Dovetail: Stronger Anonymity in Next-Generation Internet Routing

Current low-latency anonymity systems use complex overlay networks to conceal a user's IP address, introducing significant latency and network efficiency penalties compared to normal Internet usage. Rather than obfuscating network identity through higher level protocols, we propose a more direct solution: a routing protocol that allows communication without exposing network identity, providing a strong foundation for Internet privacy, while allowing identity to be defined in those higher level protocols where it adds value. Given current research initiatives advocating "clean slate" Internet designs, an opportunity exists to design an internetwork layer routing protocol that decouples identity from network location and thereby simplifies the anonymity problem. Recently, Hsiao et al. proposed such a protocol (LAP), but it does not protect the user against a local eavesdropper or an untrusted ISP, which will not be acceptable for many users. Thus, we propose Dovetail, a next-generation Internet routing protocol that provides anonymity against an active attacker located at any single point within the network, including the user's ISP. A major design challenge is to provide this protection without including an application-layer proxy in data transmission. We address this challenge in path construction by using a matchmaker node (an end host) to overlap two path segments at a dovetail node (a router). The dovetail then trims away part of the path so that data transmission bypasses the matchmaker. Additional design features include the choice of many different paths through the network and the joining of path segments without requiring a trusted third party. We develop a systematic mechanism to measure the topological anonymity of our designs, and we demonstrate the privacy and efficiency of our proposal by simulation, using a model of the complete Internet at the AS-level

Relative duration of pulmonary venous and mitral a waves: a measure of LV compliance or LVEDP? mathematical analysis

Fuente Fuente, Carlos;Julián García, Eva María;Vintró, Jose

Ab initio density functional investigation of B_24 cluster: Rings, Tubes, Planes, and Cages

We investigate the equilibrium geometries and the systematics of bonding in various isomers of a 24-atom boron cluster using Born-Oppenheimer molecular dynamics within the framework of density functional theory. The isomers studied are the rings, the convex and the quasiplanar structures, the tubes and, the closed structures. A staggered double-ring is found to be the most stable structure amongst the isomers studied. Our calculations reveal that a 24-atom boron cluster does form closed 3-d structures. All isomers show staggered arrangement of nearest neighbor atoms. Such a staggering facilitates $sp^2$ hybridization in boron cluster. A polarization of bonds between the peripheral atoms in the ring and the planar isomers is also seen. Finally, we discuss the fusion of two boron icosahedra. We find that the fusion occurs when the distance between the two icosahedra is less than a critical distance of about 6.5a.u.Comment: 8 pages, 9 figures in jpeg format Editorially approved for publication in Phys. Rev.

Motion-Compensation Techniques in Neonatal and Fetal MR Imaging

Fetal and neonatal MR imaging is increasingly used as a complementary diagnostic tool to sonography. MR imaging is an ideal technique for imaging fetuses and neonates because of the absence of ionizing radiation, the superior contrast of soft tissues compared with sonography, the availability of different contrast options, and the increased FOV. Motion in the normally mobile fetus and the unsettled, sleeping, or sedated neonate during a long acquisition will decrease image quality in the form of motion artifacts, hamper image interpretation, and often necessitate a repeat MR imaging to establish a diagnosis. This article reviews current techniques of motion compensation in fetal and neonatal MR imaging, including the following: 1) motion-prevention strategies (such as adequate patient preparation, patient coaching, and sedation, when required), 2) motion-artifacts minimization methods (such as fast imaging protocols, data undersampling, and motion-resistant sequences), and 3) motion-detection/correction schemes (such as navigators and self-navigated sequences, external motion-tracking devices, and postprocessing approaches) and their application in fetal and neonatal brain MR imaging. Additionally some background on the repertoire of motion of the fetal and neonatal patient and the resulting artifacts will be presented, as well as insights into future developments and emerging techniques of motion compensation

Safety and Efficacy of Dronedarone in the Treatment of Atrial Fibrillation/Flutter

Dronedarone is an amiodarone analog but differs structurally from amiodarone in that the iodine moiety was removed and a methane-sulfonyl group was added. These modifications reduced thyroid and other end-organ adverse effects and makes dronedarone less lipophilic, shortening its half-life. Dronedarone has been shown to prevent atrial fibrillation/flutter (AF/AFl) recurrences in several multi-center trials. In addition to its rhythm control properties, dronedarone has rate control properties and slows the ventricular response during AF. Dronedarone is approved in Europe for rhythm and rate control indications. In patients with decompensated heart failure, dronedarone treatment increased mortality and cardiovascular hospitalizations. However, when dronedarone was used in elderly high risk AF/AFl patients excluding such high risk heart failure, cardiovascular hospitalizations were significantly reduced and the drug was approved in the USA for this indication in 2009 by the Food and Drug Administration. Updated guidelines suggest dronedarone as a front-line antiarrhythmic in many patients with AF/Fl but caution that the drug should not be used in patients with advanced heart failure. In addition, the recent results of the PALLAS trial suggest that dronedarone should not be used in the long-term treatment of patients with permanent AF

Self-similarity and novel sample-length-dependence of conductance in quasiperiodic lateral magnetic superlattices

We study the transport of electrons in a Fibonacci magnetic superlattice produced on a two-dimensional electron gas modulated by parallel magnetic field stripes arranged in a Fibonacci sequence. Both the transmission coefficient and conductance exhibit self-similarity and the six-circle property. The presence of extended states yields a finite conductivity at infinite length, that may be detected as an abrupt change in the conductance as the Fermi energy is varied, much as a metal-insulator transition. This is a unique feature of transport in this new kind of structure, arising from its inherent two-dimensional nature.Comment: 9 pages, 5 figures, revtex, important revisions made. to be published in Phys. Rev.

Variational Approximations in a Path-Integral Description of Potential Scattering

Using a recent path integral representation for the T-matrix in nonrelativistic potential scattering we investigate new variational approximations in this framework. By means of the Feynman-Jensen variational principle and the most general ansatz quadratic in the velocity variables -- over which one has to integrate functionally -- we obtain variational equations which contain classical elements (trajectories) as well as quantum-mechanical ones (wave spreading).We analyse these equations and solve them numerically by iteration, a procedure best suited at high energy. The first correction to the variational result arising from a cumulant expansion is also evaluated. Comparison is made with exact partial-wave results for scattering from a Gaussian potential and better agreement is found at large scattering angles where the standard eikonal-type approximations fail.Comment: 35 pages, 3 figures, 6 tables, Latex with amsmath, amssymb; v2: 28 pages, EPJ style, misprints corrected, note added about correct treatment of complex Gaussian integrals with the theory of "pencils", matches published versio

Lubricating Bacteria Model for Branching growth of Bacterial Colonies

Various bacterial strains (e.g. strains belonging to the genera Bacillus, Paenibacillus, Serratia and Salmonella) exhibit colonial branching patterns during growth on poor semi-solid substrates. These patterns reflect the bacterial cooperative self-organization. Central part of the cooperation is the collective formation of lubricant on top of the agar which enables the bacteria to swim. Hence it provides the colony means to advance towards the food. One method of modeling the colonial development is via coupled reaction-diffusion equations which describe the time evolution of the bacterial density and the concentrations of the relevant chemical fields. This idea has been pursued by a number of groups. Here we present an additional model which specifically includes an evolution equation for the lubricant excreted by the bacteria. We show that when the diffusion of the fluid is governed by nonlinear diffusion coefficient branching patterns evolves. We study the effect of the rates of emission and decomposition of the lubricant fluid on the observed patterns. The results are compared with experimental observations. We also include fields of chemotactic agents and food chemotaxis and conclude that these features are needed in order to explain the observations.Comment: 1 latex file, 16 jpeg files, submitted to Phys. Rev.

Twenty five years after KLS: A celebration of non-equilibrium statistical mechanics

When Lenz proposed a simple model for phase transitions in magnetism, he couldn't have imagined that the "Ising model" was to become a jewel in field of equilibrium statistical mechanics. Its role spans the spectrum, from a good pedagogical example to a universality class in critical phenomena. A quarter century ago, Katz, Lebowitz and Spohn found a similar treasure. By introducing a seemingly trivial modification to the Ising lattice gas, they took it into the vast realms of non-equilibrium statistical mechanics. An abundant variety of unexpected behavior emerged and caught many of us by surprise. We present a brief review of some of the new insights garnered and some of the outstanding puzzles, as well as speculate on the model's role in the future of non-equilibrium statistical physics.Comment: 3 figures. Proceedings of 100th Statistical Mechanics Meeting, Rutgers, NJ (December, 2008