2,010 research outputs found

    Discussion on the teaching mode of higher vocational nursing specialty based on CDIO model

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    基于CDIO模式下高职院校护理专业教学模式的探讨是本文的研究核心。CDIO是国际高等工程教育改革的最新成果,兴起于2000年,国内高校在引入CDIO 模式改革过程中,出现一些问题或疑惑是在所难免的,所以CDIO模式是高等教育院校,尤其是高职院校教师对陈旧教学模式的一次大胆尝试。CDIO模式能够促使教师反思已固有的习惯性教学理念,从而在教学过程中改变教学方法,使教师的教学工作能力得以很大程度的提高,同时鼓励学生的学习行为趋于自主性,培养其自身的专业能力、个人发展能力、人际交往能力和系统创新能力等职业综合能力。Discussion on the teaching mode of higher vocational nursing specialty based on CDIO model is the core of this study. CDIO is the latest achievement in the reform of the international higher education of engineering and has been thrived since 2000. There are some inevitable problems when domestic universities introduced and innovated the CDIO mode. Therefore the CDIO model is a bold attempt for the institutions of higher education, especially higher vocational college teachers. The CDIO mode drives teachers to reflect on the existed teaching philosophy, and therefore enables them to change teaching methods in the teaching process and improve their teaching capacity tremendously. Meanwhile, it also encourages students to learn automatically and cultivate their comprehensive abilities such as professional capability, development capability, interpersonal skills, innovation ability, etc

    Identification of Regional Lymph Node Involvement of Colorectal Cancer by Serum SELDI Proteomic Patterns

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    Background. To explore the application of serum proteomic patterns for the preoperative detection of regional lymph node involvement of colorectal cancer (CRC). Methods. Serum samples were applied to immobilized metal affinity capture ProteinChip to generate mass spectra by Surface-Enhanced Laser Desorption/ionization Time-of-Flight Mass Spectrometry (SELDI-TOF-MS). Proteomic spectra of serum samples from 70 node-positive CRC patients and 75 age- and gender-matched node-negative CRC patients were employed as a training set, and a classification tree was generated by using Biomarker Pattern Software package. The validity of the classification tree was then challenged with a blind test set including another 65 CRC patients. Results. The software identified an average of 46 mass peaks/spectrum and 5 of the identified peaks at m/z 3,104, 3,781, 5,867, 7,970, and 9,290 were used to construct the classification tree. The classification tree separated effectively node-positive CRC patients from node-negative CRC patients, achieving a sensitivity of 94.29% and a specificity of 100.00%. The blind test challenged the model independently with a sensitivity of 91.43% a specificity of 96.67%. Conclusions. The results indicate that SELDI-TOF-MS can correctly distinguish node-positive CRC patients from node-negative ones and show great potential for preoperative screening for regional lymph node involvement of CRC

    Analysis of GT-3a identifies a distinct subgroup of trihelix DNA-binding transcription factors in Arabidopsis

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    AbstractTrihelix DNA-binding factors (or GT factors) bind to GT elements found in the promoters of many plant genes. Although the binding specificity and the transcriptional activity of some members (e.g. GT-1 and GT-2) have been studied, the regulatory function of this family of transcription factors remains largely unknown. In this work, we have characterised a new GT factor, namely GT-3a, and a closely related member, GT-3b. We show that (1) they can form either homo- or heterodimers but do not interact with GT-1; (2) they are predominantly expressed in floral buds and roots; (3) GT-3a cannot bind to the binding sites of GT-1 or GT-2, but binds to the cab2 and rbcS-1A gene promoters via the 5′-GTTAC sequence, which has been previously shown to be the core of the Site 1 type of GT elements. These results suggest that GT-3a and GT-3b belong to a distinct subgroup of GT factors and that each subgroup of GT factors binds to a functionally distinct type of cis-acting GT elements

    Gender-specific association of MSA2756G with hypertension in patients attending a health facility in Ningxia Province, China

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    Purpose: To investigate the distribution of methionine synthase A2756G (MSA2756G) in the hypertensive patients in northwest Chinese population.Methods: A total of 378 unrelated hypertensive patients attending Ningxia Peoples Hospital, Ningxia Province, China, were recruited for this study. We analyzed genotype by amplication - created restriction sites (ACRS) and polymerase chain reaction - restrict fragment length polymorphism (PCR - RFLP) in hypertensive patients, and inspected the relation of the genotype with hypertension by χ2 and t test.Results: The frequency of G allele was 10.25 % in the control group and 14.04 % in hypertension group; it was not statistically different (p > 0.05). In the male group, the frequency of allele G was 11.50 % in control group, and 8.79 % in hypertension group. There was no significant difference between control and hypertension groups (p > 0.05). In the female group, the frequency of allele G was 9.00 %, in control and 19.54 % in hypertension group (p < 0.05), while in the hypertension group, allele G was 8.79 % in males which is significantly lower (p < 0.05) than in females (19.54 %) .Conclusion: Allele G of MSA2756G is a risk factor for hypertension in female in this Chinese population of this study.Keywords: Hypertension, Methionine synthase, Polymorphism, Gender, Amplification-created restriction sites, Allele G, MSA2756

    The Study of Dynamic Monitor of Rice Drought in Jiangxi Province with Remote Sensing

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    AbstractMODIS sensor has a high temporal resolution, spectral resolution, and moderate spatial resolution. The data products are widely used in Large-scale and long period dynamic monitoring of drought. This paper focuses on characters of farming rice dominated in Jiangxi province, and analysis on remote sensing monitoring model and drought monitoring indicators which selection the MODIS data products and drought information related from 2000-2008. Established standard for classification of drought in Jiangxi province, and verified instances of 2003 drought in Jiangxi. This study may have a certain significance to agricultural drought monitoring based on rice planting in southern China, because the correspondencematch between the selected TD indices and cloud cover with precipitation and daily maximum temperature evolution curve

    1,3-Bis[5-(2-pyrid­yl)-1H-tetra­zol-1-yl]propane

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    The title compound, C15H14N10, is a multidentate ligand obtained by the reaction of 5-(2-pyrid­yl)tetra­zole with 1,3-dibromo­propane. The mol­ecule consists of two 5-(2-pyrid­yl)-1H-tetra­zol-1-yl units connected by a propyl­ene bridge in a U-like conformation. A twofold rotation axis passes through the central C atom

    AlphaPose: Whole-Body Regional Multi-Person Pose Estimation and Tracking in Real-Time

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    Accurate whole-body multi-person pose estimation and tracking is an important yet challenging topic in computer vision. To capture the subtle actions of humans for complex behavior analysis, whole-body pose estimation including the face, body, hand and foot is essential over conventional body-only pose estimation. In this paper, we present AlphaPose, a system that can perform accurate whole-body pose estimation and tracking jointly while running in realtime. To this end, we propose several new techniques: Symmetric Integral Keypoint Regression (SIKR) for fast and fine localization, Parametric Pose Non-Maximum-Suppression (P-NMS) for eliminating redundant human detections and Pose Aware Identity Embedding for jointly pose estimation and tracking. During training, we resort to Part-Guided Proposal Generator (PGPG) and multi-domain knowledge distillation to further improve the accuracy. Our method is able to localize whole-body keypoints accurately and tracks humans simultaneously given inaccurate bounding boxes and redundant detections. We show a significant improvement over current state-of-the-art methods in both speed and accuracy on COCO-wholebody, COCO, PoseTrack, and our proposed Halpe-FullBody pose estimation dataset. Our model, source codes and dataset are made publicly available at https://github.com/MVIG-SJTU/AlphaPose.Comment: Documents for AlphaPose, accepted to TPAM
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