Hand Pose Estimation with Mems-Ultrasonic Sensors

Hand tracking is an important aspect of human-computer interaction and has a wide range of applications in extended reality devices. However, current hand motion capture methods suffer from various limitations. For instance, visual-based hand pose estimation is susceptible to self-occlusion and changes in lighting conditions, while IMU-based tracking gloves experience significant drift and are not resistant to external magnetic field interference. To address these issues, we propose a novel and low-cost hand-tracking glove that utilizes several MEMS-ultrasonic sensors attached to the fingers, to measure the distance matrix among the sensors. Our lightweight deep network then reconstructs the hand pose from the distance matrix. Our experimental results demonstrate that this approach is both accurate, size-agnostic, and robust to external interference. We also show the design logic for the sensor selection, sensor configurations, circuit diagram, as well as model architecture

A Study on Design Process Integration between Marketing and R&D of Notebook

This study focuses on building a framework which calculates the weights of FAHP (Fuzzy Analytical Hierarchical Process) method , then integrates the analysis tools such as FQFD (Fuzzy Quality Function Development) and FFMEA (Fuzzy Failure Mode and Effects Analysis) into the framework to construct a two-phase product specifications evaluation process. Therefore, this study builds a framework and process of the new product specification evaluation which integrates the marketing attributes (the evaluation of the customers’ demands)、research attributes and development attributes and manufacture attributes (the evaluation of the failures and defects of the product specifications). It allows the product specifications which are produced by braining storm to be proceeded the evaluation before the prototype test phase and find the optimum product specification. It also can further the companies to optimize the organization resources. This research focuses on not only determining, but also transferring the market attributes to the product R&D specification in order to realize the relationship between the consumers’ demands and the product specification. According to the methodologies represented, this study attempts to fill the gap in the literature by providing an integrative research framework and offers this framework to contribute the tasks and operations in the initial phase of the new product development and build the framework of multidimensional product specifications evaluation. Finally, an example of Notebook is used to illustrate the proposed approach

Identification of chemical inducers of metastasis-related cell differentiation events using peptide microarrays

The epithelial-mesenchymal transition (EMT) is a key indicator of cancer progression and metastasis in vivo. The most important inducer of EMT is activation of the transforming growth factor beta (TGF-β) pathway. In addition to initiating EMT, TGF-β is able to cause cancer cells to switch cell states from the non-stem cancer cell (NSCC) to the more invasive and tumorigenic cancer stem cell (CSC) state. Investigation into factors that can activate the TGF-β pathway, and thereby initiate EMT or the NSCC-to-CSC conversion, is therefore of critical importance. It is well known that the chemical environment immediately surrounding the cell determines cell differentiation events. Small molecules such as peptides, then, can induce such events in cells that are bound to the peptides. In this project, we aimed to identify peptide ligands that were able to induce EMT in cells adhered to the peptide surface. Five peptides previously discovered through phage display (panning against MDA-MB-231 cells) along with three control peptides, were printed onto gold-coated glass slides in a patterned array using a DNA microarray printer and tested against NMuMG cells. The arrays of cells were then fixed and stained for eCadherin (an epithelial marker). We found that after four days of culture on the peptide-modified surfaces, eCadherin levels were decreased on two of the five test peptide surfaces, as well as in both of the positive control peptide surfaces, suggesting that those cell populations underwent EMT. Future studies will indicate whether these peptides can additionally induce the NSCC-to-CSC conversion. *Indicates faculty mentor

A Supramolecular Strategy to Assemble Multifunctional Viral Nanoparticles

Using a one-pot approach driven by the supramolecular interaction between β-cyclodextrin and adamantyl moieties, multifunctional viral nanoparticles can be facilely formulated for biomedical applications