The Ultrasonic/Shear-Force Microscope: A Metrology Tool for Surface Science and Technology

This paper describes recent results obtained with the Ultrasonic/Shear-Force Microscope (SUNM), an analytical tool suitable for investigating the quite different dynamic displayed by fluid-like films when subjected to mesoscopic confinement and while in intimate contact with two sliding solid boundaries. The SUNM uses two sensory modules to concurrently but independently monitor the effects that fluid-mediated interactions exert on two sliding bodies: the microscope’s sharp probe (attached to a piezoelectric sensor) and the analyzed sample (attached to an ultrasonic transducer). This dual capability allows correlating the fluid-like film’s viscoelastic properties with changes in the probe’s resonance frequency and the generation of sound. A detailed monitoring of sliding friction by ultrasonic means and with nanometer resolution is unprecedented, which opens potential uses of the versatile microscope as a surface and subsurface material characterization tool. As a surface metrology tool, the SUNM presents a potential impact in diverse areas ranging from fundamental studies of nanotribology, confinement-driven solid to liquid phase transformation of polymer films, characterization of industrial lubricants, and the study of elastic properties of bio-membranes. As a sub-surface metrology tool, the SUNM can be used in the investigation of the elastic properties of low- and high-k dielectric materials, piezoelectric and ferroelectric films, as well as quality control in the construction of micro- and nano-fluidics devices

Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.

Type IIA topoisomerases (Top2s) manipulate the handedness of DNA crossovers by introducing a transient and protein-linked double-strand break in one DNA duplex, termed the DNA-gate, whose opening allows another DNA segment to be transported through to change the DNA topology. Despite the central importance of this gate-opening event to Top2 function, the DNA-gate in all reported structures of Top2-DNA complexes is in the closed state. Here we present the crystal structure of a human Top2 DNA-gate in an open conformation, which not only reveals structural characteristics of its DNA-conducting path, but also uncovers unexpected yet functionally significant conformational changes associated with gate-opening. This structure further implicates Top2's preference for a left-handed DNA braid and allows the construction of a model representing the initial entry of another DNA duplex into the DNA-gate. Steered molecular dynamics calculations suggests the Top2-catalyzed DNA passage may be achieved by a rocker-switch-type movement of the DNA-gate

Phase Change Observed in Ultrathin Ba0.5Sr0.5TiO3 Films by in-situ Resonant Photoemission Spectroscopy

Epitaxial Ba0.5Sr0.5TiO3 thin films were prepared on Nb-doped SrTiO3 (100)substrates by the pulsed laser deposition technique, and were studied by measuring the Ti 2p - 3d resonant photoemission spectra in the valence-band region as a function of film thickness, both at room temperature and low temperature. Our results demonstrated an abrupt variation in the spectral structures between 2.8 nm (~7 monolayers) and 2.0 nm (~5 monolayers) Ba0.5Sr0.5TiO3 films, suggesting that there exists a critical thickness for phase change in the range of 2.0 nm to 2.8 nm. This may be ascribed mainly to the intrinsic size effects.Comment: 13 pages, 4 figure

Determination of the HQET Parameters from the B→XsγB \to X_s\gamma Decay

We combine the resummations for radiative corrections and for the heavy quark expansion to study the inclusive radiative decay $B \to X_s\gamma$. The infrared renormalon ambiguity is also taken into account. Including both theoretical and experimental uncertainties, we determine the allowed domain for the HQET parameters ${\bar \Lambda}$ and $\lambda_1$ centered at ${\bar \Lambda}=0.65$ GeV and $\lambda_1=-0.71$ GeV$^2$.Comment: IR renormalon ambiguity is include

Applicability of Perturbative QCD to B→DB\to D Decays

We examine the applicability of perturbative QCD to $B$ meson decays into $D$ mesons. We find that the perturbative QCD formalism, which includes Sudakov effects at intermediate energy scales, is applicable to the semi-leptonic decay $B\to D l\nu$, when the $D$ meson recoils fast. Following this conclusion, we analyze the two-body non-leptonic decays $B\to D\pi$ and $B\to DD_s$. By comparing our predictions with experimental data, we extract the matrix element $|V_{cb}|=0.044$.Comment: 18 pages in Latex, figures are available upon reques