Echinopsacetylenes A and B, New Thiophenes from <i>Echinops transiliensis</i>

Two new polyacetylene thiophenes, echinopsacetylenes A and B (<b>1</b> and <b>2</b>), were isolated from the roots of <i>Echinops transiliensis</i>. The structures of <b>1</b> and <b>2</b> were elucidated on the basis of spectroscopic analyses and chemical transformations. Echinopsacetylenes A (<b>1</b>) is the first natural product possessing an α-terthienyl moiety covalently linked with another thiophene moiety. Echinopsacetylenes B (<b>2</b>) is the first natural thiophene conjugated with a fatty acid moiety. Echinopsacetylene A (<b>1</b>) showed toxicity against the Formosoan subterranean termite (<i>Coptotermes formosanus</i>)