42 research outputs found

    Multidisciplinary Staffing in a Graduate Writing Center: Making Writing Labor Visible, Valued, and Shared

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    Writing studies and writing center scholars have recently focused much-needed attention on how graduate student writers are taught, mentored, and supported. This scholarship also points to a persistent and stubborn conundrum: Graduate students must write their way into disciplinary belonging, yet most advisors lack a language for, or even awareness of, the specialized practices and tacit expectations shaping written discourse in their fields. While graduate student–serving writing centers help fill this writing-support gap, a reliance on English and humanities graduate students for staff reproduces a status quo in which the genre awareness and rhetorical vocabulary needed to mentor advanced academic writers are neither widely distributed nor recognized and valued. This essay offers the counterexample of a graduate writing center whose consultants hail primarily from master’s and doctoral programs in the sciences and social sciences. Using feminist social reproduction theory to examine this case study of one graduate writing center, the authors explore how multidisciplinary staffing resists the enclaving of writing process and rhetorical knowledge and points to a future in which the responsibility for mentoring graduate student writers is visible, valued, and shared

    High levels of anti-tuberculin (IgG) antibodies correlate with the blocking of T-cell proliferation in individuals with high exposure to Mycobacterium tuberculosis

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    SummaryObjectivesTo determine the effect of anti-tuberculin antibodies in the T-cell proliferation in response to tuberculin and Candida antigens in individuals with different levels of tuberculosis (TB) risk.MethodsSixteen high-risk TB individuals, 30 with an intermediate TB risk (group A), and 45 with a low TB risk (group B), as well as 49 control individuals, were studied. Tuberculin skin test (TST) results were analyzed and serum levels of antibodies (IgG and IgM) against purified protein derivative (PPD) were measured by ELISA. Tuberculin and Candida antigens were used to stimulate T-cell proliferation in the presence of human AB serum or autologous serum.ResultsHigh levels of anti-tuberculin IgG antibodies were found to be significantly associated with the blocking of T-cell proliferation responses in cultures stimulated with tuberculin but not with Candida antigens in the presence of autologous serum. This phenomenon was particularly frequent in high-risk individuals with high levels of anti-tuberculin IgG antibodies in the autologous serum when compared to the other risk groups, which exhibited lower levels of anti-tuberculin antibodies.ConclusionsAlthough cellular immunity plays a central role in the protection against TB, humoral immunity is critical in the control of Mycobacterium tuberculosis infection in high-risk individuals with latent TB infection

    Evidence for a Fourteenth mtDNA-Encoded Protein in the Female-Transmitted mtDNA of Marine Mussels (Bivalvia: Mytilidae)

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    BACKGROUND: A novel feature for animal mitochondrial genomes has been recently established: i.e., the presence of additional, lineage-specific, mtDNA-encoded proteins with functional significance. This feature has been observed in freshwater mussels with doubly uniparental inheritance of mtDNA (DUI). The latter unique system of mtDNA transmission, which also exists in some marine mussels and marine clams, is characterized by one mt genome inherited from the female parent (F mtDNA) and one mt genome inherited from the male parent (M mtDNA). In freshwater mussels, the novel mtDNA-encoded proteins have been shown to be mt genome-specific (i.e., one novel protein for F genomes and one novel protein for M genomes). It has been hypothesized that these novel, F- and M-specific, mtDNA-encoded proteins (and/or other F- and/or M-specific mtDNA sequences) could be responsible for the different modes of mtDNA transmission in bivalves but this remains to be demonstrated. METHODOLOGY/PRINCIPAL FINDINGS: We investigated all complete (or nearly complete) female- and male-transmitted marine mussel mtDNAs previously sequenced for the presence of ORFs that could have functional importance in these bivalves. Our results confirm the presence of a novel F genome-specific mt ORF, of significant length (>100aa) and located in the control region, that most likely has functional significance in marine mussels. The identification of this ORF in five Mytilus species suggests that it has been maintained in the mytilid lineage (subfamily Mytilinae) for ∼13 million years. Furthermore, this ORF likely has a homologue in the F mt genome of Musculista senhousia, a DUI-containing mytilid species in the subfamily Crenellinae. We present evidence supporting the functionality of this F-specific ORF at the transcriptional, amino acid and nucleotide levels. CONCLUSIONS/SIGNIFICANCE: Our results offer support for the hypothesis that "novel F genome-specific mitochondrial genes" are involved in key biological functions in bivalve species with DUI

    Nonlinear mean reversion in the G7 stock markets

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    We utilize the nonlinear unit root tests proposed by Park and Shintani (2005) and find strong evidence of nonlinear mean reversion between a US stock index and the stock indices in France, Germany, Italy and the UK. We identified an inaction band where deviations of these international stock indices from the US stock index follow a unit root process. Outside the band, however, they exhibit strong mean reversion properties. We show that standard linear unit root tests are not able to detect nonlinear cointegration and will yield the erroneous conclusion that the stock indices are not cointegrated.

    Expected Equity Returns and the Demand for Money

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    This paper investigates the role of equity markets in the determination of money demand. Expected equity returns are found to be significant determinants of money demand in the long run. We also uncover a strong positive drift in the elasticity of money demand with respect to expected equity returns. Moreover, this elasticity has recently become positive. We explain the puzzle of positive interest elasticity by modifying a conventional model of money demand. We show that if equities are also allowed to provide some liquidity, then the model can support both positive and negative elasticities with respect to expected returns.

    Half-life bias correction and the G7 stock markets

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    We look at alternative methods to correct a downward bias in half-life estimates of relative stock prices among the G7 countries. We compare a grid-[alpha] median-unbiased method and a recursive mean adjustment method.International equity prices Recursive mean adjustment Unit-root process

    Cognitive ability and the division of labor in urban ghettos: Evidence from gang activity in U.S. data

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    a b s t r a c t Hernstein and Murray (1994) famously argued that the division of labor in modern society is determined by individual differences in cognitive ability. This paper shows that differences in cognitive ability can also determine the division of labor in poor urban areas. We estimate the effect of IQ on time-to-first gang participation with data from the National Longitudinal Survey of Youth (NLSY97) and Project on Human Development in Chicago Neighborhoods (PHDCN). Results from both the NLSY97 and PHDCN indicate that low-IQ is a robust predictor of gang participation. There are two plausible explanations of this main finding: (1) low-IQ individuals may have comparative advantage in violence as their opportunity costs of engaging in legal activities are low and (2) gangs may prefer low-IQ individuals as a way to reduce agency costs. We find strong evidence in support of the hypothesis that persons with lower IQs have comparative advantage in criminal activity in the PHDCN dataset
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