6,696 research outputs found
Atom interferometry in the presence of an external test mass
The influence of an external test mass on the phase of the signal of an atom
interferometer is studied theoretically. Using traditional techniques in atom
optics based on the density matrix equations in the Wigner representation, we
are able to extract the various contributions to the phase of the signal
associated with the classical motion of the atoms, the quantum correction to
this motion resulting from atomic recoil that is produced when the atoms
interact with Raman field pulses, and quantum corrections to the atomic motion
that occur in the time between the Raman field pulses. By increasing the
effective wave vector associated with the Raman field pulses using modified
field parameters, we can increase the sensitivity of the signal to the point
where the quantum corrections can be measured. The expressions that are derived
can be evaluated numerically to isolate the contribution to the signal from an
external test mass. The regions of validity of the exact and approximate
expressions are determined.Comment: 23 pages, 3 figures, 2 table
Report of conference evaluation committee
A general classification is made of a number of approaches used for the prediction of turbulent shear flows. The sensitivity of these prediction methods to parameter values and initial data are discussed in terms of variable density, pressure fluctuation, gradient diffusion, low Reynolds number, and influence of geometry
Dissipation enhanced vibrational sensing in an olfactory molecular switch
Motivated by a proposed olfactory mechanism based on a
vibrationally-activated molecular switch, we study electron transport within a
donor-acceptor pair that is coupled to a vibrational mode and embedded in a
surrounding environment. We derive a polaron master equation with which we
study the dynamics of both the electronic and vibrational degrees of freedom
beyond previously employed semiclassical (Marcus-Jortner) rate analyses. We
show: (i) that in the absence of explicit dissipation of the vibrational mode,
the semiclassical approach is generally unable to capture the dynamics
predicted by our master equation due to both its assumption of one-way
(exponential) electron transfer from donor to acceptor and its neglect of the
spectral details of the environment; (ii) that by additionally allowing strong
dissipation to act on the odorant vibrational mode we can recover exponential
electron transfer, though typically at a rate that differs from that given by
the Marcus-Jortner expression; (iii) that the ability of the molecular switch
to discriminate between the presence and absence of the odorant, and its
sensitivity to the odorant vibrational frequency, are enhanced significantly in
this strong dissipation regime, when compared to the case without mode
dissipation; and (iv) that details of the environment absent from previous
Marcus-Jortner analyses can also dramatically alter the sensitivity of the
molecular switch, in particular allowing its frequency resolution to be
improved. Our results thus demonstrate the constructive role dissipation can
play in facilitating sensitive and selective operation in molecular switch
devices, as well as the inadequacy of semiclassical rate equations in analysing
such behaviour over a wide range of parameters.Comment: 12 pages, 6 figures, close to published version, comments welcom
First determination of the content of and updated determination of the contents of and
Quantum-correlated decays collected by the CLEO-c
experiment are used to perform a first measurement of , the
fractional -even content of the self-conjugate decay , obtaining a value of . An important
input to the measurement comes from the use of
and decays to tag the signal mode. This same
technique is applied to the channels and , yielding and
, where the first uncertainty is
statistical and the second systematic. These measurements are consistent with
those of an earlier analysis, based on -eigenstate tags, and can be
combined to give values of and
. The results will enable the three modes to
be included in a model-independent manner in measurements of the unitarity
triangle angle using decays, and in time-dependent
studies of violation and mixing in the system.Comment: Minor revisions following journal acceptanc
Branching of the Falkner-Skan solutions for λ < 0
The Falkner-Skan equation f'" + ff" + λ(1 - f'^2) = 0, f(0) = f'(0) = 0, is discussed for λ < 0. Two types of problems, one with f'(∞) = 1 and another with f'(∞) = -1, are considered. For λ = 0- a close relation between these two types is found. For λ < -1 both types of problem allow multiple solutions which may be distinguished by an integer N denoting the number of zeros of f' - 1. The numerical results indicate that the solution branches with f'(∞) = 1 and those with f'(∞) = -1 tend towards a common limit curve as N increases indefinitely. Finally a periodic solution, existing for λ < -1, is presented.
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Coronary Artery Reperfusion
The effects of coronary artery reperfusion 3 hr after coronary occlusion on contractile function and the development of myocardial damage at 24 hr was studied experimentally. In 14 control and 6 reperfused dogs, relationships between epicardial ST segment elevation 15 min after coronary occlusion and myocardial creatine phosphokinase activity (CPK) and histologic appearance 24 hr later were examined. The electrocardiograms were recorded from 10 to 15 sites on the left ventricular epicardium and transmural samples for CPK and histology were obtained from the same sites where epicardial electrocardiograms had been recorded. An inverse relation existed between ST segment elevation (mv) 15 min after occlusion and log CPK activity (IU/ mg of protein) 24 hr later, log CPK = - 0.06ST + 1.26. In dogs subjected to coronary artery reperfusion, there was significantly less CPK depression (log CPK = - 0.01ST + 1.31, [P < 0.01]) than that expected from the control group. In the control group 97% of specimens showing ST segment elevations over 2 mv at 15 min showed abnormal histology 24 hr later. In contrast, in the reperfused group 43% of sites exhibiting elevated ST segment at 15 min showed abnormal histology 24 hr later. In six additional dogs it was shown that the paradoxical movement of the left ventricular wall could be reversed within 1 hr of perfusion. Therefore, by enzymatic and histologic criteria, as well as by functional assessment, coronary artery reperfusion 3 hr after occlusion resulted in salvage of myocardial tissue
Coefficient Functions and Open Charm Production in Deep Inelastic Scattering
It is shown that the problem of double counting in open charm production in
DIS can be solved by using the expression for DIS coefficient functions in
terms of 2PI diagramsComment: 11 pages, REVTeX, no figure
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Tissue factor pathway inhibitor-2 is a novel inhibitor of matrix metalloproteinases with implications for atherosclerosis
Degradation of ECM, particularly interstitial collagen, promotes plaque instability, rendering atheroma prone to rupture. Previous studies implicated matrix metalloproteinases (MMPs) in these processes, suggesting that dysregulated MMP activity, probably due to imbalance with endogenous inhibitors, promotes complications of atherosclerosis. We report here that the serine proteinase inhibitor tissue factor pathway inhibitor-2 (TFPI-2) can function as an MMP inhibitor. TFPI-2 diminished the ability of the interstitial collagenases MMP-1 and MMP-13 to degrade triple-helical collagen, the primary load-bearing molecule of the ECM within human atheroma. In addition, TFPI-2 also reduced the activity of the gelatinases MMP-2 and MMP-9. In contrast to the "classical" tissue inhibitors of MMPs (TIMPs), TFPI-2 expression in situ correlated inversely with MMP levels in human atheroma. TFPI-2 colocalized primarily with smooth muscle cells in the normal media as well as the plaque's fibrous cap. Conversely, the macrophage-enriched shoulder region, the prototypical site of matrix degradation and plaque rupture, stained only weakly for TFPI-2 but intensely for gelatinases and interstitial collagenases. Evidently, human mononuclear phagocytes, an abundant source of MMPs within human atheroma, lost their ability to express this inhibitor during differentiation in vitro. These findings establish a new, anti-inflammatory function of TFPI-2 of potential pathophysiological significance for human diseases, including atherosclerosis
Hard-scattering factorization with heavy quarks: A general treatment
A detailed proof of hard scattering factorization is given with the inclusion
of heavy quark masses. Although the proof is explicitly given for
deep-inelastic scattering, the methods apply more generally The
power-suppressed corrections to the factorization formula are uniformly
suppressed by a power of \Lambda/Q, independently of the size of heavy quark
masses, M, relative to Q.Comment: 52 pages. Version as published plus correction of misprint in Eq.
(45
First determination of the CP content of D->pi+pi-pi0 and D->K+K-pi0
Quantum-correlated psi(3770)->DDbar decays collected by the CLEO-c experiment
are used to perform first measurements of F+, the fractional CP-even content of
the self-conjugate decays D->pi+pi-pi0 and D->K+K-pi0. Values of 0.968 +/-
0.017 +/- 0.006 and 0.731 +/- 0.058 +/- 0.021 are obtained for pi+pi-pi0 and
K+K-pi0, respectively. It is demonstrated how modes of this sort can be cleanly
included in measurements of the unitarity triangle angle gamma using B+/- -> D
K+/- decays. The high CP-even content of D -> pi+pi-pi0, in particular, makes
this a promising mode for improving the precision on gamma.Comment: 18 pages, 4 figures, submitted to Phys. Lett.
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