18 research outputs found
Influence of the sulfur vacancies on the electronic properties of In16Sn4S32
cited By 5International audienceHigh and low temperature forms of In16Sn4S32 differ in color (black and orange-red, respectively) and lithium insertion properties. We have studied both forms by X-ray and neutron diffraction techniques and 119Sn Mössbauer spectroscopy. While diffraction techniques show no structural difference, Mössbauer spectra allow to differentiate both phases, as a consequence of the presence of SnI1 in the high-temperature form. We show from tight-binding calculations that both the differences in color and the tin oxidation states are related to the existence of sulfur vacancies in the local environment of the tin atoms. © 2001 Éditions scientifiques et médicales Elsevier SAS
Bonding in skutterudites : combined experimental and theoretical characterization of CoSb3
Concentration in the Belgian Brewing Industry and the Breakthrough of Lager in the Interwar Years
Micro/nano-structured SnS2 negative electrodes using chitosan derivatives as water-soluble binders for Li-ion batteries
Zinc Oxide Nanorods Shielded with an Ultrathin Nickel Layer: Tailoring of Physical Properties
Keratinocyte-specific ablation of the NF-kappa B regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
The ubiquitin-editing enzyme A20 (tumor necrosis factor-alpha-induced protein 3) serves as a critical brake on nuclear factor kappa B (NF-kappa B) signaling. In humans, polymorphisms in or near the A20 gene are associated with several inflammatory disorders, including psoriasis. We show here that epidermis-specific A20-knockout mice (A20(EKO)) develop keratinocyte hyperproliferation, but no signs of skin inflammation, such as immune cell infiltration. However, A20(EKO) mice clearly developed ectodermal organ abnormalities, including disheveled hair, longer nails and sebocyte hyperplasia. This phenotype resembles that of mice overexpressing ectodysplasin-A1 (EDA-A1) or the ectodysplasin receptor (EDAR), suggesting that A20 negatively controls EDAR signaling. We found that A20 inhibited EDAR-induced NF-kappa B signaling independent from its de-ubiquitinating activity. In addition, A20 expression was induced by EDA-A1 in embryonic skin explants, in which its expression was confined to the hair placodes, known to be the site of EDAR expression. In summary, our data indicate that EDAR-induced NF-kappa B levels are controlled by A20, which functions as a negative feedback regulator, to assure proper skin homeostasis and epidermal appendage development. Cell Death and Differentiation (2011) 18, 1845-1853; doi:10.1038/cdd.2011.55; published online 13 May 201
Keratinocyte-specific ablation of the NF-ÎşB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
Archéologie de l’espace urbain
L'archéologie urbaine est dans un rapport dialectique constant entre les échelles de la fouille et de l'espace urbanisé ancien. D'une part les archives du sol centrent l'approche sur la matérialité de la ville, d'autre part l'histoire du rapport entre espace et société urbaine mobilise toutes les sources disponibles. La finalité est la compréhension des processus de fabrique et de transformation de l'espace urbain par les sociétés. Les méthodes mises en œuvre sont celles des sciences sociales, parmi lesquelles la géographie qui a eu une influence notable sur la perception, par les archéologues, du rapport des sociétés à l'espace. À travers une approche diachronique, cet ouvrage présente dans un premier temps une série de villes comme autant de cas particuliers dont la connaissance intrinsèque de l'espace urbain a été renouvelée. La deuxième partie porte sur un ensemble d'études des transformations de l'espace urbain. Enfin, la dernière partie propose des modélisations permettant d'aborder les trajectoires et les interactions multi-scalaires entre villes et systèmes de villes. Plus que jamais, la mise en œuvre de programmes d'archéologie urbaine est la clef de l'anticipation nécessaire à la prise en compte de la connaissance historique dans les projets urbains
Enterprise architecture for small and medium-sized enterprises: a starting point for bringing EA to SMEs, based on adoption models
Enterprise architecture (EA) is used as a holistic approach to keep things aligned in a company. Some emphasize the use of EA to align IT with the business, others see it broader and use it to also keep the processes aligned with the strategy. EA has gained importance in larger companies. Although a lot of research is being done on EA, still hardly anything is known about its use in the context of a small and medium-sized enterprise (SME). Although EA can offer a lot of benefits to SMEs, still hardly any SME uses EA. In this paper, the authors analyze both SMEs and EA techniques and investigate the adoption of EA in SMEs. At the end of the chapter, some guidelines for EA technique developers are proposed