Task-Oriented Conversation Generation Using Heterogeneous Memory Networks

How to incorporate external knowledge into a neural dialogue model is critically important for dialogue systems to behave like real humans. To handle this problem, memory networks are usually a great choice and a promising way. However, existing memory networks do not perform well when leveraging heterogeneous information from different sources. In this paper, we propose a novel and versatile external memory networks called Heterogeneous Memory Networks (HMNs), to simultaneously utilize user utterances, dialogue history and background knowledge tuples. In our method, historical sequential dialogues are encoded and stored into the context-aware memory enhanced by gating mechanism while grounding knowledge tuples are encoded and stored into the context-free memory. During decoding, the decoder augmented with HMNs recurrently selects each word in one response utterance from these two memories and a general vocabulary. Experimental results on multiple real-world datasets show that HMNs significantly outperform the state-of-the-art data-driven task-oriented dialogue models in most domains.Comment: Accepted as a long paper at EMNLP-IJCNLP 201

MTSS: Learn from Multiple Domain Teachers and Become a Multi-domain Dialogue Expert

How to build a high-quality multi-domain dialogue system is a challenging work due to its complicated and entangled dialogue state space among each domain, which seriously limits the quality of dialogue policy, and further affects the generated response. In this paper, we propose a novel method to acquire a satisfying policy and subtly circumvent the knotty dialogue state representation problem in the multi-domain setting. Inspired by real school teaching scenarios, our method is composed of multiple domain-specific teachers and a universal student. Each individual teacher only focuses on one specific domain and learns its corresponding domain knowledge and dialogue policy based on a precisely extracted single domain dialogue state representation. Then, these domain-specific teachers impart their domain knowledge and policies to a universal student model and collectively make this student model a multi-domain dialogue expert. Experiment results show that our method reaches competitive results with SOTAs in both multi-domain and single domain setting.Comment: AAAI 2020, Spotlight Pape

Molecular Bubble and Outflow in S Mon Revealed by Multiband Datasets

We identify a molecular bubble, and study the star formation and its feedback in the S Mon region, using multiple molecular lines, young stellar objects (YSOs), and infrared data. We revisit the distance to S Mon, ~722+/-9 pc, using Gaia Data Release 3 parallaxes of the associated Class II YSOs. The bubble may be mainly driven by a massive binary system (namely 15 Mon), the primary of which is an O7V-type star. An outflow is detected in the shell of the bubble, suggesting ongoing star formation activities in the vicinity of the bubble. The total wind energy of the massive binary star is three orders of magnitude higher than the sum of the observed turbulent energy in the molecular gas and the kinetic energy of the bubble, indicating that stellar winds help to maintain the turbulence in the S Mon region and drive the bubble. We conclude that the stellar winds of massive stars have an impact on their surrounding environment.Comment: 34 pages,19 figures, 5 tables, Accepted for publication in Ap

Revisiting the Multisite Phosphorylation That Produces the M-Phase Supershift of Key Mitotic Regulators

The term M-phase supershift denotes the phosphorylation-dependent substantial increase in the apparent molecular weight of numerous proteins of varied biological functions during M-phase induction. Although the M-phase supershift of multiple key mitotic regulators has been attributed to the multisite phosphorylation catalyzed by the Cdk1/cyclin B/Cks complex, this view is challenged by multiple lines of paradoxical observations. To solve this problem, we reconstituted the M-phase supershift of Xenopus Cdc25C, Myt1, Wee1A, APC3, and Greatwall in Xenopus egg extracts and characterized the supershift-producing phosphorylations. Our results demonstrate that their M-phase supershifts are each due to simultaneous phosphorylation of a considerable portion of S/T/Y residues in a long intrinsically disordered region that is enriched in both S/T residues and S/TP motifs. Although the major mitotic kinases in Xenopus egg extracts, Cdk1, MAPK, Plx1, and RSK2, are able to phosphorylate the five mitotic regulators, they are neither sufficient nor required to produce the M-phase supershift. Accordingly, inhibition of the four major mitotic kinase activities in Xenopus oocytes did not inhibit the M-phase supershift in okadaic acid-induced oocyte maturation. These findings indicate that the M-phase supershift is produced by a previously unrecognized category of mitotic phosphorylation that likely plays important roles in M-phase induction

Distributions and Physical Properties of Molecular Clouds in the Third Galactic Quadrant: ll = [219.75, 229.75]∘^\circ and bb = [-5.25, 5.25]∘^\circ

We present the results of an unbiased $^{12}$CO/$^{13}$CO/C$^{18}$O ($J$ = 1-0) survey in a portion of the third Galactic quadrant (TGQ): $l$ = [219.75, 229.75]$^\circ$ and $b$ = [-5.25, 5.25]$^\circ$. The high-resolution and high-sensitivity data sets help to unravel the distributions and physical properties of the molecular clouds (MCs) in the mapped area. In the LSR velocity range from -1 to 85 km/s, the molecular material successfully traces the Local, Perseus, and Outer arms. In the TGQ, the Outer arm appears to be more prominent than that in the second Galactic quadrant (SGQ), but the Perseus arm is not as conspicuous as that in the SGQ. A total of 1,502 $^{12}$CO, 570 $^{13}$CO, and 53 C$^{18}$O molecular structures are identified, spanning over $\sim2$ and $\sim6$ orders of magnitude in size and mass, respectively. Tight mass-radius correlations and virial parameter-mass anticorrelations are observable. Yet, it seems that no clear correlations between velocity dispersion and effective radius can be found over the full dynamic range. The vertical distribution of the MCs renders evident pictures of the Galactic warp and flare.Comment: 22 pages, 13 figures, 7 tables (with machine-readable versions), published in ApJ

Retrospective analysis of 217 fatal intoxication autopsy cases from 2009 to 2021: temporal trends in fatal intoxication at Tongji center for medicolegal expertise, Hubei, China

This retrospective analysis of fatal intoxication case autopsies was performed at Tongji Center for Medicolegal Expertise in Hubei (TCMEH) from 2009 to 2021 to obtain up-to-date information on intoxication cases. The objective was to describe important data about evolving patterns in intoxication occurrences, enhance public safety policies, and assist forensic examiners and police in more efficient handling of such cases. Analyses based on sex, age, topical exposure routes, toxic agents, and mode of death were performed using 217 records of intoxication cases collected from TCMEH as a sample, and the results were compared with reports previously published (from 1999 to 2008) from this institution. Deaths from intoxications occurred at a higher rate in males than in females and were most common among individuals aged 30–39 years. The most frequent method of exposure was oral ingestion. The causative agents of deadly intoxications have changed when compared to the data from the previous 10 years. For instance, deaths from amphetamine overdoses are becoming more prevalent gradually, whereas deaths due to carbon monoxide and rodenticide intoxication have declined dramatically. In 72 cases, pesticides continued to be the most frequent intoxication cause. A total of 60.4% of the deaths were accidental exposure. Men died from accidents at a higher rate than women, although women were more likely to commit suicide. Particular focus is needed on the use of succinylcholine, cyanide, and paraquat in homicides

Anisotropic high cycle fatigue property of Sc and Zr-modified Al-Mg alloy fabricated by laser powder bed fusion

This work investigates the defects (pore and lack of fusion), microstructure, and fatigue properties of Sc and Zr-modified Al–Mg alloy on different building directions fabricated by laser powder bed fusion (LPBF). The results showed that transversely deposited (TD) samples exhibited a superior fatigue strength (100.5 MPa) compared to that (57 MPa) of the parallelly deposited (PD) sample, while their tensile and hardness properties were similar. This phenomenon is attributed to two factors: defects and grain/microstructure. For the defects, the lack of fusion resulted in a higher stress concentration in the PD samples than that of the TD samples in the crack initiation stage. For the microstructure, owing to the indistinctive crack deflection and possible cyclic softening of the columnar grains, a decrement in fatigue resistance appears. Thus, the different crack propagation paths led to different columnar grain/equiaxed grain area ratios for the anisotropic fatigue properties. Furthermore, in the TD samples, some grains, with the || building direction orientation, partly led to a higher fatigue resistance of the TD sample than of the PD sample owing to the exceptional dislocation formation