18 research outputs found
4-(4-Fluorophenyl)-2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carbonitrile
In the molecule of the title compound, C20H13FN2O, the fluorophenyl ring is oriented at a dihedral angle of 72.76 (3)° with respect to the fused benzene ring. In the crystal structure, intermolecular N—H⋯O, C—H⋯O and C—H⋯F interactions link the molecules into chains. π–π contacts between the quinoline and benzene rings [centroid–centroid distance = 3.918 (3) Å] may further stabilize the structure. A weak C—H⋯π interaction is also present. The O atom and two of the CH2 groups of the quinoline ring system are disordered over two positions. The O atom was refined with occupancies of 0.489 (17) and 0.511 (17), while C and H atoms were refined with occupancies of 0.435 (13) and 0.565 (13)
Visible-Light-Initiated Catalyst-Free Radical Annulation Reactions of 1,6-Enynes and Aryl Sulfonyl Bromide to Assemble Sulfonation/Bromination Succinimide Derivatives
In the present study, the environment-friendly visible-light-promoted
strategy is used to perform an efficient, simple, and straightforward
photocatalytic succinimide derivative synthesis from the reaction
of 1,6-enynes and aryl sulfonyl bromide at room temperature under
air ambient conditions. This method features mild conditions, broad
substrate scope, high yields, and excellent configurational selectivity.
In addition, all the atoms of the substrates involved in the reaction
converge in the product structures, showing a high atomic economy.
Moreover, the most important characteristic of this study is that
no photocatalyst and additives are used, while the key factor that
triggers the reaction is visible light, indicating that this study
has an important practical value
Electrochemical Radical Reaction Construction of C–C Bonds: Access to 1,4-Dicarbonyl Compounds from Enol Acetates and 1,3-Diketones
As
important substrates for the construction of heterocycles, a
simple and efficient approach for synthesis of 1,4-diones is highly
desirable. In this work, novel and efficient electrochemical radical
reactions of enol acetates and 1,3-diketones have been developed to
successfully achieve 1,4-diketones under catalyst-free and oxidant-free
conditions. The wide range of substrates, good group tolerance, and
simple operation process make the approach have important practical
value. Moreover, the obtained 1,4-diketones can be easily further
transformed to pyrrole and furan derivatives