Confinement Effects on the Crystalline Features of Poly(9,9-dioctylfluorene)

Typical device architectures in polymer-based optoelectronic devices, such as field effect transistors organic light emitting diodes and photovoltaic cells include sub-100 nm semiconducting polymer thin-film active layers, whose microstructure is likely to be subject to finite-size effects. The aim of this study was to investigate effect of the two-dimensional spatial confinement on the internal structure of the semiconducting polymer poly(9,9-dioctylfluorene) (PFO). PFO melts were confined inside the cylindrical nanopores of anodic aluminium oxide (AAO) templates and crystallized via two crystallization strategies, namely, in the presence or in the absence of a surface bulk reservoir located at the template surface. We show that highly textured semiconducting nanowires with tuneable crystal orientation can be thus produced. Moreover, our results indicate that employing the appropriate crystallization conditions extended-chain crystals can be formed in confinement. The results presented here demonstrate the simple fabrication and crystal engineering of ordered arrays of PFO nanowires; a system with potential applications in devices where anisotropic optical properties are required, such as polarized electroluminescence, waveguiding, optical switching, lasing, etc

Reevaluation of the cox1 group I intron in Araceae and angiosperms indicates a history dominated by loss rather than horizontal transfer

The origin and modes of transmission of introns remain matters of much debate. Previous studies of the group I intron in the angiosperm cox1 gene inferred frequent angiosperm-to-angiosperm horizontal transmission of the intron from apparent incongruence between intron phylogenies and angiosperm phylogenies, patchy distribution of the intron among angiosperms, and differences between cox1 exonic coconversion tracts (the first 22 nt downstream of where the intron inserted). We analyzed the cox1 gene in 179 angiosperms, 110 of them containing the intron (intron+) and 69 lacking it (intron-). Our taxon sampling in Araceae is especially dense to test hypotheses about vertical and horizontal intron transmission put forward by Cho and Palmer (1999. Multiple acquisitions via horizontal transfer of a group I intron in the mitochondrial coxl gene during evolution of the Araceae family. Mol Biol Evol. 16:1155–1165). Maximum likelihood trees of Araceae cox1 introns, and also of all angiosperm cox1 introns, are largely congruent with known phylogenetic relationships in these taxa. The exceptions can be explained by low signal in the intron and long-branch attraction among a few taxa with high mitochondrial substitution rates. Analysis of the 179 coconversion tracts reveals 20 types of tracts (11 of them only found in single species, all involving silent substitutions). The distribution of these tracts on the angiosperm phylogeny shows a common ancestral type, characterizing most intron+ and some intron- angiosperms, and several derivative tract types arising from gradual back mutation of the coconverted nucleotides. Molecular clock dating of small intron+ and intron- sister clades suggests that coconversion tracts have persisted for 70 Myr in Araceae, whose cox1 sequences evolve comparatively slowly. Sequence similarity among the 110 introns ranges from 91% to identical, whereas putative homologs from fungi are highly different, but sampling in fungi is still sparse. Together, these results suggest that the cox1 intron entered angiosperms once, has largely or entirely been transmitted vertically, and has been lost numerous times, with coconversion tract footprints providing unreliable signal of former intron presence

Weaving Equity into Infrastructure Resilience Research and Practice: A Decadal Review and Future Directions

After about a decade of research in this domain, what is missing is a systematic overview of the research agenda across different infrastructures and hazards. It is now imperative to evaluate the current progress and gaps. This paper presents a systematic review of equity literature on disrupted infrastructure during a natural hazard event. Following a systematic review protocol, we collected, screened, and evaluated almost 3,000 studies. Our analysis focuses on the intersection within the dimensions of the eight-dimensional assessment framework that distinguishes focus of the study, methodological approaches, and equity dimensions (distributional-demographic, distributional-spatial, procedural, and capacity equity). To conceptualize the intersection of the different dimensions of equity, we refer to pathways, which identify how equity is constructed, analyzed, and used. Significant findings show that (1) the interest in equity in infrastructure resilience has exponentially increased, (2) the majority of studies are in the US and by extension in the global north, (3) most data collection use descriptive and open-data and none of the international studies use location-intelligence data. The most prominent equity conceptualization is distributional equity, such as the disproportionate impacts to vulnerable populations and spaces. The most common pathways to study equity connect distributional equity to the infrastructure's power, water, and transportation in response to flooding and hurricane storms. Other equity concepts or pathways, such as connections of equity to decision-making and building household capacity, remain understudied. Future research directions include quantifying the social costs of infrastructure disruptions and better integration of equity into resilience decision-making.Comment: 37 pages, 11 figures, 2 table

Detecting Early-warning signals in Time Series of Visits to Points of Interests to Examine Population Response to COVID -19 Pandemic

The objective of this paper is to examine population response to COVID-19 and associated policy interventions through detecting early-warning signals in time series of visits to points of interest (POIs). Complex systems, such as cities, demonstrate early-warning signals when they approach phase transitions responding to external perturbation, including crises, policy changes, and human behavior changes. In urban systems, population visits to POIs represent a state in the complex systems that are cities. These states may undergo phase transitions due to population response to pandemic risks and intervention policies. In this study, we conducted early-warning signal detection on population visits to POIs to examine population response to pandemic risks. We examined two early-warning signals, the increase of autocorrelation at-lag-1 and standard deviation, in time series of population visits to POIs in 17 metropolitan cities in the United States of America. The results show that: (1) early-warning signals for population response to COVID-19 were detected between February 14 and March 11, 2020 in 17 cities; (2) detected population response had started prior to shelter-in-place orders in 17 cities; (3) early-warning signals detected from the essential POIs visits appeared earlier than those from non-essential POIs; and 4) longer time lags between detected population response and shelter-in-place orders led to a less decrease in POI visits. The results show the importance of detecting early-warning signals during crises in cities as complex systems. Early-warning signals could provide important insights regarding the timing and extent of population response to crises to inform policy makers

Towards a First-Person Perspective Mixed Reality Guidance System for Needle Interventions

While ultrasound (US) guidance has been used during central venous catheterization to reduce complications, including the puncturing of arteries, the rate of such problems remains non-negligible. To further reduce complication rates, mixed-reality systems have been proposed as part of the user interface for such procedures. We demonstrate the use of a surgical navigation system that renders a calibrated US image, and the needle and its trajectory, in a common frame of reference. We compare the effectiveness of this system, whereby images are rendered on a planar monitor and within a head-mounted display (HMD), to the standard-of-care US-only approach, via a phantom-based user study that recruited 31 expert clinicians and 20 medical students. These users performed needle-insertions into a phantom under the three modes of visualization. The success rates were significantly improved under HMD-guidance as compared to US-guidance, for both expert clinicians (94% vs. 70%) and medical students (70% vs. 25%). Users more consistently positioned their needle closer to the center of the vessel’s lumen under HMD-guidance compared to US-guidance. The performance of the clinicians when interacting with this monitor system was comparable to using US-only guidance, with no significant difference being observed across any metrics. The results suggest that the use of an HMD to align the clinician’s visual and motor fields promotes successful needle guidance, highlighting the importance of continued HMD-guidance research