Tracking intracavernously injected adipose-derived stem cells to bone marrow.

The intracavernous (i.c.) injection of stem cells (SCs) has been shown to improve erectile function in various erectile dysfunction (ED) animal models. However, the tissue distribution of the injected cells remains unknown. In this study we tracked i.c.-injected adipose-derived stem cells (ADSCs) in various tissues. Rat paratesticular fat was processed for ADSC isolation and culture. The animals were then subject to cavernous nerve (CN) crush injury or sham operation, followed by i.c. injection of 1 million autologous or allogeneic ADSCs that were labeled with 5-ethynyl-2-deoxyuridine (EdU). Another group of rats received i.c. injection of EdU-labeled allogeneic penile smooth muscle cells (PSMCs). At 2 and 7 days post injection, penises and femoral bone marrow were processed for histological analyses. Whole femoral bone marrows were also analyzed for EdU-positive cells by flow cytometry. The results show that ADSCs exited the penis within days of i.c. injection and migrated preferentially to bone marrow. Allogenicity did not affect the bone marrow appearance of ADSCs at either 2 or 7 days, whereas CN injury reduced the number of ADSCs in bone marrow significantly at 7 but not 2 days. The significance of these results in relation to SC therapy for ED is discussed

Mass Spectrum and Bounds on the Couplings in Yukawa Models With Mirror-Fermions

The $\rm SU(2)_L\otimes SU(2)_R$ symmetric Yukawa model with mirror-fermions in the limit where the mirror-fermion is decoupled is studied both analytically and numerically. The bare scalar self-coupling $\lambda$ is fixed at zero and infinity. The phase structure is explored and the relevant phase transition is found to be consistent with a second order one. The fermionic mass spectrum close to that transition is discussed and a first non-perturbative estimate of the influence of fermions on the upper and lower bounds on the renormalized scalar self-coupling is given. Numerical results are confronted with perturbative predictions.Comment: 7 (Latex) page

Cusp Summations and Cusp Relations of Simple Quad Lenses

We review five often used quad lens models, each of which has analytical solutions and can produce four images at most. Each lens model has two parameters, including one that describes the intensity of non-dimensional mass density, and the other one that describes the deviation from the circular lens. In our recent work, we have found that the cusp and the fold summations are not equal to 0, when a point source infinitely approaches a cusp or a fold from inner side of the caustic. Based on the magnification invariant theory, which states that the sum of signed magnifications of the total images of a given source is a constant, we calculate the cusp summations for the five lens models. We find that the cusp summations are always larger than 0 for source on the major cusps, while can be larger or smaller than 0 for source on the minor cusps. We also find that if these lenses tend to the circular lens, the major and minor cusp summations will have infinite values, and with positive and negative signs respectively. The cusp summations do not change significantly if the sources are slightly deviated from the cusps. In addition, through the magnification invariants, we also derive the analytical signed cusp relations on the axes for three lens models. We find that both on the major and the minor axes the larger the lenses deviated from the circular lens, the larger the signed cusp relations. The major cusp relations are usually larger than the absolute minor cusp relations, but for some lens models with very large deviation from circular lens, the minor cusp relations can be larger than the major cusp relations.Comment: 8 pages, 4 figures, accepted for publication in MNRA

Permutation Symmetric Critical Phases in Disordered Non-Abelian Anyonic Chains

Topological phases supporting non-abelian anyonic excitations have been proposed as candidates for topological quantum computation. In this paper, we study disordered non-abelian anyonic chains based on the quantum groups $SU(2)_k$, a hierarchy that includes the $\nu=5/2$ FQH state and the proposed $\nu=12/5$ Fibonacci state, among others. We find that for odd $k$ these anyonic chains realize infinite randomness critical {\it phases} in the same universality class as the $S_k$ permutation symmetric multi-critical points of Damle and Huse (Phys. Rev. Lett. 89, 277203 (2002)). Indeed, we show that the pertinent subspace of these anyonic chains actually sits inside the ${\mathbb Z}_k \subset S_k$ symmetric sector of the Damle-Huse model, and this ${\mathbb Z}_k$ symmetry stabilizes the phase.Comment: 13 page

Multipole Gravitational Lensing and High-order Perturbations on the Quadrupole Lens

An arbitrary surface mass density of gravitational lens can be decomposed into multipole components. We simulate the ray-tracing for the multipolar mass distribution of generalized SIS (Singular Isothermal Sphere) model, based on the deflection angles which are analytically calculated. The magnification patterns in the source plane are then derived from inverse shooting technique. As have been found, the caustics of odd mode lenses are composed of two overlapping layers for some lens models. When a point source traverses such kind of overlapping caustics, the image numbers change by \pm 4, rather than \pm 2. There are two kinds of images for the caustics. One is the critical curve and the other is the transition locus. It is found that the image number of the fold is exactly the average value of image numbers on two sides of the fold, while the image number of the cusp is equal to the smaller one. We also focus on the magnification patterns of the quadrupole (m = 2) lenses under the perturbations of m = 3, 4 and 5 mode components, and found that one, two, and three butterfly or swallowtail singularities can be produced respectively. With the increasing intensity of the high-order perturbations, the singularities grow up to bring sixfold image regions. If these perturbations are large enough to let two or three of the butterflies or swallowtails contact, eightfold or tenfold image regions can be produced as well. The possible astronomical applications are discussed.Comment: 24 pages, 6 figure

Thermalization and temperature distribution in a driven ion chain

We study thermalization and non-equilibrium dynamics in a dissipative quantum many-body system -- a chain of ions with two points of the chain driven by thermal bath under different temperature. Instead of a simple linear temperature gradient as one expects from the classical heat diffusion process, the temperature distribution in the ion chain shows surprisingly rich patterns, which depend on the ion coupling rate to the bath, the location of the driven ions, and the dissipation rates of the other ions in the chain. Through simulation of the temperature evolution, we show that these unusual temperature distribution patterns in the ion chain can be quantitatively tested in experiments within a realistic time scale.Comment: 5 pages, 5 figure