Copy number variations in absence epilepsy

Poster for British Paediatric Neurology Association Annual Conference 201

Summary of effects found comparing three groups (normal controls, patients, relatives).

<p>For details of Bonferroni correction see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0110136#s2" target="_blank">Methods</a>. Uncorr  =  uncorrected.</p><p>Summary of effects found comparing three groups (normal controls, patients, relatives).</p

Clinical characteristics of the patients.

<p>CAE childhood absence epilepsy, GTCS generalised tonic clonic seizures only, JAE juvenile absence epilepsy, JME juvenile myoclonic epilepsy, MJ myoclonic jerks, Abs absences, Ph + Photosensitivity; GSW generalised spike and wave, PSW polyspike and wave; SF Seizure Free; N/a not available.</p><p>Clinical characteristics of the patients.</p

An abnormal EEG network topology is an endophenotype of IGE, present in patients and first-degree relatives.

<p>Group means +/− standard error of the mean are shown for: (A) mean degree <i>K</i>, (B) mean degree variance <i>D</i>, (C) clustering coefficient , and (D) normalised path length , in the 6–9 Hz band. Normal controls (dark blue), patients with IGE (orange), and first-degree relatives of patients with IGE (light blue). *  =  p<0.05 Bonferroni corrected compared with normal controls.</p