A Rare Case of Bilateral Synchronous Phyllodes Tumor and Triple Negative Breast Cancer

Synchronous breast cancer is a rare event. The majority of cases of synchronous breast cancer will have minor differences in receptor status, but rarely different origins of the tumors. Various breast tumors can have either epithelial or mesenchymal origin and have different treatment strategies and outcomes. In the literature there is a paucity of information regarding the synchronous presentation and treatment of a triple negative invasive ductal carcinoma (TN IDC) and a malignant phyllodes tumor (mPT). This case presentation discusses a 64-year-old woman who presented with a left breast TN IDC and a right breast malignant phyllodes tumor

A Case of Recurrent Breast Cancer Diagnosed from Symptomatic Metastasis to Bladder

Abstract: Women in the United States have an approximate 1 in 8 chance of developing breast cancer in their lifetime. The main cause of death from breast cancer is from metastatic spread of the disease; with the most frequent sites of spread being to the bone, brain, and lungs. The urinary bladder is a rare site of metastasis that has been rarely reported on in the literature. Here we present a case of recurrent metastatic breast cancer found in the urinary bladder without findings of any other sites of metastasis

Re-Excision Rates Following Breast Conserving Therapy: A Single Institutions Experience Over Ten Years

As breast conserving therapy has become the standard of care for patients with early stage breast cancer an area of debate within the surgical literature has been the rate of positive surgical margins requiring re-excision. Nationally re-excision rates are highly variable and have been reported as high as 40%. Any cancer diagnosis and treatment is stressful for patients and having to return to the operating room for a second surgery can greatly affect both patient satisfaction and cosmetic outcomes. Within our institution we wanted to examined our population over ten years undergoing breast conserving therapy to determine our re-excision rates as compared to nationally reported rates. We also wanted to address if following the January of 2013 position statement from the American Society of Breast Surgeons that proposed a treatment algorithm for determining the need for re-excision of surgical margins. We found that our overall re-excision rates were 16%, compared to the national reported rates of 20-40%. Within our patient population we also found that our re-excision rate decreased after January 2013 from 20% to eight percent

Ocular Metastases in Breast Cancer: A Multidisciplinary Approach to Diagnosis and Management

Introduction: Breast cancer is a globally prevalent malignancy with diverse clinical presentations. Understanding metastatic sites like ocular tissues is vital due to their impact on prognosis and treatment strategies. Ocular metastases from breast cancer, though rare, can contribute significantly to metastatic cases. They can even serve as the first sign of advanced disease, highlighting the need for vigilance. Methods: This study utilized a comprehensive literature review to analyze ocular metastases in breast cancer. Cases were examined for time intervals between initial diagnosis and ocular metastasis. The review also assessed manifestations during systemic progression. Methods included patient data analysis, literature synthesis, and case presentation. Results: The analysis showed that 40.4% of patients identified ocular metastasis as their initial sign of advanced breast cancer. Patients exhibited varying time intervals between diagnosis and ocular metastasis, underlining the unpredictable nature of progression. Furthermore, 59.5% developed ocular metastases during systemic progression. This emphasizes the importance of considering ocular symptoms for both early and advanced stages. Conclusion: Breast cancer ocular metastasis presents unique challenges and requires a multidisciplinary approach. Through case presentation, we illustrated the complexity of diagnosis and treatment. Ocular symptoms, even ocular migraines, should raise suspicion of metastasis. Collaboration among specialists, along with advanced imaging and tailored therapies, is crucial for accurate staging and treatment. Continued research and multidisciplinary efforts are vital for improved patient outcomes