7 research outputs found
Improving awareness of health hazards associated with air pollution in primary school children: Design and test of didactic tools
One of the objectives of the MAPEC-Life project is raising children’s
awareness on air quality and its health effects. To achieve
this goal, we designed didactic tools for primary school students,
including leaflets with more information for teachers, a cartoon,
and three educational videogames. The tools were then tested
with 266 children who attended six primary schools in four Italian
cities. A control group of 51 children received only explanations
from teachers. An improvement in knowledge after using
the audiovisual package was demonstrated, with higher efficacy
compared with the control group. In addition, the use of
videogames was greatly appreciated
Lifestyles and socio-cultural factors among children aged 6-8 years from five Italian towns: The MAPEC-LIFE study cohort
Background: Lifestyles profoundly determine the quality of an individual’s health and life since his childhood.
Many diseases in adulthood are avoidable if health-risk behaviors are identified and improved at an early stage of
life. The aim of the present research was to characterize a cohort of children aged 6–8 years selected in order to
perform an epidemiological molecular study (the MAPEC_LIFE study), investigate lifestyles of the children that
could have effect on their health status, and assess possible association between lifestyles and socio-cultural factors.
Methods: A questionnaire composed of 148 questions was administered in two different seasons to parents of
children attending 18 primary schools in five Italian cities (Torino, Brescia, Pisa, Perugia and Lecce) to obtain
information regarding the criteria for exclusion from the study, demographic, anthropometric and health
information on the children, as well as some aspects on their lifestyles and parental characteristics. The results
were analyzed in order to assess the frequency of specific conditions among the different seasons and cities and
the association between lifestyles and socio-economic factors.
Results: The final cohort was composed of 1,164 children (50.9 boys, 95.4% born in Italy). Frequency of some
factors appeared different in terms of the survey season (physical activity in the open air, the ways of cooking
certain foods) and among the various cities (parents’ level of education and rate of employment, sport, traffic
near the home, type of heating, exposure to passive smoking, ways of cooking certain foods). Exposure to
passive smoking and cooking fumes, obesity, residence in areas with heavy traffic, frequency of outdoor play and
consumption of barbecued and fried foods were higher among children living in families with low educational
and/or occupational level while children doing sports and consuming toasted bread were more frequent in families
with high socio-economic level.
Conclusions: The socio-economic level seems to affect the lifestyles of children enrolled in the study including
those that could cause health effects. Many factors are linked to the geographical area and may depend on
environmental, cultural and social aspects of the city of residence
In-house cyclotron production of high-purity Tc-99m and Tc-99m radiopharmaceuticals
In the last years, the technology for producing the important medical radionuclide technetium-99m by cyclotrons has become sufficiently mature to justify its introduction as an alternative source of the starting precursor [99mTc][TcO4]-ubiquitously employed for the production of99mTc-radiopharmaceuticals in hospitals. These technologies make use almost exclusively of the nuclear reaction100Mo(p,2n)99mTc that allows direct production of Tc-99m. In this study, it is conjectured that this alternative production route will not replace the current supply chain based on the distribution of99Mo/99mTc generators, but could become a convenient emergency source of Tc-99m only for in-house hospitals equipped with a conventional, low-energy, medical cyclotron. On this ground, an outline of the essential steps that should be implemented for setting up a hospital radiopharmacy aimed at the occasional production of Tc-99m by a small cyclotron is discussed. These include (1) target production, (2) irradiation conditions, (3) separation/purification procedures, (4) terminal sterilization, (5) quality control, and (6) Mo-100 recovery. To address these issues, a comprehensive technology for cyclotron-production of Tc-99m, developed at the Legnaro National Laboratories of the Italian National Institute of Nuclear Physics (LNL-INFN), will be used as a reference example