3,125 research outputs found
General Argyres-Douglas Theory
We construct a large class of Argyres-Douglas type theories by compactifying
six dimensional (2,0) A_N theory on a Riemann surface with irregular
singularities. We give a complete classification for the choices of Riemann
surface and the singularities. The Seiberg-Witten curve and scaling dimensions
of the operator spectrum are worked out. Three dimensional mirror theory and
the central charges a and c are also calculated for some subsets, etc. Our
results greatly enlarge the landscape of N=2 superconformal field theory and in
fact also include previous theories constructed using regular singularity on
the sphere.Comment: 55 pages, 20 figures, minor revision and typos correcte
A framework for the successful implementation of food traceability systems in China
Implementation of food traceability systems in China faces many challenges due to the scale, diversity and complexity of China’s food supply chains. This study aims to identify critical success factors specific to the implementation of traceability systems in China. Twenty-seven critical success factors were identified in the literature. Interviews with managers at four food enterprises in a pre-study helped identify success criteria
and five additional critical success factors. These critical success factors were tested through a survey of managers in eighty-three food companies. This study identifies six dimensions for critical success factors: laws, regulations and standards; government support; consumer knowledge and support; effective management and communication; top management and vendor support; and information and system quality
Weak pairwise correlations imply strongly correlated network states in a neural population
Biological networks have so many possible states that exhaustive sampling is
impossible. Successful analysis thus depends on simplifying hypotheses, but
experiments on many systems hint that complicated, higher order interactions
among large groups of elements play an important role. In the vertebrate
retina, we show that weak correlations between pairs of neurons coexist with
strongly collective behavior in the responses of ten or more neurons.
Surprisingly, we find that this collective behavior is described quantitatively
by models that capture the observed pairwise correlations but assume no higher
order interactions. These maximum entropy models are equivalent to Ising
models, and predict that larger networks are completely dominated by
correlation effects. This suggests that the neural code has associative or
error-correcting properties, and we provide preliminary evidence for such
behavior. As a first test for the generality of these ideas, we show that
similar results are obtained from networks of cultured cortical neurons.Comment: Full account of work presented at the conference on Computational and
Systems Neuroscience (COSYNE), 17-20 March 2005, in Salt Lake City, Utah
(http://cosyne.org
Progress Toward a Human CD4/CCR5 Transgenic Rat Model for De Novo Infection by Human Immunodeficiency Virus Type 1
The development of a permissive small animal model for the study of human immunodeficiency virus type (HIV)-1 pathogenesis and the testing of antiviral strategies has been hampered by the inability of HIV-1 to infect primary rodent cells productively. In this study, we explored transgenic rats expressing the HIV-1 receptor complex as a susceptible host. Rats transgenic for human CD4 (hCD4) and the human chemokine receptor CCR5 (hCCR5) were generated that express the transgenes in CD4+ T lymphocytes, macrophages, and microglia. In ex vivo cultures, CD4+ T lymphocytes, macrophages, and microglia from hCD4/hCCR5 transgenic rats were highly susceptible to infection by HIV-1 R5 viruses leading to expression of abundant levels of early HIV-1 gene products comparable to those found in human reference cultures. Primary rat macrophages and microglia, but not lymphocytes, from double-transgenic rats could be productively infected by various recombinant and primary R5 strains of HIV-1. Moreover, after systemic challenge with HIV-1, lymphatic organs from hCD4/hCCR5 transgenic rats contained episomal 2–long terminal repeat (LTR) circles, integrated provirus, and early viral gene products, demonstrating susceptibility to HIV-1 in vivo. Transgenic rats also displayed a low-level plasma viremia early in infection. Thus, transgenic rats expressing the appropriate human receptor complex are promising candidates for a small animal model of HIV-1 infection
Semiautomated Device for Batch Extraction of Metabolites from Tissue Samples
ABSTRACT: Metabolomics has become a mainstream analytical strategy for investigating metabolism. The quality of data derived from these studies is proportional to the consistency of the sample preparation. Although considerable research has been devoted to finding optimal extraction protocols, most of the established methods require extensive sample handling. Manual sample preparation can be highly effective in the hands of skilled technicians, but an automated tool for purifying metabolites from complex biological tissues would be of obvious utility to the field. Here, we introduce the semiautomated metabolite batch extraction device (SAMBED), a new tool designed to simplify metabolomics sample preparation. We discuss SAMBED’s design and show that SAMBED-based extractions are of comparable quality to extracts produced through traditional methods (13 % mean coefficient of variation from SAMBED versus 16 % from manual extractions). Moreover, we show that aqueous SAMBED-based methods ca
Observation and study of the decay
We report the observation and study of the decay
using events
collected with the BESIII detector. Its branching fraction, including all
possible intermediate states, is measured to be
. We also report evidence for a structure,
denoted as , in the mass spectrum in the GeV/
region. Using two decay modes of the meson ( and
), a simultaneous fit to the mass spectra is
performed. Assuming the quantum numbers of the to be , its
significance is found to be 4.4, with a mass and width of MeV/ and MeV, respectively, and a
product branching fraction
. Alternatively, assuming , the
significance is 3.8, with a mass and width of MeV/ and MeV, respectively, and a product
branching fraction
. The angular distribution of
is studied and the two assumptions of the
cannot be clearly distinguished due to the limited statistics. In all
measurements the first uncertainties are statistical and the second systematic.Comment: 10 pages, 6 figures and 4 table
Observation of and confirmation of its large branching fraction
The baryonic decay is observed, and the
corresponding branching fraction is measured to be
, where the first uncertainty is statistical
and second systematic. The data sample used in this analysis was collected with
the BESIII detector operating at the BEPCII double-ring collider with
a center-of-mass energy of 4.178~GeV and an integrated luminosity of
3.19~fb. The result confirms the previous measurement by the CLEO
Collaboration and is of greatly improved precision, which may deepen our
understanding of the dynamical enhancement of the W-annihilation topology in
the charmed meson decays
Observation of and Improved Measurements of
Using a data sample corresponding to an integrated luminosity of
2.93~fb recorded by the BESIII detector at a center-of-mass energy of
GeV, we present an analysis of the decays and . By performing a partial wave
analysis, the -wave contribution to
is observed to be % with a statistical significance greater
than 10, besides the dominant -wave contribution. This is the first
observation of the -wave contribution. We measure the branching fractions
, , and . An upper limit
of is set at the 90% confidence level. We also obtain the hadronic
form factor ratios of at assuming the
single-pole dominance parameterization:
,
Evidence of a resonant structure in the cross section between 4.05 and 4.60 GeV
The cross section of the process for
center-of-mass energies from 4.05 to 4.60~GeV is measured precisely using data
samples collected with the BESIII detector operating at the BEPCII storage
ring.
Two enhancements are clearly visible in the cross section around 4.23 and
4.40~GeV.
Using several models to describe the dressed cross section yields stable
parameters for the first enhancement, which has a mass of 4228.6 \pm 4.1 \pm
6.3 \un{MeV}/c^2 and a width of 77.0 \pm 6.8 \pm 6.3 \un{MeV}, where the
first uncertainties are statistical and the second ones are systematic.
Our resonant mass is consistent with previous observations of the
state and the theoretical prediction of a molecule.
This result is the first observation of associated with an
open-charm final state.
Fits with three resonance functions with additional , ,
, , or a new resonance, do not show significant
contributions from either of these resonances. The second enhancement is not
from a single known resonance. It could contain contributions from
and other resonances, and a detailed amplitude analysis is required to better
understand this enhancement
Evidence for the decays of and
We study the hadronic decays of to the final states
and , using an annihilation
data sample of 567 pb taken at a center-of-mass energy of 4.6 GeV with
the BESIII detector at the BEPCII collider. We find evidence for the decays
and with
statistical significance of and , respectively.
Normalizing to the reference decays and
, we obtain the ratios of the branching fractions
and to be and , respectively. The upper limits at the 90\% confidence level are
set to be and . Using BESIII measurements of the
branching fractions of the reference decays, we determine
() and
(). Here, the first uncertainties are statistical and the second
systematic. The obtained branching fraction of is
consistent with the previous measurement, and the branching fraction of
is measured for the first
time.Comment: Accepted by Chin. Phys. C : Chin. Phys. C 43, 083002, (2019
- …