1,864 research outputs found
High accuracy measure of atomic polarizability in an optical lattice clock
Despite being a canonical example of quantum mechanical perturbation theory,
as well as one of the earliest observed spectroscopic shifts, the Stark effect
contributes the largest source of uncertainty in a modern optical atomic clock
through blackbody radiation. By employing an ultracold, trapped atomic ensemble
and high stability optical clock, we characterize the quadratic Stark effect
with unprecedented precision. We report the ytterbium optical clock's
sensitivity to electric fields (such as blackbody radiation) as the
differential static polarizability of the ground and excited clock levels:
36.2612(7) kHz (kV/cm)^{-2}. The clock's fractional uncertainty due to room
temperature blackbody radiation is reduced an order of magnitude to 3 \times
10^{-17}.Comment: 5 pages, 3 figures, 2 table
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ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervious system
Alternative polyadenylation (APA) has been implicated in a variety of developmental and disease processes. A particularly dramatic form of APA occurs in the developing nervous system of flies and mammals, whereby various developmental genes undergo coordinate 3' UTR extension. In Drosophila, the RNA-binding protein ELAV inhibits RNA processing at proximal polyadenylation sites, thereby fostering the formation of exceptionally long 3' UTRs. Here, we present evidence that paused Pol II promotes recruitment of ELAV to extended genes. Replacing promoters of extended genes with heterologous promoters blocks normal 3' extension in the nervous system, while extension-associated promoters can induce 3' extension in ectopic tissues expressing ELAV. Computational analyses suggest that promoter regions of extended genes tend to contain paused Pol II and associated cis-regulatory elements such as GAGA. ChIP-seq assays identify ELAV in the promoter regions of extended genes. Our study provides evidence for a regulatory link between promoter-proximal pausing and APA
An atomic clock with instability
Atomic clocks have been transformational in science and technology, leading
to innovations such as global positioning, advanced communications, and tests
of fundamental constant variation. Next-generation optical atomic clocks can
extend the capability of these timekeepers, where researchers have long aspired
toward measurement precision at 1 part in . This milestone will
enable a second revolution of new timing applications such as relativistic
geodesy, enhanced Earth- and space-based navigation and telescopy, and new
tests on physics beyond the Standard Model. Here, we describe the development
and operation of two optical lattice clocks, both utilizing spin-polarized,
ultracold atomic ytterbium. A measurement comparing these systems demonstrates
an unprecedented atomic clock instability of after
only hours of averaging
Hyper-Ramsey Spectroscopy of Optical Clock Transitions
We present non-standard optical Ramsey schemes that use pulses individually
tailored in duration, phase, and frequency to cancel spurious frequency shifts
related to the excitation itself. In particular, the field shifts and their
uncertainties of Ramsey fringes can be radically suppressed (by 2-4 orders of
magnitude) in comparison with the usual Ramsey method (using two equal pulses)
as well as with single-pulse Rabi spectroscopy. Atom interferometers and
optical clocks based on two-photon transitions, heavily forbidden transitions,
or magnetically induced spectroscopy could significantly benefit from this
method. In the latter case these frequency shifts can be suppressed
considerably below a fractional level of 10^{-17}. Moreover, our approach opens
the door for the high-precision optical clocks based on direct frequency comb
spectroscopy.Comment: 5 pages, 4 figure
Probing the interiors of the ice giants: Shock compression of water to 700 GPa and 3.8 g/ccm
Recently there has been tremendous increase in the number of identified
extra-solar planetary systems. Our understanding of their formation is tied to
exoplanet internal structure models, which rely upon equations of state of
light elements and compounds like water. Here we present shock compression data
for water with unprecedented accuracy that shows water equations of state
commonly used in planetary modeling significantly overestimate the
compressibility at conditions relevant to planetary interiors. Furthermore, we
show its behavior at these conditions, including reflectivity and isentropic
response, is well described by a recent first-principles based equation of
state. These findings advocate this water model be used as the standard for
modeling Neptune, Uranus, and "hot Neptune" exoplanets, and should improve our
understanding of these types of planets.Comment: Accepted to Phys. Rev. Lett.; supplementary material attached
including 2 figures and 2 tables; to view attachments, please download and
extract the gzipped tar source file listed under "Other formats
Deep far infrared ISOPHOT survey in "Selected Area 57", I. Observations and source counts
We present here the results of a deep survey in a 0.4 sq.deg. blank field in
Selected Area 57 conducted with the ISOPHOT instrument aboard ESAs Infrared
Space Observatory (ISO) at both 60 um and 90 um. The resulting sky maps have a
spatial resolution of 15 x 23 sq.arcsec. per pixel which is much higher than
the 90 x 90 sq.arcsec. pixels of the IRAS All Sky Survey. We describe the main
instrumental effects encountered in our data, outline our data reduction and
analysis scheme and present astrometry and photometry of the detected point
sources. With a formal signal to noise ratio of 6.75 we have source detection
limits of 90 mJy at 60 um and 50 mJy at 90 um. To these limits we find
cumulated number densities of 5+-3.5 per sq.deg. at 60 um and 14.8+-5.0 per
sq.deg.at 90 um. These number densities of sources are found to be lower than
previously reported results from ISO but the data do not allow us to
discriminate between no-evolution scenarios and various evolutionary models.Comment: 15 pages, 11 figures, accepted by Astronomy & Astrophysic
Sub-femtosecond absolute timing precision with a 10 GHz hybrid photonic-microwave oscillator
We present an optical-electronic approach to generating microwave signals
with high spectral purity. By circumventing shot noise and operating near
fundamental thermal limits, we demonstrate 10 GHz signals with an absolute
timing jitter for a single hybrid oscillator of 420 attoseconds (1Hz - 5 GHz)
Separable and Low-Rank Continuous Games
In this paper, we study nonzero-sum separable games, which are continuous
games whose payoffs take a sum-of-products form. Included in this subclass are
all finite games and polynomial games. We investigate the structure of
equilibria in separable games. We show that these games admit finitely
supported Nash equilibria. Motivated by the bounds on the supports of mixed
equilibria in two-player finite games in terms of the ranks of the payoff
matrices, we define the notion of the rank of an n-player continuous game and
use this to provide bounds on the cardinality of the support of equilibrium
strategies. We present a general characterization theorem that states that a
continuous game has finite rank if and only if it is separable. Using our rank
results, we present an efficient algorithm for computing approximate equilibria
of two-player separable games with fixed strategy spaces in time polynomial in
the rank of the game
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