Formation a valeological culture of students

Описана структура валеологической культуры молодежи. Представлено социологическое осмысление различных типов поведения молодежи в сфере здоровья. Дан анализ результатов исследования возможностей поддержания личных ресурсов и сохранения здоровья студенческой молодежью.Describe the structure of valeological culture of the youth. Presented sociological understanding of different types of behaviour of young people in the field of health. Presented an analysis of the results of investigation of possibilities to maintain personal resources and preservation of health of the student youth

INQUINAMENTO INDOOR DA RADON. UNA APPLICAZIONE DELLE RETI BAYESIANE A SUPPORTO DELLA DIAGNOSI

Nel quadro più generale della tematica del controllo della qualità ambientale e più in particolare dell’Indoor Air Quality, la presente relazione riporta lo studio di un fenomeno di inquinamento da radon riguardante la scuola “G. Mancino” di Palermo. Lo spunto viene offerto dal fatto che nel 2005, nel corso di un monitoraggio della radioattività ambientale di Palermo, i tecnici dell’ARPA Sicilia hanno rilevato in questa scuola elementare degli anni ’30, livelli di radon indoor molto superiori ai limiti di legge fissati dal D.Lgs. 241/2000. Nella prima fase, dopo lo studio delle caratteristiche tipologiche e costruttive del plesso e l’acquisizione dei dati di misura pregressi, si è proceduto ad una nuova campagna di monitoraggio rivolta al rilievo di dati e misure sperimentali sulla presenza del radon indoor e dei dati meteoclimatici del contesto specifico. Nella seconda fase è stata formulata una proposta di intervento sostenuta dall’analisi dei meccanismi di inquinamento attraverso modelli di simulazione. In particolare l’approccio metodologico dello studio procede attraverso lo sviluppo di un modello di analisi basato sulle reti bayesiane, rilevatosi uno strumento utile di supporto per la diagnosi e le conseguenti decisioni progettuali, capace di controllare e descrivere fenomeni complessi e di stimare relazioni probabilistiche tra cause ed effetti

Toxoplasma gondii Oocyst–specific Antibodies and Source of Infection

Infection source can determine cost-effective public health interventions. To quantify risk of acquiring Toxoplasma gondii from environmental sources versus from meat, we examined serum from pregnant women in Chile. Because 43% had oocyst-specific antibodies, we conclude that contaminated meat remains the primary source of infection but that environmental sources also pose substantial risk

Self-preservation behavior as a component of demographic municipal policy

В статье дается определение молодежи как социальной общности, раскрывается вопрос о важности решения социальных и демографических проблем молодежи и о необходимости изменения социальной политики в отношении данной социально незащищенной категории населения. Показано, что существует несколько этапов влияния на потребность молодежи в самосохранительном поведении. Определена значимость самосохранительного поведения в демографической и муниципальной политике.This paper provides a definition of youth as a social community, revealed the importance of resolving social and demographic problems of youth and the need for changes in social policy in relation to this, socially vulnerable categories of society. It is shown that there are several stages of influence on young people and the need. The importance of self-preservation behavior in population and municipal politics

Practical observations - the COVID-19 influence on Latvian early intervention work with first episode psychosis (FEP) patients

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Formation of Personal Competitiveness of the Student in the Educational Space of the University

Рассмотрены особенности формирования конкурентоспособности студентов — будущих чиновников. Выделены проблемные поля в процессе конкурентоориентирования студенческой молодежи. Сформулирован ряд рекомендаций, направленных на совершенствование формирования конкурентоспособности студентов в образовательном пространстве университета.The article describes the features of the formation of the competitiveness of students - future officials. The problem fields in the process of competitive orientation of students are identified. We formulated a number of recommendations aimed at improving the formation of students’ ompetitiveness in the educational space of the university

Education of Adults as a Subject of Sociological Analysis

The article analyzes the results of sociological research of attitudes of adults to receive additional education; the problem field in the organization of the educational process is revealed. We have formulated conclusions that determine the possible directions of improvement of the organization of professional education of adults. It is proposed to consistently use the basic principles and procedures of the technological approach to eliminate problem areas in the process of organizing additional professional education.В статье проанализированы результаты социологического исследования установок взрослых на получение дополнительного образования; выявлено проблемное поле в организации образовательного процесса. Сформулированы выводы, определяющие возможные направления совершенствования организации профессионального образования взрослых. Предлагается последовательное использование основных принципов и процедур технологического подхода для устранения проблемных зон в процессе организации дополнительного профессионального образования.The article is prepared with the support of Russian Foundation for Basic Research, project № 19-011-00096 «Education as a resource for the preservation and development of the «third age» people».Исследование выполнено при финансовой поддержке РФФИ в рамках научного проекта № 19-011-00096 «Образование как ресурс сохранения и развития социальной общности людей "третьего возраста"»

Finite difference analysis and experimental validation of 3D photonic crystals for structural health monitoring

Copyright 2017 Society of Photo‑Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited

Exploiting inflammation for therapeutic gain in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy associated with <5% 5-year survival, in which standard chemotherapeutics have limited benefit. The disease is associated with significant intra- and peritumoral inflammation and failure of protective immunosurveillance. Indeed, inflammatory signals are implicated in both tumour initiation and tumour progression. The major pathways regulating PDAC-associated inflammation are now being explored. Activation of leukocytes, and upregulation of cytokine and chemokine signalling pathways, both have been shown to modulate PDAC progression. Therefore, targeting inflammatory pathways may be of benefit as part of a multi-target approach to PDAC therapy. This review explores the pathways known to modulate inflammation at different stages of tumour development, drawing conclusions on their potential as therapeutic targets in PDAC

Aerosolized BC-819 Inhibits Primary but Not Secondary Lung Cancer Growth

Despite numerous efforts, drug based treatments for patients suffering from lung cancer remains poor. As a promising alternative, we investigated the therapeutic potential of BC-819 for the treatment of lung cancer in mouse tumor models. BC-819 is a novel plasmid DNA which encodes for the A-fragment of Diphtheria toxin and has previously been shown to successfully inhibit tumor growth in human clinical study of bladder carcinoma. In a first set of experiments, we examined in vitro efficacy of BC-819 in human lung cancer cell-lines NCI-H460, NCI-H358 and A549, which revealed >90% reduction of cell growth. In vivo efficacy was examined in an orthotopic mouse xenograft lung cancer model and in a lung metastasis model using luminescent A549-C8-luc adenocarcinoma cells. These cells resulted in peri- and intra-bronchiolar tumors upon intrabronchial application and parenchymal tumors upon intravenous injection, respectively. Mice suffering from these lung tumors were treated with BC-819, complexed to branched polyethylenimine (PEI) and aerosolized to the mice once per week for a period of 10 weeks. Using this regimen, growth of intrabronchially induced lung tumors was significantly inhibited (p = 0.01), whereas no effect could be observed in mice suffering from lung metastasis. In summary, we suggest that aerosolized PEI/BC-819 is capable of reducing growth only in tumors arising from the luminal part of the airways and are therefore directly accessible for inhaled BC-819