413 research outputs found
Cross-Layer Optimization of Fast Video Delivery in Cache-Enabled Relaying Networks
This paper investigates the cross-layer optimization of fast video delivery
and caching for minimization of the overall video delivery time in a two-hop
relaying network. The half-duplex relay nodes are equipped with both a cache
and a buffer which facilitate joint scheduling of fetching and delivery to
exploit the channel diversity for improving the overall delivery performance.
The fast delivery control is formulated as a two-stage functional non-convex
optimization problem. By exploiting the underlying convex and quasi-convex
structures, the problem can be solved exactly and efficiently by the developed
algorithm. Simulation results show that significant caching and buffering gains
can be achieved with the proposed framework, which translates into a reduction
of the overall video delivery time. Besides, a trade-off between caching and
buffering gains is unveiled.Comment: 7 pages, 4 figures; accepted for presentation at IEEE Globecom, San
Diego, CA, Dec. 201
Social Media and the perfect crime: Towards the death of reality, representation and the murder of resistance.
Master'sMASTER OF ART
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Metastatic Renal Cell Carcinoma to the Sinonasal Cavity: A Case Series
Objectives: To describe the presentation, work-up, and management of patients with metastatic renal cell carcinoma (RCC) to the sinonasal cavity and skull base, and to describe our current treatment algorithm of endoscopic surgical resection followed by radiation therapy. Design: Retrospective review of two recent cases from our institution over a 1-year period, with a relevant review of the literature. Setting: A large regional tertiary care facility. Participants: Consecutive cases of RCC with metastases to the sinonasal cavity presenting to our institution. Main Outcome Measures: Preoperative and postoperative sinonasal outcome test (SNOT)-22 scores, duration of hospital stay, complications, and local disease control Results: Patients in this series underwent preoperative embolization followed by endoscopic resection without complication. Postoperatively they were treated with radiation therapy. They experienced improvement in their SNOT-22 scores and are currently free of local disease. Conclusion: Metastatic RCC to the sinonasal cavity can be safely treated with preoperative embolization followed by endoscopic surgical resection and radiation therapy, which can result in improvement in sinonasal quality of life and is a potential adjunct for local control of disease
Implantation Serine Proteinases heterodimerize and are critical in hatching and implantation
BACKGROUND: We have recently reported the expression of murine Implantation Serine Proteinase genes in pre-implantation embryos (ISP1) and uterus (ISP1 and ISP2). These proteinases belong to the S1 proteinase family and are similar to mast cell tryptases, which function as multimers. RESULTS: Here, we report the purification and initial characterization of ISP1 and 2 with respect to their physico-chemical properties and physiological function. In addition to being co-expressed in uterus, we show that ISP1 and ISP2 are also co-expressed in the pre-implantation embryo. Together, they form a heterodimer with an approximate molecular weight of 63 kD. This complex is the active form of the enzyme, which we have further characterized as being trypsin-like, based on substrate and inhibitor specificities. In addition to having a role in embryo hatching and outgrowth, we demonstrate that ISP enzyme is localized to the site of embryo invasion during implantation and that its activity is important for successful implantation in vivo. CONCLUSION: On the basis of similarities in structural, chemical, and functional properties, we suggest that this ISP enzyme complex represents the classical hatching enzyme, strypsin. Our results demonstrate a critical role for ISP in embryo hatching and implantation
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Outcomes and prognostic factors in parotid gland malignancies: A 10-year single center experience.
Objectives:To describe a 10-year single center experience with parotid gland malignancies and to determine factors affecting outcomes. Study Design:Retrospective review. Methods:The institutional cancer registry was used to identify patients treated surgically for malignancies of the parotid gland between January 2005 and December 2014. Clinical and pathologic data were collected retrospectively from patient charts and analyzed for their association with overall survival (OS) and disease-free survival (DFS). Results:Two hundred patients were identified. Mean age at surgery was 57.8 years, and mean follow-up time was 52 months. One hundred two patients underwent total parotidectomy, while 77 underwent superficial parotidectomy, and 21 underwent deep lobe resection. Seventy patients (35%) required facial nerve (FN) sacrifice. Acinic cell carcinoma was the most common histologic type (22%), followed by mucoepidermoid carcinoma (21.5%) and adenoid cystic carcinoma (12.5%). Twenty-nine patients (14.5%) experienced recurrences, with mean time to recurrence of 23.6 months (range: 1-82 months). Five- and 10-year OS were 81% and 73%, respectively. Five- and 10-year DFS were 80% and 73%, respectively. In univariate analyses, age > 60, histologic type, positive margins, high grade, T-stage, node positivity, perineural invasion, and FN involvement were predictors of OS and DFS. In the multivariate analysis, histology, positive margins, node positivity, and FN involvement were independent predictors of OS and DFS. Conclusions:Our single-center experience of 200 patients suggests that histology, positive margins, node positivity, and FN involvement are independently associated with outcomes in parotid malignancies. Level of Evidence:4
Cache-Aided Non-Orthogonal Multiple Access: The Two-User Case
In this paper, we propose a cache-aided non-orthogonal multiple access (NOMA)
scheme for spectrally efficient downlink transmission. The proposed scheme not
only reaps the benefits associated with NOMA and caching, but also exploits the
data cached at the users for interference cancellation. As a consequence,
caching can help to reduce the residual interference power, making multiple
decoding orders at the users feasible. The resulting flexibility in decoding
can be exploited for improved NOMA detection. We characterize the achievable
rate region of cache-aided NOMA and derive the Pareto optimal rate tuples
forming the boundary of the rate region. Moreover, we optimize cache-aided NOMA
for minimization of the time required for completing file delivery. The optimal
decoding order and the optimal transmit power and rate allocation are derived
as functions of the cache status, the file sizes, and the channel conditions.
Simulation results confirm that, compared to several baseline schemes, the
proposed cache-aided NOMA scheme significantly expands the achievable rate
region and increases the sum rate for downlink transmission, which translates
into substantially reduced file delivery times.Comment: Accepted for publication in IEEE J. Sel. Topics Signal Process. arXiv
admin note: text overlap with arXiv:1712.0955
Asymptotic Gluon Shadowing
We examine the low Bjorken gluon distribution in nuclei in the asymptotic
region.Comment: 7 pages, 1 figur
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