Predatory Grooming and Epistemology with Lauren Leydon-Hardy

Overview & Shownotes Grooming is a practice used to lure victims into an exploitative relationship. The philosopher Lauren Leydon-Hardy explores the ways that predatory grooming can interfere with the very way that a person thinks about themselves and the world. She calls this form of harm “epistemic infringement.” For the episode transcript, download a copy or read it below. Contact us at [email protected] Links to people and ideas mentioned in the show Lauren Leydon-Hardy, “Predatory Grooming and Epistemic Infringement“ Forensic research psychologist Ian Elliott Rachel Denhollander’s testimony in the trial of Larry Nassar Credits Thanks to Evelyn Brosius for our logo. Music featured in the show: “Single Still” by Blue Dot Sessions “Cran Ras” by Blue Dot Session

Depression and anxiety in prostate cancer: a systematic review and meta-analysis of prevalence rates

ObjectivesTo systematically review the literature pertaining to the prevalence of depression and anxiety in patients with prostate cancer as a function of treatment stage.DesignSystematic review and meta-analysis.Participants4494 patients with prostate cancer from primary research investigations.Primary outcome measureThe prevalence of clinical depression and anxiety in patients with prostate cancer as a function of treatment stage.ResultsWe identified 27 full journal articles that met the inclusion criteria for entry into the meta-analysis resulting in a pooled sample size of 4494 patients. The meta-analysis of prevalence rates identified pretreatment, on-treatment and post-treatment depression prevalences of 17.27% (95% CI 15.06% to 19.72%), 14.70% (95% CI 11.92% to 17.99%) and 18.44% (95% CI 15.18% to 22.22%), respectively. Pretreatment, on-treatment and post-treatment anxiety prevalences were 27.04% (95% CI 24.26% to 30.01%), 15.09% (95% CI 12.15% to 18.60%) and 18.49% (95% CI 13.81% to 24.31%), respectively.ConclusionsOur findings suggest that the prevalence of depression and anxiety in men with prostate cancer, across the treatment spectrum, is relatively high. In light of the growing emphasis placed on cancer survivorship, we consider that further research within this area is warranted to ensure that psychological distress in patients with prostate cancer is not underdiagnosed and undertreated

Suggested administrative procedures for a large private day camp

This item was digitized by the Internet Archive. Thesis (Ed.M.)--Boston Universityhttps://archive.org/details/suggestedadminis00ley

Methodology for the Establishment of Primary Porcine Vocal Fold Epithelial Cell Cultures

Objective: A current lack of methods for epithelial cell culture significantly hinders our understanding of the role of the epithelial and mucus barriers in vocal fold health and disease. Our first objective was to establish reproducible techniques for the isolation and culture of primary porcine vocal fold epithelial cells. Our second objective was to evaluate the functional significance of cell cultures using an in vitro exposure to an inflammatory cytokine. Methods: Epithelial cells were isolated from porcine vocal folds and expanded in culture. Characterization of cultures was completed by immunostaining with markers for pan-cytokeratin (epithelial cells), vimentin (stromal cells), von Willebrand factor (endothelial cell), and MUC1 and MUC4 (mucin) glycoproteins. Established epithelial cell cultures were then exposed to the inflammatory cytokine tumor necrosis factor alpha (TNF-α) for 24-hours, and transcript expression of MUC1 and MUC4 was evaluated. Results: Reproducible, porcine vocal fold epithelial cell cultures, demonstrating cobblestone appearance characteristic of the typical morphology of epithelial cell cultures were created. Cells showed positive staining for pan-cytokeratin with limited expression of vimentin and von Willebrand factor. Epithelial cells also expressed MUC1 and MUC4. TNF-α significantly increased transcript expression of MUC4. Conclusion: Here, we present the first report of successful culture of primary porcine vocal fold epithelial cells. Cultures will provide researchers with a valuable new in vitro tool to investigate vocal fold epithelium and mucus as well as the effects of common challenges, including inflammatory cytokines, on these barriers

Understanding the delayed prescribing of antibiotics for respiratory tract infection in primary care: a qualitative analysis

OBJECTIVE: To identify general practitioner (GP) views and understanding on the use of delayed prescribing in primary care.DESIGN: Qualitative semistructured telephone interview study.SETTING: Primary care general practices in England.PARTICIPANTS: 32 GPs from identified high-prescribing and low-prescribing general practices in England.METHOD: Semistructured telephone interviews were conducted with GPs identified from practices within clinical commissioning groups with the highest and lowest prescribing rates in England. A thematic analysis of the data was conducted to generate themes.RESULTS: All GPs had a good understanding of respiratory tract infection (RTI) management and how the delayed prescribing approach could be used in primary care. However, GPs highlighted factors that were influential as to whether delayed prescribing was successfully carried out during the consultation. These included the increase in evidence of antimicrobial resistance, and GPs' prior experiences of using delayed prescribing during the consultation. The patient-practitioner relationship could also influence treatment outcomes for RTI, and a lack of an agreed prescribing strategy within and between practices was considered to be of significance to GPs. Participants expressed that a lack of feedback on prescribing data at an individual and practice level made it difficult to know if delayed prescribing strategies were successful in reducing unnecessary consumption. GPs agreed that coherent and uniform training and guidelines would be of some benefit to ensure consistent prescribing throughout the UK.CONCLUSIONS: Delayed prescribing is encouraged in primary care, but is not always implemented successfully. Greater uniformity within and between practices in the UK is needed to operationalise delayed prescribing, as well as providing feedback on the uptake of antibiotics. Finally, GPs may need further guidance on how to answer the concerns of patients without interpreting these questions as a demand for antibiotics, as well as educating the patient about antimicrobial resistance and supporting a good patient-practitioner relationship

Communication in UK outpatient oncology consultations

This thesis is based on a sociological analysis of outpatient oncology consultations involving doctors and patients. Most patients have had surgery to remove their cancer. All have been referred for radiotherapy or chemotherapy and have been told on previous occasions that they have cancer. I demonstrate how information about cancer is managed between doctors and patients. Analysis draws on some of the insights and principles of applied conversation analytic work. I report on a range of short and long transcribed data fragments, drawn from a tape-recorded data corpus. Whilst respecting the "autonomy" of the recorded data, I occasionally and informally draw on observations made during fieldwork to crystallize analytic claims. Analytic foci are derived from the natural unfolding of the consultation trajectory. Three key topics are addressed: how doctors use history-taking to establish patient journeys to ascertain what patients know of their cancer; how diagnoses are embellished and treatment implications discussed; and how, within diagnostic and treatment talk, the participants negotiate the good, the bad and the uncertain character of the information shared. I revisit the broad (and predominant) policy and research literature to confirm the benefits of conversation analytic work and the particular insights provided by this thesis. I also delineate some of the broader themes to emanate from the detailed analysis and challenge some common conceptualisations of "doctor-patient communication". Finally, I close with a discussion of the limitations of this thesis and possibilities for further work