A Two-Spirit Journey: The Autobiography of a Lesbian Ojibwa-Cree Elder by Ma-Nee Chacaby with Mary Louisa Plummer

Review of A Two-Spirit Journey: The Autobiography of a Lesbian Ojibwa-Cree Elder by Ma-Nee Chacaby with Mary Louisa Plummer

Acoustic transducer apparatus with reduced thermal conduction

A horn is described for transmitting sound from a transducer to a heated chamber containing an object which is levitated by acoustic energy while it is heated to a molten state, which minimizes heat transfer to thereby minimize heating of the transducer, minimize temperature variation in the chamber, and minimize loss of heat from the chamber. The forward portion of the horn, which is the portion closest to the chamber, has holes that reduce its cross-sectional area to minimize the conduction of heat along the length of the horn, with the entire front portion of the horn being rigid and having an even front face to efficiently transfer high frequency acoustic energy to fluid in the chamber. In one arrangement, the horn has numerous rows of holes extending perpendicular to the length of horn, with alternate rows extending perpendicular to one another to form a sinuous path for the conduction of heat along the length of the horn

A Two-Spirit Journey: The Autobiography of a Lesbian Ojibwa-Cree Elder by Ma-Nee Chacaby with Mary Louisa Plummer

Review of A Two-Spirit Journey: The Autobiography of a Lesbian Ojibwa-Cree Elder by Ma-Nee Chacaby with Mary Louisa Plummer

Plasma heating for containerless and microgravity materials processing

A method for plasma heating of levitated samples to be used in containerless microgravity processing is disclosed. A sample is levitated by electrostatic, electromagnetic, aerodynamic, or acoustic systems, as is appropriate for the physical properties of the particular sample. The sample is heated by a plasma torch at atmospheric pressure. A ground plate is provided to help direct the plasma towards the sample. In addition, Helmholtz coils are provided to produce a magnetic field that can be used to spiral the plasma around the sample. The plasma heating system is oriented such that it does not interfere with the levitation system

Cerebral atrophy in mild cognitive impairment and Alzheimer disease: rates and acceleration.

OBJECTIVE: To quantify the regional and global cerebral atrophy rates and assess acceleration rates in healthy controls, subjects with mild cognitive impairment (MCI), and subjects with mild Alzheimer disease (AD). METHODS: Using 0-, 6-, 12-, 18-, 24-, and 36-month MRI scans of controls and subjects with MCI and AD from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, we calculated volume change of whole brain, hippocampus, and ventricles between all pairs of scans using the boundary shift integral. RESULTS: We found no evidence of acceleration in whole-brain atrophy rates in any group. There was evidence that hippocampal atrophy rates in MCI subjects accelerate by 0.22%/year2 on average (p = 0.037). There was evidence of acceleration in rates of ventricular enlargement in subjects with MCI (p = 0.001) and AD (p < 0.001), with rates estimated to increase by 0.27 mL/year2 (95% confidence interval 0.12, 0.43) and 0.88 mL/year2 (95% confidence interval 0.47, 1.29), respectively. A post hoc analysis suggested that the acceleration of hippocampal loss in MCI subjects was mainly driven by the MCI subjects that were observed to progress to clinical AD within 3 years of baseline, with this group showing hippocampal atrophy rate acceleration of 0.50%/year2 (p = 0.003). CONCLUSIONS: The small acceleration rates suggest a long period of transition to the pathologic losses seen in clinical AD. The acceleration in hippocampal atrophy rates in MCI subjects in the ADNI seems to be driven by those MCI subjects who concurrently progressed to a clinical diagnosis of AD

exo-FISH: protocol for detecting DNA breaks in repetitive regions of mammalian genomes

Detecting DNA breaks in defined regions of the genome is critical to advancing our understanding of genome stability maintenance. Here, we present exo-FISH, a protocol to label exposed single-stranded DNA in defined repetitive regions of mammalian genomes by combining in vitro restriction enzyme digestion on fixed cells with fluorescence in situ hybridization (FISH). We describe steps for cell harvesting and fixation, slide treatments, and FISH probe hybridization. We then detail procedures for imaging and analysis. For complete details on the use and execution of this protocol, please refer to Saayman et al. (2023)

Modification of an Implant Material

Titanium metal is a commonly used implant material which can be colonized by bacteria. Biofilms are formed when bacteria colonizes, attaches to a surface, and immobilizes. Bacterial infections or biofilms are hard to treat once formed on the surface of a metal implant. Coating the material may minimize bacteria attachment. Self-assembled monolayers are comprised of molecules that contain both a head and tail group, and can be used to coat metal to prevent biofilm formation and bacteria growth. 12-mercaptododecylphosphonic acid self-assembled monolayers have a phosphonic acid head group and a thiol tail group. A solution of 12-mercaptododecylphosphonic acid in tetrahydrofuran was used to form self-assembled monolayers on the surface of titanium. Diffuse reflectance infrared Fourier transform spectroscopy was used to evaluate the attachment of the self-assembled monolayers. Alkyl-chain ordered self-assembled monolayers formed on the titanium surface, with the thiol tail group free at the interface for additional reactions. The monolayer attachment strength was further tested through acid, base, and tape tests

Fostering equitable access to higher education in Hong Kong : a study of the tertiary financial assistance scheme

published_or_final_versionPolitics and Public AdministrationMasterMaster of Public Administratio