The new Sunspot Number: assembling all corrections

The Sunspot Number, created by R.Wolf in 1849, provides a direct long-term record of solar activity from 1700 to the present. In spite of its central role in multiple studies of the solar dynamo and of the past Sun-Earth relations, it was never submitted to a global critical revision. However, various discrepancies with other solar indices recently motivated a full re-calibration of this series. Based on various diagnostics and corrections established in the framework of several Sunspot Number Workshops and described in Clette et al. 2014, we assembled all corrections in order to produce a new standard version of this reference time series. In this paper, we explain the three main corrections and the criteria used to choose a final optimal version of each correction factor or function, given the available information and published analyses. We then discuss the good agreement obtained with the Group sunspot Number derived from a recent reconstruction. Among the implications emerging from this re-calibrated series, we also discuss the absence of a rising secular trend in the newly-determined solar cycle amplitudes, also in relation with contradictory indications derived from cosmogenic radionuclides. As conclusion, we introduce the new version management scheme now implemented at the World Data Center - SILSO, which reflects a major conceptual transition: beyond the re-scaled numbers, this first revision of the Sunspot Number also transforms the former locked data archive into a living observational series open to future improvements

The revised Brussels-Locarno Sunspot Number (1981-2015)

In 1981, the production of the international Sunspot Number moved from the Z\"{u}rich Observatory to the Royal Observatory of Belgium, marking a very important transition in the history of the Sunspot Number. Those recent decades are particularly important for linking recent modern solar indices and fluxes and the past Sunspot Number series. However, large variations have been recently identified in the scale of the Sunspot Number between 1981 and the present. Here, we reconstruct a new average Sunspot Number series $S_N$ using long-duration stations between 1981 and 2015. We also extend this reconstruction using long-time series from 35 stations over 1945-2015, which includes the 1981 transition. In both reconstructions, we also derive a parallel Group Number series $G_N$. Our results confirm the variable trends of the Locarno pilot station. We also verify the scale of the resulting 1981-2015 correction factor relative to the preceding period 1945--1980. By comparing the new $S_N$ and $G_N$ series, we find that a constant quadratic relation exists between those two indices. This proxy relation leads to a fully constant and cycle-independent $S_N/G_N$ ratio over cycles 19 to 23, with the exception of cycle 24. We find a very good agreement between our reconstructed $G_N$ and the new "backbone" Group Number but inhomogeneities in the original Group Number as well as the $F_{10.7}$ radio flux and the American sunspot number $R_a$. This analysis opens the way to the implementation of a more advanced method for producing the Sunspot Number in the future. In particular, we identify the existence of distinct subsets of observing stations sharing very similar personal k factors, which may be a key element for building a future multi-station reference in place of the past single pilot station.Comment: 33 pages, 23 figures, 2 table

Multi-species summer cover crop in protected vegetable systems (DiverIMPACTS Practice Abstract)

This cover crop mixture provides biomass which is crushed and incorporated into the soil. Benefits include improved organic matter and soil structure, reduced risk of nitrogen leaching (the C/N ratio of the cover crop ranges from 10 to 40) and improved weed, pest and disease management. Cover crop mixture botanical families should differ from that of the vegetables to increase rotation diversity and contribute to the management of soilborne pathogens

Nonparametric monitoring of sunspot number observations: a case study

Solar activity is an important driver of long-term climate trends and must be accounted for in climate models. Unfortunately, direct measurements of this quantity over long periods do not exist. The only observation related to solar activity whose records reach back to the seventeenth century are sunspots. Surprisingly, determining the number of sunspots consistently over time has remained until today a challenging statistical problem. It arises from the need of consolidating data from multiple observing stations around the world in a context of low signal-to-noise ratios, non-stationarity, missing data, non-standard distributions and many kinds of errors. The data from some stations experience therefore severe and various deviations over time. In this paper, we propose the first systematic and thorough statistical approach for monitoring these complex and important series. It consists of three steps essential for successful treatment of the data: smoothing on multiple timescales, monitoring using block bootstrap calibrated CUSUM charts and classifying of out-of-control situations by support vector techniques. This approach allows us to detect a wide range of anomalies (such as sudden jumps or more progressive drifts), unseen in previous analyses. It helps us to identify the causes of major deviations, which are often observer or equipment related. Their detection and identification will contribute to improve future observations. Their elimination or correction in past data will lead to a more precise reconstruction of the world reference index for solar activity: the International Sunspot Number.Comment: 27 pages (without appendices), 6 figure

Selective versus hyperselective posterior fusions in Lenke 5 adolescent idiopathic scoliosis: comparison of radiological and clinical outcomes

PURPOSE: Recent literature has reported that the ]progression risk of Lenke 5 adolescent idiopathic scoliosis (AIS) during adulthood had been underestimated. Surgery is, therefore, proposed more to young patients with progressive curves. However, choice of the approach and fusion levels remains controversial. The aim of this study was to analyze the influence of the length of posterior fusion on clinical and radiological outcomes in Lenke 5 AIS. METHODS: All Lenke 5 AIS operated between 2008 and 2012 were included with a minimum 2-year follow-up. Patients were divided into two groups according to the length of fusion. In the first group (selective), the upper instrumented level (UIV) was the upper end vertebra of the main structural curve and distally the fusion was extended to the stable and neutral vertebra, according to Lenke's classification. In the second group (hyperselective), shorter fusions were performed and the number of levels fused depended on the location of the apex of the curve (at maximum, 2 levels above and below, according to Hall's criteria). Apart from the fusion level selection, the surgical procedure was similar in both groups. Radiological outcomes and SRS-22 scores were reported. RESULTS: 78 patients were included (35 selective and 43 hyperselective). The number of levels fused was significantly higher in the first group (7.8 ± 3 vs 4.3 ± 0.6). None of the patients was fused to L4 in selective group. No correlation was found between length of fusion and complication rate. Eight patients had adding-on phenomenon among which 6 (75%) had initially undergone hyperselective fusions and had significantly higher postoperative lower instrumented vertebra (LIV) tilt. In the adding-on group, LIV was located above the last touching vertebra (LTV) in 62.5% of the cases and above the stable vertebra (SV) in 87.5%. Patients in the selective group reported a significantly lower score in the SRS function domain. CONCLUSION: Coronal alignment was restored in both groups. Hyperselective posterior fusions can be considered in Lenke 5 AIS, preserving one or two mobile segments, with similar clinical and radiological outcomes. However, selection of the LIV according to SV and LTV need to be accurately analyzed in order to avoid adding-on during follow-up

Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations

Hematopoietic stem cells are responsible for life-long blood cell production and are highly sensitive to exogenous stresses. The effects of low doses of ionizing radiations on radiosensitive tissues such as the hematopoietic tissue are still unknown despite their increasing use in medical imaging. Here, we study the consequences of low doses of ionizing radiations on differentiation and self-renewal capacities of human primary hematopoietic stem/progenitor cells (HSPC). We found that a single 20 mGy dose impairs the hematopoietic reconstitution potential of human HSPC but not their differentiation properties. In contrast to high irradiation doses, low doses of irradiation do not induce DNA double strand breaks in HSPC but, similar to high doses, induce a rapid and transient increase of reactive oxygen species (ROS) that promotes activation of the p38MAPK pathway. HSPC treatment with ROS scavengers or p38MAPK inhibitor prior exposure to 20 mGy irradiation abolishes the 20 mGy-induced defects indicating that ROS and p38MAPK pathways are transducers of low doses of radiation effects. Taken together, these results show that a 20 mGy dose of ionizing radiation reduces the reconstitution potential of HSPC suggesting an effect on the self-renewal potential of human hematopoietic stem cells and pinpointing ROS or the p38MAPK as therapeutic targets. Inhibition of ROS or the p38MAPK pathway protects human primary HSPC from low-dose irradiation toxicity

Conservative treatment of pediatric thoracic and lumbar spinal fractures

To assess sagittal plane spinopelvic balance and functional outcomes in a pediatric cohort of patients with a thoracic and/or a lumbar fracture treated conservatively. A multicentric study retrospectively reviewed radiological and functional outcomes (mean follow-up 49 months) of 48 patients (mean age 12 years) with thoracic and/or lumbar spinal fractures that occurred between 1996 and 2014. Demographic data and radiological spinopelvic parameters were analyzed. Functional outcome was evaluated by a telephone interview. First, a comparison between the initial and the last follow-up full-spine radiographs was performed for the assessment of bone remodeling and sagittal plane balance. Then, patients were classified into two groups (group 1: Risser≤2 and group 2, Risser>2) to assess the influence of skeletal maturity on the restoration of a correct sagittal balance. A total of 62% of the patients were at skeletal maturity at the final follow-up (Risser 4 and 5). Patients with a Risser grade of 2 or less had a higher remodeling potential. The mean residual local kyphosis in thoracic and lumbar fractures was, respectively, 8.2° and 8.7°. The mean thoracic global kyphosis remains stable at the last follow-up, in contrast to lumbar lordosis, which increased significantly. Sagittal plane global measurements on the basis of the C7-plumbline remained unchanged at the last follow-up. There was no change in the pelvic parameters, except for the sacral slope in the group 1 for patients with a lumbar fracture. The current study confirms a greater correction in younger patients (Risser≤2) in spinal fractures and reported that thoracic fractures have a higher remodeling potential than lumbar fracture. A local kyphosis of almost 10° remained at the last follow-up. However, no deterioration in the sagittal plane balance was found. This suggests compensatory mechanisms in adjacent structures for children and adolescents and excludes the only hypothesis of bone remodeling

Elements of morphology: Standard terminology for the teeth and classifying genetic dental disorders

Dental anomalies occur frequently in a number of genetic disorders and act as major signs in diagnosing these disorders. We present definitions of the most common dental signs and propose a classification usable as a diagnostic tool by dentists, clinical geneticists, and other health care providers. The definitions are part of the series Elements of Morphology and have been established after careful discussions within an international group of experienced dentists and geneticists. The classification system was elaborated in the French collaborative network 'TÊTECOU' and the affiliated O-Rares reference/competence centers. The classification includes isolated and syndromic disorders with oral and dental anomalies, to which causative genes and main extraoral signs and symptoms are added. A systematic literature analysis yielded 408 entities of which a causal gene has been identified in 79%. We classified dental disorders in eight groups: dental agenesis, supernumerary teeth, dental size and/or shape, enamel, dentin, dental eruption, periodontal and gingival, and tumor-like anomalies. We aim the classification to act as a shared reference for clinical and epidemiological studies. We welcome critical evaluations of the definitions and classification and will regularly update the classification for newly recognized conditions