7,675 research outputs found

    Comparison of Support Vector Machine and Back Propagation Neural Network in Evaluating the Enterprise Financial Distress

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    Recently, applying the novel data mining techniques for evaluating enterprise financial distress has received much research alternation. Support Vector Machine (SVM) and back propagation neural (BPN) network has been applied successfully in many areas with excellent generalization results, such as rule extraction, classification and evaluation. In this paper, a model based on SVM with Gaussian RBF kernel is proposed here for enterprise financial distress evaluation. BPN network is considered one of the simplest and are most general methods used for supervised training of multilayered neural network. The comparative results show that through the difference between the performance measures is marginal; SVM gives higher precision and lower error rates.Comment: 13 pages, 1 figur

    On Stochastic Subgradient Mirror-Descent Algorithm with Weighted Averaging

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    This paper considers stochastic subgradient mirror-descent method for solving constrained convex minimization problems. In particular, a stochastic subgradient mirror-descent method with weighted iterate-averaging is investigated and its per-iterate convergence rate is analyzed. The novel part of the approach is in the choice of weights that are used to construct the averages. Through the use of these weighted averages, we show that the known optimal rates can be obtained with simpler algorithms than those currently existing in the literature. Specifically, by suitably choosing the stepsize values, one can obtain the rate of the order 1/k1/k for strongly convex functions, and the rate 1/k1/\sqrt{k} for general convex functions (not necessarily differentiable). Furthermore, for the latter case, it is shown that a stochastic subgradient mirror-descent with iterate averaging converges (along a subsequence) to an optimal solution, almost surely, even with the stepsize of the form 1/1+k1/\sqrt{1+k}, which was not previously known. The stepsize choices that achieve the best rates are those proposed by Paul Tseng for acceleration of proximal gradient methods

    Streamlines for Motion Planning in Underwater Currents

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    Motion planning for underwater vehicles must consider the effect of ocean currents. We present an efficient method to compute reachability and cost between sample points in sampling-based motion planning that supports long-range planning over hundreds of kilometres in complicated flows. The idea is to search a reduced space of control inputs that consists of stream functions whose level sets, or streamlines, optimally connect two given points. Such stream functions are generated by superimposing a control input onto the underlying current flow. A streamline represents the resulting path that a vehicle would follow as it is carried along by the current given that control input. We provide rigorous analysis that shows how our method avoids exhaustive search of the control space, and demonstrate simulated examples in complicated flows including a traversal along the east coast of Australia, using actual current predictions, between Sydney and Brisbane.Comment: 7 pages, 4 figures, accepted to IEEE ICRA 2019. Copyright 2019 IEE

    Receptor oligomerization: from early evidence to current understanding in class B GPCRs

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    Dimerization or oligomerization of G protein-coupled receptors (GPCRs) are known to modulate receptor functions in terms of ontogeny, ligand-oriented regulation, pharmacological diversity, signal transduction, and internalization. Class B GPCRs are receptors to a family of hormones including secretin, growth hormone-releasing hormone, vasoactive intestinal polypeptide and parathyroid hormone, among others. The functional implications of receptor dimerization have extensively been studied in class A GPCRs, while less is known regarding its function in class B GPCRs. This article reviews receptor oligomerization in terms of the early evidence and current understanding particularly of class B GPCRs.published_or_final_versio

    Structural and functional divergence of growth hormone-releasing hormone receptors in early sarcopterygians: lungfish and Xenopus

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    The evolutionary trajectories of growth hormone-releasing hormone (GHRH) receptor remain enigmatic since the discovery of physiologically functional GHRH-GHRH receptor (GHRHR) in non-mammalian vertebrates in 2007. Interestingly, subsequent studies have described the identification of a GHRHR2 in chicken in addition to the GHRHR and the closely related paralogous receptor, PACAP-related peptide (PRP) receptor (PRPR). In this article, we provide information, for the first time, on the GHRHR in sarcopterygian fish and amphibians by the cloning and characterization of GHRHRs from lungfish (P. dolloi) and X. laevis. Sequence alignment and phylogenetic analyses demonstrated structural resemblance of lungfish GHRHR to their mammalian orthologs, while the X. laevis GHRHR showed the highest homology to GHRHR2 in zebrafish and chicken. Functionally, lungfish GHRHR displayed high affinity towards GHRH in triggering intracellular cAMP and calcium accumulation, while X. laevis GHRHR2 was able to react with both endogenous GHRH and PRP. Tissue distribution analyses showed that both lungfish GHRHR and X. laevis GHRHR2 had the highest expression in brain, and interestingly, X. laevis GHRHR2 also had high abundance in the reproductive organs. These findings, together with previous reports, suggest that early in the Sarcopterygii lineage, GHRHR and PRPR have already established diverged and specific affinities towards their cognate ligands. GHRHR2, which has only been found in xenopus, zebrafish and chicken hitherto, accommodates both GHRH and PRP.published_or_final_versio

    Serdexmethylphenidate/Dexmethylphenidate – A Promising Treatment Option for Childhood Attention Deficit Hyperactivity Disorder (ADHD)

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    To review the phase 2 and phase 3 clinical trials of Serdexmethylphenidate and dexmethylphenidate (SDX/d-MPH) in the treatment of Attention Deficit/Hyperactivity disorder (ADHD) in children

    Design of the freeform V-cut optics in the cell phone backlight system

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