Slow Adaptive OFDMA Systems Through Chance Constrained Programming

Adaptive OFDMA has recently been recognized as a promising technique for providing high spectral efficiency in future broadband wireless systems. The research over the last decade on adaptive OFDMA systems has focused on adapting the allocation of radio resources, such as subcarriers and power, to the instantaneous channel conditions of all users. However, such "fast" adaptation requires high computational complexity and excessive signaling overhead. This hinders the deployment of adaptive OFDMA systems worldwide. This paper proposes a slow adaptive OFDMA scheme, in which the subcarrier allocation is updated on a much slower timescale than that of the fluctuation of instantaneous channel conditions. Meanwhile, the data rate requirements of individual users are accommodated on the fast timescale with high probability, thereby meeting the requirements except occasional outage. Such an objective has a natural chance constrained programming formulation, which is known to be intractable. To circumvent this difficulty, we formulate safe tractable constraints for the problem based on recent advances in chance constrained programming. We then develop a polynomial-time algorithm for computing an optimal solution to the reformulated problem. Our results show that the proposed slow adaptation scheme drastically reduces both computational cost and control signaling overhead when compared with the conventional fast adaptive OFDMA. Our work can be viewed as an initial attempt to apply the chance constrained programming methodology to wireless system designs. Given that most wireless systems can tolerate an occasional dip in the quality of service, we hope that the proposed methodology will find further applications in wireless communications

Engineering three-dimensionally electrodeposited Si-on-Ni inverse opal structure for high volumetric capacity Li-ion microbattery anode.

Aiming at improving the volumetric capacity of nanostructured Li-ion battery anode, an electrodeposited Si-on-Ni inverse opal structure has been proposed in the present work. This type of electrode provides three-dimensional bi-continuous pathways for ion/electron transport and high surface area-to-volume ratios, and thus exhibits lower interfacial resistance, but higher effective Li ions diffusion coefficients, when compared to the Si-on-Ni nanocable array electrode of the same active material mass. As a result, improved volumetric capacities and rate capabilities have been demonstrated in the Si-on-Ni inverse opal anode. We also show that optimization of the volumetric capacities and the rate performance of the inverse opal electrode can be realized by manipulating the pore size of the Ni scaffold and the thickness of the Si deposit

Functional constituency members in Hong Kong's Legislative Council : a study of governance, legitimacy and accountability in action / y Cheung Hin Kei, Hankie, Ho Sing Yan, Simon, Li Man Pong, Charles, Tse Tsz Ying, Amy, Wong Man Ting, Mandy

published_or_final_versionPolitics and Public AdministrationMasterMaster of Public Administratio

Long-Chain Polyunsaturated Fatty Acid Concentrations in Breast Milk from Chinese Mothers: Comparison with Other Regions

Long-chain polyunsaturated fatty acids (LC-PUFA), especially linoleic acid (LA), arachidonic acid (AA), alpha- linolenic acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential to infant growth and development during early life. Up till now, there is only limited number of studies with large sample size on LC-PUFA in breast milk in China. In order to better understand the LC-PUFA levels in Chinese women, we report an analysis that included 44 studies of 3815 subjects from the latest 10-year peer-reviewed papers of breast milk studies of fatty acid profiles from China and other regions: Asia (excluding China), Europe, America and Africa. The results showed that Chinese women had significantly higher LA and ALA levels in the breast milk than European and other Asian women. The DHA level in the breast milk of Chinese women meets the Chinese and international recommended intake for young infants. This review provides comprehensive investigation on the LC-PUFA levels in the mature milk of Chinese women in most recent publications and server as a reference for further studies on human milk in China

Genome sequence and genetic linkage analysis of Shiitake mushroom _Lentinula edodes_

_Lentinula edodes_ (Shiitake/Xianggu) is an important cultivated mushroom. Understanding the genomics and functional genomics of _L. edodes_ allows us to improve its cultivation and quality. Genome sequence is a key to develop molecular genetic markers for breeding and genetic manipulation. We sequenced the genome of _L. edodes_ monokaryon L54A using Roche 454 and ABI SOLiD genome sequencing. Sequencing reads of about 1400Mb were de novo assembled into a 40.2 Mb genome sequence. We compiled the genome sequence into a searchable database with which we have been annotating the genes and analyzing the metabolic pathways. In addition, we have been using many molecular techniques to analyze genes differentially expressed during development. Gene ortholog groups of _L. edodes_ genome sequence compared across genomes of several fungi including mushrooms identified gene families unique to mushroom-forming fungi. We used a mapping population of haploid basidiospores of dikaryon L54 for genetic linkage analysis. High-quality variations such as single nucleotide polymorphisms, insertions, and deletions of the mapping population formed a high-density genetic linkage map. We compared the linkage map to the _L. edodes_ L54A genome sequence and located selected quantitative trait loci. The Shiitake community will benefit from these resources for genetic studies and breeding.
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Increased Numbers of NK Cells, NKT-Like Cells, and NK Inhibitory Receptors in Peripheral Blood of Patients with Chronic Obstructive Pulmonary Disease

T cells and B cells participate in the pathogenesis of COPD. Currently, NK cells and NKT cells have gained increasing attention. In the present study, 19 COPD patients and 12 healthy nonsmokers (HNS) were recruited, and their pulmonary function was assessed. The frequencies of CD3+ T, CD4+ T, CD8+ T, B, NK, and NKT-like cells were determined using flow cytometry. The frequencies of spontaneous and inducible IFN-γ+ or CD107a+ NK and NKT-like cells as well as activating or inhibitory receptors were also detected. The potential association of lymphocyte subsets with disease severity was further analyzed. Significantly decreased numbers of CD3+ and CD4+ T cells, and the CD4+/CD8+ ratio, but increased numbers of CD3−CD56+ NK and CD3+CD56+ NKT-like cells were observed in COPD patients compared to HNS. The frequencies of inducible IFN-γ-secreting NK and NKT-like cells were less in COPD patients. The frequencies of CD158a and CD158b on NK cells and CD158b on NKT-like cells were greater. The frequency of CD158b+ NK cells was negatively correlated with FEV1% prediction and FEV1/FVC. Our data indicate that COPD patients have immune dysfunction, and higher frequencies of inhibitory NK cells and NKT-like cells may participate in the pathogenesis of COPD

Role of Macrophage Migration Inhibitory Factor in the Proliferation of Smooth Muscle Cell in Pulmonary Hypertension

Pulmonary hypertension (PH) contributes to the mortality of patients with lung and heart diseases. However, the underlying mechanism has not been completely elucidated. Accumulating evidence suggests that inflammatory response may be involved in the pathogenesis of PH. Macrophage migration inhibitory factor (MIF) is a critical upstream inflammatory mediator which promotes a broad range of pathophysiological processes. The aim of the study was to investigate the role of MIF in the pulmonary vascular remodeling of hypoxia-induced PH. We found that MIF mRNA and protein expression was increased in the lung tissues from hypoxic pulmonary hypertensive rats. Intensive immunoreactivity for MIF was observed in smooth muscle cells of large pulmonary arteries (PAs), endothelial cells of small PAs, and inflammatory cells of hypoxic lungs. MIF participated in the hypoxia-induced PASMCs proliferation, and it could directly stimulate proliferation of these cells. MIF-induced enhanced growth of PASMCs was attenuated by MEK and JNK inhibitor. Besides, MIF antagonist ISO-1 suppressed the ERK1/2 and JNK phosphorylation induced by MIF. In conclusion, the current finding suggested that MIF may act on the proliferation of PASMCs through the activation of the ERK1/2 and JNK pathways, which contributes to hypoxic pulmonary hypertension