13 research outputs found
New Classes of Partial Geometries and Their Associated LDPC Codes
The use of partial geometries to construct parity-check matrices for LDPC
codes has resulted in the design of successful codes with a probability of
error close to the Shannon capacity at bit error rates down to . Such
considerations have motivated this further investigation. A new and simple
construction of a type of partial geometries with quasi-cyclic structure is
given and their properties are investigated. The trapping sets of the partial
geometry codes were considered previously using the geometric aspects of the
underlying structure to derive information on the size of allowable trapping
sets. This topic is further considered here. Finally, there is a natural
relationship between partial geometries and strongly regular graphs. The
eigenvalues of the adjacency matrices of such graphs are well known and it is
of interest to determine if any of the Tanner graphs derived from the partial
geometries are good expanders for certain parameter sets, since it can be
argued that codes with good geometric and expansion properties might perform
well under message-passing decoding.Comment: 34 pages with single column, 6 figure
Antihyperglycemic and antihyperlipidemic action of cinnamaldehyde in C57blks/j Db/db mice
AbstractObjectiveTo investigate the effects of cinnamaldehyde (CA), an active and major compound in cinnamon, on glucose metabolism and insulin resistance in C57BLKS/J db/db mice.MethodsSixteen male C57BLKS db/db mice were randomly divided into control and CA treatment groups. CA was given (20 mg · kg−1 · day−1, p. o.) for 4 weeks. Pure water was given to control and db/+ mice. Subsequently, the levels of fasting blood glucose (FBG), fasting serum insulin, triglyeride, cholesterol, low-density lipoprotein -cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and free fatty acids (FFA), as well as the mRNA content of adiponectin and tumor necrosis factor (TNF)-α in adipose tissue, glucose transporter type 4 (GLUT-4) in skeletal muscle, and protein expressions of Akt, phospho-Akt (Thr308), AMPKα, phospho-AMPKα (Thr172) in skeletal muscle were measured.Results1) CA decreased serum levels of FBG and insulin as well as body weight in db/db mice; 2) CA increased serum HDL-C levels; 3) CA significantly decreased the mRNA expression of TNF-α in adipose tissue and upregulated mRNA expression of GLUT-4 in skeletal muscle; 4) protein expression of p-Akt was increased in CA-treated mice, but Akt, AMPKα and p-AMPKα showed no change.ConclusionCA has antihyperglycemic and antihyperlipidemic actions in db/db mice and could be useful in the treatment of type-2 diabetes
Recommended from our members
New Classes of Partial Geometries and Their Associated LDPC Codes
The use of partial geometries to construct parity-check matrices for LDPC codes has
resulted in the design of successful codes with a probability of error close to the Shannon
capacity at bit error rates down to . Such considerations have motivated this
further investigation. A new and simple construction of a type of partial geometries with
quasi-cyclic structure is given and their properties are investigated. The trapping sets of
the partial geometry codes were considered previously using the geometric aspects of the
underlying structure to derive information on the size of allowable trapping sets. This
topic is further considered here. Finally, there is a natural relationship between partial
geometries and strongly regular graphs. The eigenvalues of the adjacency matrices of such
graphs are well known and it is of interest to determine if any of the Tanner graphs
derived from the partial geometries are good expanders for certain parameter sets, since it
can be argued that codes with good geometric and expansion properties might perform well
under message-passing decoding
Decoding of quasi-cyclic LDPC codes with section-wise cyclic structure
Abstract—Presented in this paper is a reduced-complexity iterative decoding scheme for quasi-cyclic (QC) LDPC codes. This decoding scheme is devised based on the section-wise cyclic structure of the parity-check matrix of a QC-LDPC code. Using this decoding scheme, the hardware implementation complexity of a QC-LDPC decoder can be significantly reduced without performance degradation. A high-rate QC-LDPC code that can achieve a very low error-rate without a visible error-floor is used to demonstrate the effectiveness of the proposed decoding scheme. Also presented in this paper are two other high-rate QC-LDPC codes and a method for constructing rate- 1 2 QC-LDPC codes whose Tanner graphs have girth 8. All the codes constructed perform well with low error-floor using the proposed decoding scheme. I
Recommended from our members
Quasi-Cyclic LDPC Codes with Parity-Check Matrices of Column Weight Two or More for Correcting Phased Bursts of Erasures
In his pioneering work on LDPC codes, Gallager dismissed codes with parity-check matrices of weight two after proving that their minimum Hamming distances grow at most logarithmically with their code lengths. In spite of their poor minimum Hamming distances, it is shown that quasi-cyclic LDPC codes with parity-check matrices of column weight two have good capability to correct phased bursts of erasures which may not be surpassed by using quasi-cyclic LDPC codes with parity-check matrices of column weight three or more. By modifying the parity-check matrices of column weight two and globally coupling them, the erasure correcting capability can be further enhanced. Quasi-cyclic LDPC codes with parity-check matrices of column weight three or more that can correct phased bursts of erasures and perform well over the AWGN channel are also considered. Examples of such codes based on Reed-Solomon and Gabidulin codes are presented.Division of Electrical, Communications and Cyber SystemsThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
Metabolite Profiles, Bioactivity, and HPLC Fingerprint of Different Varieties of Eucommia ulmoides Oliv.: Towards the Utilization of Medicinal and Commercial Chinese Endemic Tree
Eucommia ulmoides Oliv. is widely regarded in China as a precious medicinal and commercial endemic tree. Due to cross-breeding or natural variation of E. ulmoides, the metabolite composition may vary significantly, making control of the medical quality difficult. In order to improve the rational development and utilization, the quality of seven varieties of E. ulmoides were evaluated based on metabolite profiles (total phenolic, total flavonoid, gutta-percha, aucubin, geniposidic acid, chlorogenic acid, geniposide, pinoresinol diglucoside, rutin, hyperoside, and astragalin), bioactivities (in vitro, in vivo antioxidant activities, and antibacterial activities) and HPLC fingerprint combined with chemometrics analysis. On this basis, the differences of medicinal parts (leaf and bark) were further carried out. For the traditional use of bark, Purple-leaf E. ulmoides was the most suitable. For the use of leaf, Qinzhong 1 and Purple-leaf E. ulmoides were appropriate. HPLC fingerprint analysis showed that significant differences in metabolite profiles exist among seven varieties of E. ulmoides. Combined with chemometrics analysis, seven varieties of E. ulmoides were divided into three groups from the use of leaf and bark. The analysis not only evaluated quality of seven varieties of E. ulmoides, but also could distinguish different varieties and different regions of origin. The results can provide theoretical basis for E. ulmoides resources utilization and cultivation of fine varieties
Lipopolysaccharide Enhances Tanshinone Biosynthesis via a Ca2+-Dependent Manner in Salvia miltiorrhiza Hairy Roots
Tanshinones, the major bioactive components in Salvia miltiorrhiza Bunge (Danshen), are synthesized via the mevalonic acid (MVA) pathway or the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway and the downstream biosynthesis pathway. In this study, the bacterial component lipopolysaccharide (LPS) was utilized as a novel elicitor to induce the wild type hairy roots of S. miltiorrhiza. HPLC analysis revealed that LPS treatment resulted in a significant accumulation of cryptotanshinone (CT) and dihydrotanshinone I (DTI). qRT-PCR analysis confirmed that biosynthesis genes such as SmAACT and SmHMGS from the MVA pathway, SmDXS and SmHDR from the MEP pathway, and SmCPS, SmKSL and SmCYP76AH1 from the downstream pathway were markedly upregulated by LPS in a time-dependent manner. Furthermore, transcription factors SmWRKY1 and SmWRKY2, which can activate the expression of SmDXR, SmDXS and SmCPS, were also increased by LPS. Since Ca2+ signaling is essential for the LPS-triggered immune response, Ca2+ channel blocker LaCl3 and CaM antagonist W-7 were used to investigate the role of Ca2+ signaling in tanshinone biosynthesis. HPLC analysis demonstrated that both LaCl3 and W-7 diminished LPS-induced tanshinone accumulation. The downstream biosynthesis genes including SmCPS and SmCYP76AH1 were especially regulated by Ca2+ signaling. To summarize, LPS enhances tanshinone biosynthesis through SmWRKY1- and SmWRKY2-regulated pathways relying on Ca2+ signaling. Ca2+ signal transduction plays a key role in regulating tanshinone biosynthesis in S. miltiorrhiza
Changes in Fruit Quality Phytochemicals of Late-Mature Peach ‘Yonglian No.1’ during Storage
In this study, the changes in quality parameters and sensory-influencing parameters from the peel, red flesh, and white flesh of ‘Yonglian No.1’ peach fruits were analyzed during cold storage. The results indicated that the contents of total soluble solids (TSS), soluble sugar, organic acid, vitamin C, total anthocyanin, phenol, and flavonoids, as well as the good fruit rate varied depending on the storage stages and storage treatments. The peach fruits in MAP stored for 50 days had favorable exterior qualities, a good fruit rate of 100%, and a higher content of total soluble solids (TSS) at 12.6%. MAP was significantly effective at maintaining fruit firmness, the content of TSS, soluble sugar, organic acid, vitamin C, total anthocyanin, phenol, and flavonoids. Among the derivatives of anthocyanin, both cyanidin and pelargonidin were found in the peel, with a content of 33.45 mg/kg FW and 1.82 mg/kg FW, respectively. However, cyanidin was detected in the flesh with a content of 40.42 mg/kg FW. In the present work, the differences regarding phytochemical profiles and physical properties were mainly correlated with the storage stages and storage treatments of peach fruit. ‘Yonglian No.1’ had higher levels of health-promoting compounds during storage and maintained favorable quality