A text-based approach to the ImageCLEF 2010 photo annotation task

The challenges of searching the increasingly large collections of digital images which are appearing in many places mean that automated annotation of images is becoming an important task. We describe our participation in the ImageCLEF 2010 Visual Concept Detection and Annotation Task. Our approach used only the textual features (Flickr user tags and EXIF information) to perform the automatic annotation. Our approach was to explore the use of different techniques to improve the results of textual annotation. We identify the drawbacks of our approach and how these might be addressed and optimized in further work

Dual-Topology Hamiltonian-Replica-Exchange Overlap Histogramming Method to Calculate Relative Free Energy Difference in Rough Energy Landscape

A novel overlap histogramming method based on Dual-Topology Hamiltonian-Replica-Exchange simulation technique is presented to efficiently calculate relative free energy difference in rough energy landscape, in which multiple conformers coexist and are separated by large energy barriers. The proposed method is based on the realization that both DT-HERM exchange efficiency and confidence of free energy determination in overlap histogramming method depend on the same criteria: neighboring states' energy derivative distribution overlap. In this paper, we demonstrate this new methodology by calculating free energy difference between amino acids: Leucine and Asparagine, which is an identified chanllenging system for free energy simulations.Comment: 14 pages with 4 figure