Joint-Modal Label Denoising for Weakly-Supervised Audio-Visual Video Parsing

This paper focuses on the weakly-supervised audio-visual video parsing task, which aims to recognize all events belonging to each modality and localize their temporal boundaries. This task is challenging because only overall labels indicating the video events are provided for training. However, an event might be labeled but not appear in one of the modalities, which results in a modality-specific noisy label problem. In this work, we propose a training strategy to identify and remove modality-specific noisy labels dynamically. It is motivated by two key observations: 1) networks tend to learn clean samples first; and 2) a labeled event would appear in at least one modality. Specifically, we sort the losses of all instances within a mini-batch individually in each modality, and then select noisy samples according to the relationships between intra-modal and inter-modal losses. Besides, we also propose a simple but valid noise ratio estimation method by calculating the proportion of instances whose confidence is below a preset threshold. Our method makes large improvements over the previous state of the arts (e.g. from 60.0\% to 63.8\% in segment-level visual metric), which demonstrates the effectiveness of our approach. Code and trained models are publicly available at \url{https://github.com/MCG-NJU/JoMoLD}.Comment: Accepted by ECCV 202

One-Fe versus Two-Fe Brillouin Zone of Fe-Based Superconductors: Creation of the Electron Pockets via Translational Symmetry Breaking

We investigate the physical effects of translational symmetry breaking in Fe-based high-temperature superconductors due to alternating anion positions. In the representative parent compounds, including the newly discovered Fe-vacancy-ordered $\mathrm{K_{0.8}Fe_{1.6}Se_2}$, an unusual change of orbital character is found across the one-Fe Brillouin zone upon unfolding the first-principles band structure and Fermi surfaces, suggesting that covering a larger one-Fe Brillouin zone is necessary in experiments. Most significantly, the electron pockets (critical to the magnetism and superconductivity) are found only created with the broken symmetry, advocating strongly its full inclusion in future studies, particularly on the debated nodal structures of the superconducting order parameter.Comment: Accepted by Physical Review Letters. Updated in Figure 2 and supplementary informatio

Existence of positive solutions for singular p-Laplacian Hadamard fractional differential equations with the derivative term contained in the nonlinear term

In this paper, based on the properties of Green function and the eigenvalue of a corresponding linear operator, the existence of positive solutions is investigated by spectral analysis for a infinite-points singular p-Laplacian Hadamard fractional differential equation boundary value problem, and an example is given to demonstrate the validity of our main results

Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets

The connection between inflammation and tumourigenesis has been well established. However, the detailed molecular mechanism underlying inflammation-associated tumourigenesis remains unknown because this process involves a complex interplay between immune microenvironments and epithelial cells. To obtain a more systematic understanding of inflammation-associated tumourigenesis as well as to identify novel therapeutic approaches, we constructed a knowledge-based network describing the development of colitis-associated colon cancer (CAC) by integrating the extracellular microenvironment and intracellular signalling pathways. Dynamic simulations of the CAC network revealed a core network module, including P53, MDM2, and AKT, that may govern the malignant transformation of colon epithelial cells in a pro-tumor inflammatory microenvironment. Furthermore, in silico mutation studies and experimental validations led to a novel finding that concurrently targeting ceramide and PI3K/AKT pathway by chemical probes or marketed drugs achieves synergistic anti-cancer effects. Overall, our network model can guide further mechanistic studies on CAC and provide new insights into the design of combinatorial cancer therapies in a rational manner

On-chip three-dimensional high-Q microcavities fabricated by femtosecond laser direct writing

We report on the fabrication of three-dimensional (3D) high-Q whispering gallery microcavities on a fused silica chip by femtosecond laser microfabriction, enabled by the 3D nature of femtosecond laser direct writing. The processing mainly consists of formation of freestanding microdisks by femtosecond laser direct writing and subsequent wet chemical etching. CO2 laser annealing is followed to smooth the microcavity surface. Microcavities with arbitrary tilting angle, lateral and vertical positioning are demonstrated, and the quality (Q)-factor of a typical microcavity is measured to be up to 1.07x10^6, which is currently limited by the low spatial resolution of motion stage used during the laser patterning and can be improved with motion stages of higher resolutions.Comment: 17 pages, 3 figure