affect the dynamical evolution of CYCs.Comment: 20 pages including 6 figures, To appear in ApJ, Dec 20 issu