1,662 research outputs found
Discrete quark-lepton symmetry need not pose a cosmological domain wall problem
Quarks and leptons may be related to each other through a spontaneously
broken discrete symmetry. Models with acceptable and interesting collider
phenomenology have been constructed which incorporate this idea. However, the
standard Hot Big Bang model of cosmology is generally considered to eschew
spontaneously broken discrete symmetries because they often lead to the
formation of unacceptably massive domain walls. We point out that there are a
number of plausible quark-lepton symmetric models which do not produce
cosmologically troublesome domain walls. We also raise what we think are some
interesting questions concerning anomalous discrete symmetries.Comment: 35pp, LATEX, PURD-TH-92-1
Hemispherical power asymmetry: parameter estimation from CMB WMAP5 data
We reexamine the evidence of the hemispherical power asymmetry, detected in
the CMB WMAP data using a new method. At first, we analyze the hemispherical
variance ratios and compare these with simulated distributions. Secondly,
working within a previously-proposed CMB bipolar modulation model, we constrain
model parameters: the amplitude and the orientation of the modulation field as
a function of various multipole bins. Finally, we select three ranges of
multipoles leading to the most anomalous signals, and we process corresponding
100 Gaussian, random field (GRF) simulations, treated as observational data, to
further test the statistical significance and robustness of the hemispherical
power asymmetry. For our analysis we use the Internally-Linearly-Coadded (ILC)
full sky map, and KQ75 cut-sky V channel, foregrounds reduced map of the WMAP
five year data (V5). We constrain the modulation parameters using a generic
maximum a posteriori method.
In particular, we find differences in hemispherical power distribution, which
when described in terms of a model with bipolar modulation field, exclude the
field amplitude value of the isotropic model A=0 at confidence level of ~99.5%
(~99.4%) in the multipole range l=[7,19] (l=[7,79]) in the V5 data, and at the
confidence level ~99.9% in the multipole range l=[7,39] in the ILC5 data, with
the best fit (modal PDF) values in these particular multipole ranges of A=0.21
(A=0.21) and A=0.15 respectively. However, we also point out that similar or
larger significances (in terms of rejecting the isotropic model), and large
best-fit modulation amplitudes are obtained in GRF simulations as well, which
reduces the overall significance of the CMB power asymmetry down to only about
94% (95%) in the V5 data, in the range l=[7,19] (l=[7,79]).Comment: 24 pages, 10 figures; few typos corrected; published in JCA
Electric Charge Quantization
Experimentally it has been known for a long time that the electric charges of
the observed particles appear to be quantized. An approach to understanding
electric charge quantization that can be used for gauge theories with explicit
factors -- such as the standard model and its variants -- is
pedagogically reviewed and discussed in this article. This approach uses the
allowed invariances of the Lagrangian and their associated anomaly cancellation
equations. We demonstrate that charge may be de-quantized in the
three-generation standard model with massless neutrinos, because differences in
family-lepton--numbers are anomaly-free. We also review the relevant
experimental limits. Our approach to charge quantization suggests that the
minimal standard model should be extended so that family-lepton--number
differences are explicitly broken. We briefly discuss some candidate extensions
(e.g. the minimal standard model augmented by Majorana right-handed neutrinos).Comment: 18 pages, LaTeX, UM-P-92/5
From START to FINISH : the influence of osmotic stress on the cell cycle
Peer reviewedPublisher PD
Spin relaxation in (110) and (001) InAs/GaSb superlattices
We report an enhancement of the electron spin relaxation time (T1) in a (110)
InAs/GaSb superlattice by more than an order of magnitude (25 times) relative
to the corresponding (001) structure. The spin dynamics were measured using
polarization sensitive pump probe techniques and a mid-infrared, subpicosecond
PPLN OPO. Longer T1 times in (110) superlattices are attributed to the
suppression of the native interface asymmetry and bulk inversion asymmetry
contributions to the precessional D'yakonov Perel spin relaxation process.
Calculations using a nonperturbative 14-band nanostructure model give good
agreement with experiment and indicate that possible structural inversion
asymmetry contributions to T1 associated with compositional mixing at the
superlattice interfaces may limit the observed spin lifetime in (110)
superlattices. Our findings have implications for potential spintronics
applications using InAs/GaSb heterostructures.Comment: 4 pages, 2 figure
Searching for planar signatures in WMAP
We search for planar deviations of statistical isotropy in the Wilkinson
Microwave Anisotropy Probe (WMAP) data by applying a recently introduced
angular-planar statistics both to full-sky and to masked temperature maps,
including in our analysis the effect of the residual foreground contamination
and systematics in the foreground removing process as sources of error. We
confirm earlier findings that full-sky maps exhibit anomalies at the planar
() and angular () scales and , which
seem to be due to unremoved foregrounds since this features are present in the
full-sky map but not in the masked maps. On the other hand, our test detects
slightly anomalous results at the scales and in the
masked maps but not in the full-sky one, indicating that the foreground
cleaning procedure (used to generate the full-sky map) could not only be
creating false anomalies but also hiding existing ones. We also find a
significant trace of an anomaly in the full-sky map at the scale
, which is still present when we consider galactic cuts of
18.3% and 28.4%. As regards the quadrupole (), we find a coherent
over-modulation over the whole celestial sphere, for all full-sky and cut-sky
maps. Overall, our results seem to indicate that current CMB maps derived from
WMAP data do not show significant signs of anisotropies, as measured by our
angular-planar estimator. However, we have detected a curious coherence of
planar modulations at angular scales of the order of the galaxy's plane, which
may be an indication of residual contaminations in the full- and cut-sky maps.Comment: 15 pages with pdf figure
Consequences of local gauge symmetry in empirical tight-binding theory
A method for incorporating electromagnetic fields into empirical
tight-binding theory is derived from the principle of local gauge symmetry.
Gauge invariance is shown to be incompatible with empirical tight-binding
theory unless a representation exists in which the coordinate operator is
diagonal. The present approach takes this basis as fundamental and uses group
theory to construct symmetrized linear combinations of discrete coordinate
eigenkets. This produces orthogonal atomic-like "orbitals" that may be used as
a tight-binding basis. The coordinate matrix in the latter basis includes
intra-atomic matrix elements between different orbitals on the same atom.
Lattice gauge theory is then used to define discrete electromagnetic fields and
their interaction with electrons. Local gauge symmetry is shown to impose
strong restrictions limiting the range of the Hamiltonian in the coordinate
basis. The theory is applied to the semiconductors Ge and Si, for which it is
shown that a basis of 15 orbitals per atom provides a satisfactory description
of the valence bands and the lowest conduction bands. Calculations of the
dielectric function demonstrate that this model yields an accurate joint
density of states, but underestimates the oscillator strength by about 20% in
comparison to a nonlocal empirical pseudopotential calculation.Comment: 23 pages, 7 figures, RevTeX4; submitted to Phys. Rev.
A Characterization of Scale Invariant Responses in Enzymatic Networks
An ubiquitous property of biological sensory systems is adaptation: a step
increase in stimulus triggers an initial change in a biochemical or
physiological response, followed by a more gradual relaxation toward a basal,
pre-stimulus level. Adaptation helps maintain essential variables within
acceptable bounds and allows organisms to readjust themselves to an optimum and
non-saturating sensitivity range when faced with a prolonged change in their
environment. Recently, it was shown theoretically and experimentally that many
adapting systems, both at the organism and single-cell level, enjoy a
remarkable additional feature: scale invariance, meaning that the initial,
transient behavior remains (approximately) the same even when the background
signal level is scaled. In this work, we set out to investigate under what
conditions a broadly used model of biochemical enzymatic networks will exhibit
scale-invariant behavior. An exhaustive computational study led us to discover
a new property of surprising simplicity and generality, uniform linearizations
with fast output (ULFO), whose validity we show is both necessary and
sufficient for scale invariance of enzymatic networks. Based on this study, we
go on to develop a mathematical explanation of how ULFO results in scale
invariance. Our work provides a surprisingly consistent, simple, and general
framework for understanding this phenomenon, and results in concrete
experimental predictions
The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms
© 2008 by The American Society for Cell Biology. Under the License and Publishing Agreement, authors grant to the general public, effective two months after publication of (i.e.,. the appearance of) the edited manuscript in an online issue of MBoC, the nonexclusive right to copy, distribute, or display the manuscript subject to the terms of the Creative Commons–Noncommercial–Share Alike 3.0 Unported license (http://creativecommons.org/licenses/by-nc-sa/3.0).The small guanosine triphosphate (GTP)-binding proteins of the Rho family are implicated in various cell functions, including establishment and maintenance of cell polarity. Activity of Rho guanosine triphosphatases (GTPases) is not only regulated by guanine nucleotide exchange factors and GTPase-activating proteins but also by guanine nucleotide dissociation inhibitors (GDIs). These proteins have the ability to extract Rho proteins from membranes and keep them in an inactive cytosolic complex. Here, we show that Rdi1, the sole Rho GDI of the yeast Saccharomyces cerevisiae, contributes to pseudohyphal growth and mitotic exit. Rdi1 interacts only with Cdc42, Rho1, and Rho4, and it regulates these Rho GTPases by distinct mechanisms. Binding between Rdi1 and Cdc42 as well as Rho1 is modulated by the Cdc42 effector and p21-activated kinase Cla4. After membrane extraction mediated by Rdi1, Rho4 is degraded by a novel mechanism, which includes the glycogen synthase kinase 3β homologue Ygk3, vacuolar proteases, and the proteasome. Together, these results indicate that Rdi1 uses distinct modes of regulation for different Rho GTPases.Deutsche Forschungsgemeinschaf
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