"Western imitation" in modern China's urban planning practice between the Late Qing Dynasty and the Early Republic of China (1860-1927)

At the Late Qing Dynasty and the Early Republic of China, the ancient Chinese city was gradually transformed into a form that closes to a city with modern significance in terms of nature, the concept of construction, the management system and the spatial structure. Since the Western powers had previously dominated the global capital trade model and implemented the urban planning and construction paradigm, most of the modern Chinese learned and imitated the western models when they re-planned the original Chinese city areas. From the main source of imitation, it contains three categories: the concession, Japan, Europe and the United States. From the practitioner of imitation, most of them are politicians, social reformers, intellectuals with western culture and overseas Chinese with advanced notions. Their understanding and longing for the western urban planning laid the foundation of the transformation of China's modern urban planning. Based on relevant historical materials and existing researching literature, this paper analyses the process of understanding, imitating and implementing in modern China’s urban planning practice between 1860-1927 so as to make it clear that the particularity and universality in the birth and formation of modern Chinese urban planning

Vector and Spinor Decomposition of SU(2) Gauge Potential, their quivalence and Knot Structure in SU(2) Chern-Simons Theory

In this paper, spinor and vector decomposition of SU(2) gauge potential are presented and their equivalence is constructed using a simply proposal. We also obtain the action of Faddeev nonlinear O(3) sigma model from the SU(2) massive gauge field theory which is proposed according to the gauge invariant principle. At last, the knot structure in SU(2) Chern-Simons filed theory is discussed in terms of the $\phi$--mapping topological current theory. The topological charge of the knot is characterized by the Hopf indices and the Brouwer degrees of $\phi$-mapping.Comment: 10 pages, ni figur

Inner topological structure of Hopf invariant

In light of $\phi$-mapping topological current theory, the inner topological structure of Hopf invariant is investigated. It is revealed that Hopf invariant is just the winding number of Gauss mapping. According to the inner structure of topological current, a precise expression for Hopf invariant is also presented. It is the total sum of all the self-linking and all the linking numbers of the knot family.Comment: 13pages, no figure. Accepted by J.Math.Phy

An Artifact in Intracellular Cytokine Staining for Studying T Cell Responses and Its Alleviation.

Intracellular cytokine staining (ICS) is a widely employed ex vivo method for quantitative determination of the activation status of immune cells, most often applied to T cells. ICS test samples are commonly prepared from animal or human tissues as unpurified cell mixtures, and cell-specific cytokine signals are subsequently discriminated by gating strategies using flow cytometry. Here, we show that when ICS samples contain Ly6G+ neutrophils, neutrophils are ex vivo activated by an ICS reagent - phorbol myristate acetate (PMA) - which leads to hydrogen peroxide (H2O2) release and death of cytokine-expressing T cells. This artifact is likely to result in overinterpretation of the degree of T cell suppression, misleading immunological research related to cancer, infection, and inflammation. We accordingly devised easily implementable improvements to the ICS method and propose alternative methods for assessing or confirming cellular cytokine expression

Intermittent High Glucose Enhances Apoptosis in INS-1 Cells

To investigate the effect of intermittent high glucose (IHG) and sustained high glucose (SHG) on inducing β-cell apoptosis and the potential involved mechanisms, INS-1 beta cells were incubated for 72 h in the medium containing different glucose concentrations: control (5.5 mmol/L), SHG (33.3 mmol/L), and IHG (5.5 mmol/L and 33.3 mmol/L glucose alternating every 12 h). Cell viability, apoptosis rate, and oxidative-stress markers were determined. The results showed that the apoptosis induced by IHG was more obvious than that by SHG. Simultaneously, the intracellular level of oxidative stress was more significantly increased in INS-1 cells exposed to IHG. These findings suggest that intermittent high glucose could be more deleterious to β-cell than a constant high concentration of glucose, this may be due to the aggravation of oxidative stress triggered by intermittent high glucose