Budgeting for Growth and Prosperity: A Long-Term Plan to Balance the Budget, Grow the Economy, and Strengthen the Middle Class

Proposes reducing the deficit by investing in education, infrastructure, and technology; spending more efficiently; bolstering the social safety net; containing healthcare costs; simplifying the tax code; and raising gas and financial transaction taxes

Excitations in disordered bosonic optical lattices

Spectral excitations of ultracold gases of bosonic atoms trapped in one dimensional optical lattices with disorder are investigated by means of the variational cluster approach applied to the Bose-Hubbard model. In particular, qualitatively different disorder distributions typically employed in experiments are considered. The computed spectra exhibit a strong dependence on both the shape of the disorder distribution and the disorder strength. We compare alternative results for the Mott gap obtained from its formal definition and from the minimum peak distance, which is the quantity available from experiments.Comment: 8 pages, 7 figures, version as publishe

Drainage and retention of water in small drainage cavities : experimental assessment

Water that enters the drainage cavity of a rain screen wall assembly through deficiencies in the cladding will either be drained or retained by absorption or adhesion on the drainage surfaces. The objective of this study is to gain insight into the different factors that affect the quantity of water drained or retained in a drainage cavity. Drainage tests have been conducted for water flowing between two vertical polycarbonate plates with different gap widths to determine the effect on the drainage rate. Tests showed that even small cavities with a width of 1 mm can already drain more water than the amount that would enter the cavity during a rain event. Experiments were performed to determine the contact angle of water on a range of different sheathing materials such as asphalt saturated building paper, spun-bonded polyethylene wrap and cross-woven polyolefin wrap by the use of an optical goniometer. Drainage tests have been conducted for different combinations of these materials to quantify the effect of surface energy on the drainage rate. A larger contact angle results in a smaller quantity of water retained during the drainage test. These tests result in a retained portion of water and a drainage rate for different combinations of materials. The retained portion of water may be considered as a moisture load applied to the outer-most layer of the wall assembly’s back-up wall in hygrothermal simulations

Statistical methods for tissue array images - algorithmic scoring and co-training

Recent advances in tissue microarray technology have allowed immunohistochemistry to become a powerful medium-to-high throughput analysis tool, particularly for the validation of diagnostic and prognostic biomarkers. However, as study size grows, the manual evaluation of these assays becomes a prohibitive limitation; it vastly reduces throughput and greatly increases variability and expense. We propose an algorithm - Tissue Array Co-Occurrence Matrix Analysis (TACOMA) - for quantifying cellular phenotypes based on textural regularity summarized by local inter-pixel relationships. The algorithm can be easily trained for any staining pattern, is absent of sensitive tuning parameters and has the ability to report salient pixels in an image that contribute to its score. Pathologists' input via informative training patches is an important aspect of the algorithm that allows the training for any specific marker or cell type. With co-training, the error rate of TACOMA can be reduced substantially for a very small training sample (e.g., with size 30). We give theoretical insights into the success of co-training via thinning of the feature set in a high-dimensional setting when there is "sufficient" redundancy among the features. TACOMA is flexible, transparent and provides a scoring process that can be evaluated with clarity and confidence. In a study based on an estrogen receptor (ER) marker, we show that TACOMA is comparable to, or outperforms, pathologists' performance in terms of accuracy and repeatability.Comment: Published in at http://dx.doi.org/10.1214/12-AOAS543 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org