Nonlocal effective medium analysis in symmetric metal-dielectric multilayer metamaterials

The optical nonlocality in symmetric metal-dielectric multilayer metamaterials is theoretically and experimentally investigated with respect to transverse-magnetic-polarized incident light. A nonlocal effective medium theory is derived from the transfer-matrix method to determine the nonlocal effective permittivity depending on both the frequency and wave vector in a symmetric metal-dielectric multilayer stack. In contrast to the local effective medium theory, our proposed nonlocal effective medium theory can accurately predict measured incident angle-dependent reflection spectra from a fabricated multilayer stack and provide nonlocal dispersion relations. Moreover, the bulk plasmon polaritons with large wave vectors supported in the multilayer stack are also investigated with the nonlocal effective medium theory through the analysis of the dispersion relation and eigenmode.Comment: 21 pages, 7 figure

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti.

The development of CRISPR/Cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. In general, in vivo germline expression of Cas9 results in substantially higher activity than embryonic injection. However, no transgenic lines expressing Cas9 have been developed for the major mosquito disease vector Aedes aegypti Here, we describe the generation of multiple stable, transgenic Ae. aegypti strains expressing Cas9 in the germline, resulting in dramatic improvements in both the consistency and efficiency of genome modifications using CRISPR. Using these strains, we disrupted numerous genes important for normal morphological development, and even generated triple mutants from a single injection. We have also managed to increase the rates of homology-directed repair by more than an order of magnitude. Given the exceptional mutagenic efficiency and specificity of the Cas9 strains we engineered, they can be used for high-throughput reverse genetic screens to help functionally annotate the Ae. aegypti genome. Additionally, these strains represent a step toward the development of novel population control technologies targeting Ae. aegypti that rely on Cas9-based gene drives

2MASS J18082002-5104378: The brightest (V=11.9) ultra metal-poor star

Context. The most primitive metal-poor stars are important for studying the conditions of the early galaxy and are also relevant to big bang nucleosynthesis. Aims. Our objective is to find the brightest (V<14) most metal-poor stars. Methods. Candidates were selected using a new method, which is based on the mismatch between spectral types derived from colors and observed spectral types. They were observed first at low resolution with EFOSC2 at the NTT/ESO to obtain an initial set of stellar parameters. The most promising candidate, 2MASS J18082002-5104378 (V=11.9), was observed at high resolution (R=50 000) with UVES at the VLT/ESO, and a standard abundance analysis was performed. Results. We found that 2MASS J18082002-5104378 is an ultra metal-poor star with stellar parameters Teff = 5440 K, log g = 3.0 dex, vt = 1.5 km/s, [Fe/H] = -4.1 dex. The star has [C/Fe]<+0.9 in a 1D analysis, or [C/Fe]<=+0.5 if 3D effects are considered; its abundance pattern is typical of normal (non-CEMP) ultra metal-poor stars. Interestingly, the star has a binary companion. Conclusions. 2MASS J1808-5104 is the brightest (V=11.9) metal-poor star of its category, and it could be studied further with even higher S/N spectroscopy to determine additional chemical abundances, thus providing important constraints to the early chemical evolution of our Galaxy.Comment: A&A Letter