Topological Transformation and Free-Space Transport of Photonic Hopfions

Structured light fields embody strong spatial variations of polarisation, phase and amplitude. Understanding, characterization and exploitation of such fields can be achieved through their topological properties. Three-dimensional (3D) topological solitons, such as hopfions, are 3D localized continuous field configurations with nontrivial particle-like structures, that exhibit a host of important topologically protected properties. Here, we propose and demonstrate photonic counterparts of hopfions with exact characteristics of Hopf fibration, Hopf index, and Hopf mapping from real-space vector beams to homotopic hyperspheres representing polarisation states. We experimentally generate photonic hopfions with on-demand high-order Hopf indices and independently controlled topological textures, including N\'eel-, Bloch-, and anti-skyrmionic types. We also demonstrate a robust free-space transport of photonic hopfions, thus, showing potential of hopfions for developing optical topological informatics and communications

The Influence of ENSO on the Long‐Term Water Storage Anomalies in the Middle‐Lower Reaches of the Yangtze River Basin: Evaluation and Analysis

Recent extreme events in the Middle‐Lower reaches of the Yangtze River basin (MLYRB) are proven to be possibly linked to the El Niño‐Southern Oscillation (ENSO) events as indicated by terrestrial water storage anomaly (TWSA). But the relatively short observation time of Gravity Recovery and Climate Experiment series missions (2002–2017; 2018–present) affects the robustness of the evaluation of TWSA. Here, the applicability of four long‐term TWSA data sets (since 1979) in the MLYRB is evaluated first using an evaluation framework including two completely independent tests. After selecting the optimal one, we investigate the effects of ENSO on TWSA in the MLYRB at the basin, subbasin, and grid cell scales, respectively. Results show that ENSO, especially the Eastern Pacific type ENSO has had a significant impact on TWSA variations in the MLYRB and its two subbasins (the Dongting Lake basin and the Poyang Lake basin) since 1979 with correlation coefficients at 0.56–0.65 and time lags at 5–6 months. However, TWSAs in the other two subbasins (the Hanjiang River basin and the Mainstream River basin) have almost no correlation with ENSO. Further analysis reveals that compared with human activity that has a limited impact on TWSA, precipitation is one of the key inducements for regional water storage changes in these two subbasins, and the no correlation between ENSO and TWSA is mainly caused by the weak link between ENSO and precipitation

The diagnostic value of blood metagenomic next-generation sequencing in patients with acute hematogenous osteomyelitis

AimsThis study aims to evaluate the diagnostic value of blood metagenomic next-generation sequencing (mNGS) in detecting pathogens from patients clinically diagnosed as acute hematogenous osteomyelitis (AHO).MethodsThis retrospective study enrolled 66 patients with AHO. The test results of mNGS and bacterial culture on different samples, including blood and puncture fluid samples, from patients with AHO were compared to explore the diagnostic value of blood mNGS. Besides, this study also explored the efficacy of blood mNGS in decision making for antibiotic administration and analyzed the factors associated with the positive result of blood mNGS.ResultsThe most common causative pathogens were Staphylococcus and Streptococcus. The sensitivity of blood mNGS (77.3%) was higher than that of blood culture (42.4%) (P<0.001), while the turnaround time of blood mNGS (2.1 ± 0.4 d) is much less than that of blood culture (6.0 ± 2.1 d) (P<0.001). Besides, the sensitivity of blood mNGS tests (77.3%) was slightly lower than that of puncture fluid mNGS (89.4%). Furthermore, detection comparison at pathogen level unravels that blood mNGS might be suitable for diagnosing AHO caused by common pathogens, while puncture fluid mNGS could be considered as preferred examination in diagnosing AHO caused by uncommon pathogens. Finally, three independent factors associated with the true positive result of blood mNGS in patients with AHO were identified, including Gram-positive pathogens (OR=24.4, 95% CI = 1.4-421.0 for Staphylococcus; OR=14.9, 95%CI= 1.6-136.1 for other Gram-positive bacteria), body temperature at sampling time (OR=8.2, 95% CI = 0.6-107.3 for body temperature of >38.5°C; OR=17.2, 95% CI = 2.0-149.1 for patients who were chilling), and no use of antibiotics before sampling (OR=8.9, 95% CI =1.4-59.0).ConclusionThis is the first report on evaluating and emphasizing the importance of blood mNGS in diagnosing AHO. Blood sample might be an alternative sample for puncture fluid for mNGS, and its extensive application in diagnosing AHO could be expected

Single-Shot Full Characterization of the Spatial Wavefunction of Light Fields via Stokes Tomography

Since the diffraction behavior of a light field is fully determined by its spatial wavefunction, i.e., its spatial complex amplitude (SCA), full characterization of spatial wavefunction plays a vital role in modern optics from both the fundamental and applied aspects. In this work, we present a novel “complex-amplitude profiler” based on spatial Stokes tomography with the capability to fully determine the SCA of a light field in a single shot with high precision and resolution. The SCA slice observed at any propagation plane provides complete information about the light field, thus allowing us to further retrieve the complete beam structure in the 3D space as well as the exact modal constitution in terms of spatial degrees of freedom. The principle demonstrated here provides an important advancement for the full characterization of light beams with a broad spectrum of potential applications in various areas of optics, especially for the growing field of structured light

The marriage of AIE and interface engineering: convenient synthesis and enhanced photovoltaic performance

As a promising option out of all of the well-recognized candidates that have been developed to solve the coming energy crisis, polymer solar cells (PSCs) are a kind of competitive clean energy source. However, as a convenient and efficient method to improve the efficiency of PSCs, the inherent mechanism of the interfacial modification was still not so clear, and interfacial materials constructed with new units were limited to a large degree. Here we present a new kind of interfacial material consisting of AIE units for the first time, with an efficiency of 8.94% being achieved by inserting TPE-2 as a cathode interlayer. This is a relatively high PCE for PC71BM: PTB7-based conventional PSCs with a single-junction structure. Different measurements, including TEM, AFM, SEM, GIXRD, UPS, SKPM, and SCLC, were conducted to investigate the properties in detail. All of the obtained experimental results confirmed the advantages of the utilization of new interfacial materials with AIE characteristics in polymer solar cells, thus providing an additional choice to develop new organic cathode interfacial layers with high performances

Biomedical applications of luminogens: General discussion

No abstract availabl

Advanced functional luminogens in the solid-state: General discussion

No abstract availabl