1,846 research outputs found
An Intelligent Auxiliary Vacuum Brake System
The purpose of this paper focuses on designing an intelligent, compact, reliable, and robust auxiliary vacuum brake system (VBS) with Kalman filter and self-diagnosis scheme. All of the circuit elements in the designed system are integrated into one programmable system-on-chip (PSoC) with entire computational algorithms implemented by software. In this system, three main goals are achieved: (a) Kalman filter and hysteresis controller algorithms are employed within PSoC chip by software to surpass the noises and disturbances from hostile surrounding in a vehicle. (b) Self-diagnosis scheme is employed to identify any breakdown element of the auxiliary vacuum brake system. (c) Power MOSFET is utilized to implement PWM pump control and compared with relay control. More accurate vacuum pressure control has been accomplished as well as power energy saving. In the end, a prototype has been built and tested to confirm all of the performances claimed above
Drosophila Decapping Protein 1, dDcp1, Is a Component of the oskar mRNP Complex and Directs Its Posterior Localization in the Oocyte
SummaryIn Drosophila, posterior deposition of oskar (osk) mRNA in oocytes is critical for both pole cell and abdomen formation. Exon junction complex components, translational regulation factors, and other proteins form an RNP complex that is essential for directing osk mRNA to the posterior of the oocyte. Until now, it has not been clear whether the mRNA degradation machinery is involved in regulating osk mRNA deposition. Here we show that Drosophila decapping protein 1, dDcp1, is a posterior group gene required for the transport of osk mRNA. In oocytes, dDcp1 is localized posteriorly in an osk mRNA position- and dosage-dependent manner. In nurse cells, dDcp1 colocalizes with dDcp2 and Me31B in discrete foci that may be related to processing bodies (P bodies), which are sites of active mRNA degradation. Thus, as well as being a general factor required for mRNA decay, dDcp1 is an essential component of the osk mRNP localization complex
EFFECT OF BACKPACK ON SELECTED GAIT PARAMETERS OF PRIMARY SCHOOL CHilDREN
The purpose of this study was to compare the effects of a backpack load of 15% body weight (BW) on selected gait parameters of primary school children. Ten participants were recruited from primary school (age: 10.3 ± 0.48 yrs; hI: 141.3 ± 0 .41 cm; mass:
38.1 ± 6.1 kg). A JVC 9800 (60 hz) video camera synchronized with an AMTI force plate (1200 Hz) were used to collect data. A repeated measure t-test (p < 0.05) was used for group comparisons. The backpack load did not affect either the proportionate time of the stance phase, swing phase, or the magnitude of selected vertical and anterioposterior ground reaction force parameters. However, the 15% backpack load did cause a significant increase in proportionate double leg support time
A shallow physics-informed neural network for solving partial differential equations on surfaces
In this paper, we introduce a shallow (one-hidden-layer) physics-informed
neural network for solving partial differential equations on static and
evolving surfaces. For the static surface case, with the aid of level set
function, the surface normal and mean curvature used in the surface
differential expressions can be computed easily. So instead of imposing the
normal extension constraints used in literature, we write the surface
differential operators in the form of traditional Cartesian differential
operators and use them in the loss function directly. We perform a series of
performance study for the present methodology by solving Laplace-Beltrami
equation and surface diffusion equation on complex static surfaces. With just a
moderate number of neurons used in the hidden layer, we are able to attain
satisfactory prediction results. Then we extend the present methodology to
solve the advection-diffusion equation on an evolving surface with given
velocity. To track the surface, we additionally introduce a prescribed hidden
layer to enforce the topological structure of the surface and use the network
to learn the homeomorphism between the surface and the prescribed topology. The
proposed network structure is designed to track the surface and solve the
equation simultaneously. Again, the numerical results show comparable accuracy
as the static cases. As an application, we simulate the surfactant transport on
the droplet surface under shear flow and obtain some physically plausible
results
Examination of the Relationship between In-Store Environmental Factors and Fruit and Vegetable Purchasing among Hispanics.
Retail food environments have received attention for their influence on dietary behaviors and for their nutrition intervention potential. To improve diet-related behaviors, such as fruit and vegetable (FV) purchasing, it is important to examine its relationship with in-store environmental characteristics. This study used baseline data from the "El Valor de Nuestra Salud" study to examine how in-store environmental characteristics, such as product availability, placement and promotion, were associated with FV purchasing among Hispanic customers in San Diego County. Mixed linear regression models indicated that greater availability of fresh FVs was associated with a 0.02 increase and 3.69 fewer dollars on FVs compared to women, controlling for covariates (p = 0.02). These results can help inform interventions targeting in-store environmental characteristics to encourage FV purchasing among Hispanics
Current and state of the art on the electrophysiologic characteristics and catheter ablation of arrhythmogenic right ventricular dysplasia/cardiomyopathy
AbstractArrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an inherited genetic disease caused by defective desmosomal proteins, and it has typical histopathological features characterized by predominantly progressive fibro-fatty infiltration of the right ventricle. Clinical presentations of ARVD/C vary from syncope, progressive heart failure (HF), ventricular tachyarrhythmias, and sudden cardiac death (SCD). The 2010 modified Task Force criteria were established to facilitate the recognition and diagnosis of ARVD/C. An implantable cardiac defibrillator (ICD) remains to be the cornerstone in prevention of SCD in patients fulfilling the diagnosis of definite ARVD/C, especially among ARVD/C patients with syncope, hemodynamically unstable ventricular tachycardia (VT), ventricular fibrillation, and aborted SCD. Further risk stratification is clinically valuable in the management of patients with borderline or possible ARVD/C and mutation carriers of family members. However, given the entity of heterogeneous penetrance and non-uniform phenotypes, the standardization of clinical practice guidelines for at-risk individuals will be the next frontier to breakthrough.Antiarrhythmic drugs are prescribed frequently to patients experiencing frequent ventricular tachyarrhythmias and/or appropriate ICD shocks. Amiodarone is the recommended drug of choice. Radiofrequency catheter ablation (RFCA) has been demonstrated to effectively eliminate the drug-refractory VT in patients with ARVD/C. However, the efficacy and clinical prognosis of RFCA via endocardial approach alone was disappointing prior to the era of epicardial approach. In recent years, it has been proven that the integration of endocardial and epicardial ablation by targeting the critical isthmus or eliminating abnormal electrograms within the diseased substrates could yield higher acute success and lower recurrence of ventricular tachyarrhythmias during long-term follow-up. Heart transplantation is the final option for patients with extensive disease, biventricular HF with uncontrollable hemodynamic compromise, and refractory ventricular tachyarrhythmias despite aggressive medical and ablation therapies
Fitting Age-Period-Cohort Models Using the Intrinsic Estimator: Assumptions and Misapplications
We thank Demography’s editorial office for the opportunity to respond to te Grotenhuis et al.’s commentary regarding the methods used and the results presented in our earlier paper (Masters et al. 2014). In this response, we briefly reply to three general themes raised in the commentary: (1) the presentation and discussion of APC results, (2) the fitting of full APC models to data for which a simpler model holds, and (3) the variation in the estimated age, period, and cohort coefficients produced by the intrinsic estimator (IE) (i.e., the “non-uniqueness property” of the IE, as referred to by Pelzer et al. (2015))
R-process beta-decay neutrino flux from binary neutron star merger and collapsar
This study investigates the antineutrinos production by -decay of
-process nuclei in two astrophysical sites that are capable of producing
gamma-ray bursts (GRBs): binary neutron star mergers (BNSMs) and collapsars,
which are promising sites for heavy element nucleosynthesis. We employ a
simplified method to compute the -decay energy spectrum and
consider two representative thermodynamic trajectories for -process
simulations, each with four sets of distribution. The time evolution of
the spectrum is derived for both the dynamical ejecta and the disk
wind for BNSMs and collapsar outflow, based on approximated mass outflow rates.
Our results show that the has an average energy of approximately 3
to 9~MeV, with a high energy tail of up to 20 MeV. The flux
evolution is primarily determined by the outflow duration, and can thus remain
large for ~s and ~s for BNSMs and
collapsars, respectively. For a single merger or collapsar at 40~Mpc, the
flux is ~cm~s, indicating a
possible detection horizon up to ~Mpc for Hyper-kamiokande. We also
estimate their contributions to the diffuse background. Our results
suggest that although the flux from BNSMs is roughly 4--5 orders of magnitude
lower than that from the regular core-collapse supernovae, those from
collapsars can possibly contribute a non-negligible fraction to the total
diffuse flux at energy ~MeV, with a large uncertainty
depending on the unknown rate of collapsars capable of hosting the -process.Comment: 13 pages, 7 figure
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