Hertz-level Measurement of the 40Ca+ 4s 2S1/2-3d 2D5/2 Clock Transition Frequency With Respect to the SI Second through GPS

We report a frequency measurement of the clock transition of a single ^40Ca^+ ion trapped and laser cooled in a miniature ring Paul trap with 10^-15 level uncertainty. In the measurement, we used an optical frequency comb referenced to a Hydrogen maser, which was calibrated to the SI second through the Global Positioning System (GPS). Two rounds of measurements were taken in May and June 2011, respectively. The frequency was measured to be 411 042 129 776 393.0(1.6) Hz with a fractional uncertainty of 3.9{\times}10^-15 in a total averaging time of > 2{\times}10^6 s within 32 days

Privatization, Public R&D Policy, and Private R&D Investment in China's Agriculture

Private R&D is a major source of innovation and productivity growth in agriculture worldwide. This paper examines trends and determinants of agricultural R&D in China. Results show that while the public sector monopolized agricultural research until recently, private agricultural R&D has grown rapidly since 2000, driven largely by agribusiness privatization. Public-sector R&D investments in basic research also encouraged private R&D research, but public investments in technology development crowded out private R&D investment. China’s private R&D investment would grow more rapidly if the government shifted public resources from technology development to basic research.Agriculture, China, Private R&D, Privatization, Public R&D, Research and Development/Tech Change/Emerging Technologies,

Scheme for sharing classical information via tripartite entangled states

We investigate schemes for quantum secret sharing and quantum dense coding via tripartite entangled states. We present a scheme for sharing classical information via entanglement swapping using two tripartite entangled GHZ states. In order to throw light upon the security affairs of the quantum dense coding protocol, we also suggest a secure quantum dense coding scheme via W state in analogy with the theory of sharing information among involved users.Comment: 4 pages, no figure. A complete rewrritten vession, accepted for publication in Chinese Physic

From insulator to quantum Hall liquid at low magnetic fields

We have performed low-temperature transport measurements on a GaAs two-dimensional electron system at low magnetic fields. Multiple temperature-independent points and accompanying oscillations are observed in the longitudinal resistivity between the low-field insulator and the quantum Hall (QH) liquid. Our results support the existence of an intermediate regime, where the amplitudes of magneto-oscillations can be well described by conventional Shubnikov-de Haas theory, between the low-field insulator and QH liquid.Comment: Magneto-oscillations governed by Shubnikov-de Haas theory are observed between the low-field insulator and quantum Hall liqui

LinearCoFold and LinearCoPartition: Linear-Time Algorithms for Secondary Structure Prediction of Interacting RNA molecules

Many ncRNAs function through RNA-RNA interactions. Fast and reliable RNA structure prediction with consideration of RNA-RNA interaction is useful. Some existing tools are less accurate due to omitting the competing of intermolecular and intramolecular base pairs, or focus more on predicting the binding region rather than predicting the complete secondary structure of two interacting strands. Vienna RNAcofold, which reduces the problem into the classical single sequence folding by concatenating two strands, scales in cubic time against the combined sequence length, and is slow for long sequences. To address these issues, we present LinearCoFold, which predicts the complete minimum free energy structure of two strands in linear runtime, and LinearCoPartition, which calculates the cofolding partition function and base pairing probabilities in linear runtime. LinearCoFold and LinearCoPartition follows the concatenation strategy of RNAcofold, but are orders of magnitude faster than RNAcofold. For example, on a sequence pair with combined length of 26,190 nt, LinearCoFold is 86.8x faster than RNAcofold MFE mode (0.6 minutes vs. 52.1 minutes), and LinearCoPartition is 642.3x faster than RNAcofold partition function mode (1.8 minutes vs. 1156.2 minutes). Different from the local algorithms, LinearCoFold and LinearCoPartition are global cofolding algorithms without restriction on base pair length. Surprisingly, LinearCoFold and LinearCoPartition's predictions have higher PPV and sensitivity of intermolecular base pairs. Furthermore, we apply LinearCoFold to predict the RNA-RNA interaction between SARS-CoV-2 gRNA and human U4 snRNA, which has been experimentally studied, and observe that LinearCoFold's prediction correlates better to the wet lab results