6,537 research outputs found
Modulation of Acupuncture on Cell Apoptosis and Autophagy
Acupuncture has been historically practiced to treat medical disorders by mechanically stimulating specific acupoints. Despite its well-documented efficacy, its biological basis largely remains elusive. Recent studies suggested that cell apoptosis and autophagy might play key roles in acupuncture therapy. Therefore, we searched PubMed, Embase, Web of Science, and China National Knowledge Infrastructure (CNKI), aiming to find the potential relationship between acupuncture and cell apoptosis and autophagy. To provide readers with objective evidence, some problems regarding the design method, acupoints selection, acupuncture intervention measure, and related diseases existing in 40 related researches were shown in this review. These findings demonstrated that acupuncture has a potential role in modulating cell apoptosis and autophagy in animal models, suggesting it as a candidate mechanism in acupuncture therapy to maintain physiologic homeostasis
Ancient Records and Modern Research on the Mechanisms of Chinese Herbal Medicines in the Treatment of Diabetes Mellitus
Over the past decades, Chinese herbal medicines (CHM) have been extensively and intensively studied through from both clinical and experimental perspectives and CHM have been proved to be effective in the treatment of diabetes mellitus (DM). This study, by searching ancient records and modern research papers, reviewed CHM in terms of their clinical application and principal mechanism in the treatment of DM. We summarized the use of CHM mentioned in 54 famous ancient materia medica monographs and searched papers on the hypoglycemic effect of several representative CHM. Main mechanisms and limitations of CHM and further research direction for DM were discussed. On the basis of the study, we were led to conclude that TCM, as a main form of complementary and alternative medicine (CAM), was well recorded in ancient literatures and has less adverse effects as shown by modern studies. The mechanisms of CHM treatment of DM are complex, multilink, and multitarget, so we should find main hypoglycemic mechanism through doing research on CHM monomer active constituents. Many CHM monomer constituents possess noteworthy hypoglycemic effects. Therefore, developing a novel natural product for DM and its complications is of much significance. It is strongly significant to pay close attention to CHM for treatment of DM and its complications
A Practical Localization Algorithm Based on Wireless Sensor Networks
Many localization algorithms and systems have been developed by means of
wireless sensor networks for both indoor and outdoor environments. To achieve
higher localization accuracy, extra hardware equipments are utilized by most of
the existing localization algorithms, which increase the cost and greatly limit
the range of location-based applications. In this paper we present a method
which can effectively meet different localization accuracy requirements of most
indoor and outdoor location services in realistic applications. Our algorithm
is composed of two phases: partition phase, in which the target region is split
into small grids and localization refinement phase in which a higher accuracy
location can be generated by applying a trick algorithm. A realistic demo
system using our algorithm has been developed to illustrate its feasibility and
availability. The results show that our algorithm can improve the localization
accuracy.Comment: IEEE/ACM Int Conf on Green Computing and Communications (GreenCom),
IEEE, Hangzhou, China, December 18-20, 201
A new species of cosmocerca (Nematoda, ascaridomorpha) from the marine toad rhinella marina (linnaeus) (anura, bufonidae) in Australia
The marine toad Rhinella marina (Linnaeus) (Anura, Bufonidae) is a notorious, exotic amphibian species in Australia. However, our present knowledge of the composition of the nematode fauna of R. marina is still not complete. In the present study, a new cosmocercid nematode, Cosmocerca multipapillata sp. nov., was described using both light and scanning electron microscopy, based on specimens collected from R. marina in Australia. Cosmocerca multipapillata sp. nov. can be easily distinguished from its congeners by the body size, the presence of lateral alae and well sclerotized gubernaculum, the number and arrangement of plectanes and rosettes and the length of spicules, oesophagus and tail
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