1 research outputs found
Ceric Ammonium Nitrate (CAN) Catalyzed Modification of Ketones <i>via</i> Two C–C Bond Cleavages with the Retention of the Oxo-Group
A simple ceric ammonium nitrate (CAN)
catalyzed functionalization
of ketones through double C–C bond cleavage strategy has been
disclosed. This reaction provides a mild, practical method toward
carbamoyl azides, which are versatile intermediates and building blocks
in organic synthesis. Based on relevant mechanistic studies, a unique
and plausible C–C bond and N–O bond cleavage process
is proposed, where the oxyamination intermediate plays an important
role in this reaction