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    Upstairs downstairs: how introducing computer technology changed skills and pay on two floors of Cabot Bank

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    Assessing the differing impacts of a new computer technology on skills and pay in two departments of a large bank.Checks ; Check collection systems ; Check float ; Job security ; Employees, Training of

    A RESTful API for exchanging Materials Data in the AFLOWLIB.org consortium

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    The continued advancement of science depends on shared and reproducible data. In the field of computational materials science and rational materials design this entails the construction of large open databases of materials properties. To this end, an Application Program Interface (API) following REST principles is introduced for the AFLOWLIB.org materials data repositories consortium. AUIDs (Aflowlib Unique IDentifier) and AURLs (Aflowlib Uniform Resource locator) are assigned to the database resources according to a well-defined protocol described herein, which enables the client to access, through appropriate queries, the desired data for post-processing. This introduces a new level of openness into the AFLOWLIB repository, allowing the community to construct high-level work-flows and tools exploiting its rich data set of calculated structural, thermodynamic, and electronic properties. Furthermore, federating these tools would open the door to collaborative investigation of the data by an unprecedented extended community of users to accelerate the advancement of computational materials design and development.Comment: 22 pages, 7 figure

    Upstairs, Downstairs: Computer-Skill Complementarity and Computer-Labor Substitution on Two Floors of a Large Bank

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    We describe how a single technological innovation, the introduction of image processing of checks, led to distinctly different changes in the structure of jobs in two departments of a large bank overseen by one group of managers. In the downstairs deposit processing department, image processing led to the substitution of computers for high school educated labor in accomplishing core tasks and in greater specialization in the jobs that remained. In the upstairs exceptions processing department, image processing led to the integration of tasks, with an associated increase in the demand for particular skills. The case illustrates the interdependence of technological change and organizational change. It suggests that seeing the whole picture' and associated conceptual and problem-solving skills are made more valuable by information technologies. Finally, it underscores that the short-term consequences of technological changes may depend importantly on regulatory forces.

    AFLOW-SYM: Platform for the complete, automatic and self-consistent symmetry analysis of crystals

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    Determination of the symmetry profile of structures is a persistent challenge in materials science. Results often vary amongst standard packages, hindering autonomous materials development by requiring continuous user attention and educated guesses. Here, we present a robust procedure for evaluating the complete suite of symmetry properties, featuring various representations for the point-, factor-, space groups, site symmetries, and Wyckoff positions. The protocol determines a system-specific mapping tolerance that yields symmetry operations entirely commensurate with fundamental crystallographic principles. The self consistent tolerance characterizes the effective spatial resolution of the reported atomic positions. The approach is compared with the most used programs and is successfully validated against the space group information provided for over 54,000 entries in the Inorganic Crystal Structure Database. Subsequently, a complete symmetry analysis is applied to all 1.7++ million entries of the AFLOW data repository. The AFLOW-SYM package has been implemented in, and made available for, public use through the automated, ab-initio\textit{ab-initio} framework AFLOW.Comment: 24 pages, 6 figure

    Images of Energy

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    Six members of the Syracuse community discuss energy as it is understood in the fields of psychology, graphic arts, biology, architecture, physics, and literature. Professor Weissman provides an overview

    Impairment of Methotrexate Transport Is Common in Osteosarcoma Tumor Samples

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    Osteosarcoma does not respond well to conventional dose methotrexate but does respond to high-dose methotrexate. Previous work has indicated that this resistance may be due to impaired transport of methotrexate across the cell membrane. In this study, the PT430 competitive displacement assay was adapted to evaluate methotrexate transport in 69 high-grade osteosarcoma tumor samples. All samples studied were shown to have relatively impaired methotrexate transport by PT430 assay. Ninety-nine percent of the samples had less than 20% PT430 displacement by methotrexate. Eighty-eight percent exhibited displacement by methotrexate at less than 50% of the displacement by trimetrexate. The high frequency of impaired transport suggests the presence of decreased functionality of the reduced folate carrier protein. The overwhelming presence of impaired transport may explain why methotrexate needs to be given in high doses to be effective in osteosarcoma therapy and suggests that reduced folate carrier-independent antifolates should be explored

    Black carbon as an additional indicator of the adverse health effects of airborne particles compared with PM10 and PM2.5.

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    Current air quality standards for particulate matter (PM) use the PM mass concentration [PM with aerodynamic diameters ≤ 10 μm (PM(10)) or ≤ 2.5 μm (PM(2.5))] as a metric. It has been suggested that particles from combustion sources are more relevant to human health than are particles from other sources, but the impact of policies directed at reducing PM from combustion processes is usually relatively small when effects are estimated for a reduction in the total mass concentration

    Quantum Clock Synchronization Based on Shared Prior Entanglement

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    We demonstrate that two spatially separated parties (Alice and Bob) can utilize shared prior quantum entanglement, and classical communications, to establish a synchronized pair of atomic clocks. In contrast to classical synchronization schemes, the accuracy of our protocol is independent of Alice or Bob's knowledge of their relative locations or of the properties of the intervening medium.Comment: 4 page
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