1,545 research outputs found
(Acetato-κO)bis(2,2′-bipyridyl-κ2 N,N′)copper(II)–ethyl sulfate–methyl sulfate (1/0.5/0.5)
In the title complex, [Cu(C2H3O2)(C10H8N2)2](CH3CH2OSO3)0.5(CH3OSO3)0.5, the CuII ion is bis-chelated by two 2,2′-bipyridine lignds and coordinated by an O atom of an acetate ligand in a CuN4O disorted square-pyramidal environment. In the structure, equal amounts of methyl sulfate and ethyl sulfate anions are disordered on the same crystallographic sites. The crystal structure is stabilized by weak intermolecular C—H⋯O interactions
PHL 6625: A Minor Merger-Associated QSO Behind NGC 247
PHL 6625 is a luminous quasi-stellar object (QSO) at z = 0.3954 located
behind the nearby galaxy NGC 247 (z = 0.0005). Hubble Space Telescope (HST)
observations revealed an arc structure associated with it. We report on
spectroscopic observations with the Very Large Telescope (VLT) and
multiwavelength observations from the radio to the X-ray band for the system,
suggesting that PHL 6625 and the arc are a close pair of merging galaxies,
instead of a strong gravitational lens system. The QSO host galaxy is estimated
to be (4-28) x 10^10 M_sun, and the mass of the companion galaxy of is
estimated to be M_* = (6.8 +/- 2.4) x 10^9 M_sun, suggesting that this is a
minor merger system. The QSO displays typical broad emission lines, from which
a black hole mass of about (2-5) x 10^8 M_sun and an Eddington ratio of about
0.01-0.05 can be inferred. The system represents an interesting and rare case
where a QSO is associated with an ongoing minor merger, analogous to Arp 142.Comment: ApJ to appea
Faster Algorithms for Bounded Knapsack and Bounded Subset Sum Via Fine-Grained Proximity Results
We investigate pseudopolynomial-time algorithms for Bounded Knapsack and
Bounded Subset Sum. Recent years have seen a growing interest in settling their
fine-grained complexity with respect to various parameters. For Bounded
Knapsack, the number of items and the maximum item weight are
two of the most natural parameters that have been studied extensively in the
literature. The previous best running time in terms of and is
[Polak, Rohwedder, Wegrzycki '21]. There is a conditional
lower bound of based on -convolution
hypothesis [Cygan, Mucha, Wegrzycki, Wlodarczyk '17]. We narrow the gap
significantly by proposing a -time algorithm.
Note that in the regime where , our algorithm runs in
time, while all the previous algorithms require
time in the worst case.
For Bounded Subset Sum, we give two algorithms running in
and time, respectively.
These results match the currently best running time for 0-1 Subset Sum. Prior
to our work, the best running times (in terms of and ) for
Bounded Subset Sum is [Polak, Rohwedder,
Wegrzycki '21] and [implied by
Bringmann '19 and Bringmann, Wellnitz '21], where refers to the
maximum multiplicity of item weights
A Nearly Quadratic-Time FPTAS for Knapsack
We investigate polynomial-time approximation schemes for the classic 0-1
knapsack problem. The previous algorithm by Deng, Jin, and Mao (SODA'23) has
approximation factor 1 + \eps with running time \widetilde{O}(n +
\frac{1}{\eps^{2.2}}). There is a lower Bound of (n +
\frac{1}{\eps})^{2-o(1)} conditioned on the hypothesis that has no
truly subquadratic algorithm. We close the gap by proposing an approximation
scheme that runs in \widetilde{O}(n + \frac{1}{\eps^2}) time
Methylenetetrahydrofolate reductase polymorphism and capecitabine-induced toxicity in patients with gastric cancer
Purpose: To evaluate the effect of methylenetetrahydrofolate reductase (MTHFR) polymorphism on toxicity in gastric cancer (GC) patients treated with capecitabine.
Methods: One hundred and twenty-six GC patients were treated with capecitabine in the study. DNA from GC patients was genotyped for MTHFR A1298C using direct sequencing. Toxicity evaluations were graded. Clinical response was assessed.
Results: In 87.3 % of the patients, capecitabine toxicity was observed. As for MTHFR A1298C polymorphism, 55.6 % patients who exhibited it were associated with reduced MTHFR activity. MTHFR A1298C was associated with capecitabine-related toxicity (p = 0.008); in addition, MTHFR A1298C was significantly associated with gastrointestinal toxicity (p = 0.026), but not with other types of toxicity.
Conclusion: The findings suggest that MTHFR A1298C may be useful for predicting toxicity in GC patients receiving capecitabine treatment, especially gastrointestinal toxicity.
Keywords: MTHFR, Polymorphism, Gastric cancer, Toxicit
Bis(2-methoxyphenolato-κ2 O,O′)copper(II)
In the title compound, [Cu(C7H7O2)2], the asymmetric unit contains one and a half molecules with the central Cu(II) atoms situated on a general position and on a centre of inversion, respectively. Both Cu(II) atoms show a similar slightly distorted square-planar coordination, resulting from four O atoms of two 2-methoxyphenolate anions
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