413 research outputs found

    Cross-Layer Optimization of Fast Video Delivery in Cache-Enabled Relaying Networks

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    This paper investigates the cross-layer optimization of fast video delivery and caching for minimization of the overall video delivery time in a two-hop relaying network. The half-duplex relay nodes are equipped with both a cache and a buffer which facilitate joint scheduling of fetching and delivery to exploit the channel diversity for improving the overall delivery performance. The fast delivery control is formulated as a two-stage functional non-convex optimization problem. By exploiting the underlying convex and quasi-convex structures, the problem can be solved exactly and efficiently by the developed algorithm. Simulation results show that significant caching and buffering gains can be achieved with the proposed framework, which translates into a reduction of the overall video delivery time. Besides, a trade-off between caching and buffering gains is unveiled.Comment: 7 pages, 4 figures; accepted for presentation at IEEE Globecom, San Diego, CA, Dec. 201

    Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation

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    BACKGROUND: We have recently reported the expression of murine Implantation Serine Proteinase genes in pre-implantation embryos (ISP1) and uterus (ISP1 and ISP2). These proteinases belong to the S1 proteinase family and are similar to mast cell tryptases, which function as multimers. RESULTS: Here, we report the purification and initial characterization of ISP1 and 2 with respect to their physico-chemical properties and physiological function. In addition to being co-expressed in uterus, we show that ISP1 and ISP2 are also co-expressed in the pre-implantation embryo. Together, they form a heterodimer with an approximate molecular weight of 63 kD. This complex is the active form of the enzyme, which we have further characterized as being trypsin-like, based on substrate and inhibitor specificities. In addition to having a role in embryo hatching and outgrowth, we demonstrate that ISP enzyme is localized to the site of embryo invasion during implantation and that its activity is important for successful implantation in vivo. CONCLUSION: On the basis of similarities in structural, chemical, and functional properties, we suggest that this ISP enzyme complex represents the classical hatching enzyme, strypsin. Our results demonstrate a critical role for ISP in embryo hatching and implantation

    Cache-Aided Non-Orthogonal Multiple Access: The Two-User Case

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    In this paper, we propose a cache-aided non-orthogonal multiple access (NOMA) scheme for spectrally efficient downlink transmission. The proposed scheme not only reaps the benefits associated with NOMA and caching, but also exploits the data cached at the users for interference cancellation. As a consequence, caching can help to reduce the residual interference power, making multiple decoding orders at the users feasible. The resulting flexibility in decoding can be exploited for improved NOMA detection. We characterize the achievable rate region of cache-aided NOMA and derive the Pareto optimal rate tuples forming the boundary of the rate region. Moreover, we optimize cache-aided NOMA for minimization of the time required for completing file delivery. The optimal decoding order and the optimal transmit power and rate allocation are derived as functions of the cache status, the file sizes, and the channel conditions. Simulation results confirm that, compared to several baseline schemes, the proposed cache-aided NOMA scheme significantly expands the achievable rate region and increases the sum rate for downlink transmission, which translates into substantially reduced file delivery times.Comment: Accepted for publication in IEEE J. Sel. Topics Signal Process. arXiv admin note: text overlap with arXiv:1712.0955

    Asymptotic Gluon Shadowing

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    We examine the low Bjorken xx gluon distribution in nuclei in the asymptotic region.Comment: 7 pages, 1 figur
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