6 research outputs found
Acid-base disorders in critically ill neonates
Objective: To study acid-base imbalance in common pediatric diseases
(such as sepsis, bronchopneumonia, diarrhea, birth-asphyxia etc.) in
neonates. Design and Setting: An observational study was conducted in
an emergency room of a tertiary teaching care hospital in Haryana,
India. Patients and Methods: Fifty neonates (from first hour to one
month) attending pediatric emergency services with various ailments.
Blood gas analysis, electrolytes, plasma lactate, and plasma albumin
were estimated in neonates. Results: Metabolic acidosis was the most
common acid-base disorder. Hyperlactatemia was observed in more than
half of such cases. Birth asphyxia was another common disorder with the
highest mortality in neonates followed by bronchopneumonia and sepsis.
Significant correlation between mortality and critical values of
lactate was observed. Conclusion: Birth asphyxia with high-lactate
levels in neonates constituted major alterations in acid-base disorders
seen in an emergency room of a tertiary teaching care hospital. Plasma
lactate concentration measurement provides an invaluable tool to assess
type of metabolic acidosis in addition to predicting mortality in these
neonates
Acid-base disorders in critically ill neonates
Objective: To study acid-base imbalance in common pediatric diseases
(such as sepsis, bronchopneumonia, diarrhea, birth-asphyxia etc.) in
neonates. Design and Setting: An observational study was conducted in
an emergency room of a tertiary teaching care hospital in Haryana,
India. Patients and Methods: Fifty neonates (from first hour to one
month) attending pediatric emergency services with various ailments.
Blood gas analysis, electrolytes, plasma lactate, and plasma albumin
were estimated in neonates. Results: Metabolic acidosis was the most
common acid-base disorder. Hyperlactatemia was observed in more than
half of such cases. Birth asphyxia was another common disorder with the
highest mortality in neonates followed by bronchopneumonia and sepsis.
Significant correlation between mortality and critical values of
lactate was observed. Conclusion: Birth asphyxia with high-lactate
levels in neonates constituted major alterations in acid-base disorders
seen in an emergency room of a tertiary teaching care hospital. Plasma
lactate concentration measurement provides an invaluable tool to assess
type of metabolic acidosis in addition to predicting mortality in these
neonates