(Not) Higher, Stronger or Swifter: Representation of Female Olympic Athletes in the Israeli Press

Despite the IOC declaration of intent for gender equality in sport and in light of the fact that a greater number of women are participating in the Olympic Games covert connotations are hidden behind the distorted and biased image presented of female athletes in the press. The current study asks whether the size and extent of coverage really matter; does more extensive coverage necessarily mean equal and true representation of women in sport, or are we getting more of the same? The findings in this study indicate two parallel processes in terms of article content: First, the greater the number of articles, the more stereotypical and biased the content becomes. Secondly, over the years, representation of female athletes has become increasingly negative and biased. Over the three Olympic Games examined (1996, 2000, 2004), female athletes were presented in a biased and stereotypical ways in relative to male athletes. The change in coverage over the years has proven to be a tendency to stereotypically present female athletes in a more negative light in comparison to male athletes

Treatment‐free remission after dasatinib in patients with chronic myeloid leukaemia in chronic phase with deep molecular response: Final 5‐year analysis of DASFREE

Patients with chronic myeloid leukaemia in chronic phase (CML-CP) who have a sustained deep molecular response (DMR) are eligible to discontinue treatment and attempt treatment-free remission (TFR). In the DASFREE study (ClinicalTrials.gov; NCT01850004), the 2-year TFR rate after dasatinib discontinuation was 46%; here we present the 5-year update. Patients with a stable DMR after ≥2 years of dasatinib therapy discontinued treatment and were followed for 5 years. At a minimum follow-up of 60 months, in 84 patients discontinuing dasatinib, the 5-year TFR rate was 44% (n = 37). No relapses occurred after month 39 and all evaluable patients who relapsed and restarted dasatinib (n = 46) regained a major molecular response in a median of 1.9 months. The most common adverse event during the off-treatment period was arthralgia (18%, 15/84); a total of 15 withdrawal events were reported in nine patients (11%). At the 5-year final follow-up, almost half of the patients who discontinued dasatinib after a sustained DMR maintained TFR. All evaluable patients who experienced a relapse quickly regained a DMR after restarting dasatinib, demonstrating that dasatinib discontinuation is a viable and potentially long-term option in patients with CML-CP. The safety profile is consistent with the previous report

Israeli football as an arena for post-colonial struggle: The case of Beitar Jerusalem FC

The current study endeavors to place the case of Beitar Jerusalem FC and its fans, as depicted in media, entertainment and public discourse in Israel, within an Orient-Occident theoretical framework. For this purpose the study adopts an acknowledged theoretical framework of the relationship between East and West, which examines the relations between these two political and geographic cultural poles as a power struggle between those who are perceived as the conquerors (colonialists) and the conquered (natives). This theoretical framework, known as ‘post-colonial discourse’, deals with salient characteristics of power relations in a global society following the colonial period of the major European powers

Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation

Cryoablation of a solitary tumor mass releases intact tumor antigens and can induce protective antitumor immunity but has limited efficacy in the treatment of established metastatic cancer. Cyclophosphamide (Cy), an anticancer drug, selectively depletes regulatory T cells (Tregs) and attenuates suppression of antitumor immunity. We used a BALB/c mouse model of metastatic colon cancer to investigate the systemic antitumor effects of in situ cryotherapy alone or in combination with 200 mg/kg i.p. Cy. When combined with Cy, cryoablation was significantly more effective than either surgical excision or cautery at inducing systemic antitumor immunity, resulting in the cure of a fraction of animals with established metastatic disease and resistance to tumor rechallenge. Lymphocytes from cured animals contained an expanded population of tumor-specific, interferon-γ producing T cells and transferred antitumor immunity to naive recipients. Depletion of CD8+ cells significantly impaired the adoptive transfer of antitumor immunity. Furthermore, treatment with Cy and cryoablation was associated with a significant decrease in the ratio of regulatory to effector CD4+ T cells. The combination of tumor cryoablation and Cy induces potent, systemic antitumor immunity in animals with established metastatic disease