54 research outputs found

    A complete solution of a Constrained System: SUSY Monopole Quantum Mechanics

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    We solve the quantum mechanical problem of a charged particle on S^2 in the background of a magnetic monopole for both bosonic and supersymmetric cases by constructing Hilbert space and realizing the fundamental operators obeying complicated Dirac bracket relations in terms of differential operators. We find the complete energy eigenfunctions. Using the lowest energy eigenstates we count the number of degeneracies and examine the supersymmetric structure of the ground states in detail.Comment: 20 pages including the title, prepared in JHEP forma

    Risk of all-cause and cause-specific mortality associated with immune-mediated inflammatory diseases in Korea

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    ObjectiveImmune-mediated inflammatory disease (IMID) is associated with an increased risk of mortality. It is unclear whether the higher mortality is attributable to the IMIDs themselves or to the higher prevalence of comorbidities in IMIDs. We aimed to investigate whether IMIDs per se confer a higher risk of mortality.MethodsFrom the Korean National Health Insurance Service-National Sample Cohort database, this population-based cohort study included 25,736 patients newly diagnosed with IMIDs between January 2007 and December 2017, and 128,680 individuals without IMIDs who were matched for age, sex, income, hypertension, type 2 diabetes, dyslipidemia, and the Charlson comorbidity index. All individuals were retrospectively observed through December 31, 2019. The outcomes included all-cause and cause-specific mortalities. Adjustments for age, sex, and comorbidities were performed using multivariable Cox proportional hazard regression analyses, and adjusted hazard ratios (aHRs) with 95% confidence intervals (CIs) for the outcomes were estimated.ResultsThe adjusted risk of all-cause mortality was significantly lower in patients with IMIDs than that in those without (aHR, 0.890; 95% CI, 0.841–0.942). Regarding cause-specific mortality, cancer-specific (aHR, 0.788; 95% CI, 0.712–0.872) and cardiovascular disease-specific (aHR, 0.798; 95% CI, 0.701–0.908) mortalities were the two causes of death that showed significantly lower risks in patients with IMIDs. A similar trend was observed when organ based IMIDs were analyzed separately (i.e., gut, joint, and skin IMIDs).ConclusionAfter adjusting for comorbidities, IMIDs were associated with a lower risk of all-cause mortality compared to those without IMIDs. This was attributable to the lower risks of cancer-and cardiovascular disease-specific mortalities

    The Expression Patterns of FAM83H and PANX2 Are Associated With Shorter Survival of Clear Cell Renal Cell Carcinoma Patients

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    FAM83H is primarily known for its role in amelogenesis; however, recent reports suggest FAM83H might be involved in tumorigenesis. Although the studies of FAM83H in kidney cancer are limited, a search of the public database shows a significant association between FAM83H and pannexin-2 (PANX2) in clear cell renal cell carcinomas (CCRCCs). Therefore, we evaluated the clinicopathological significance of the immunohistochemical expression of FAM83H and PANX2 in 199 CCRCC patients. The expression of FAM83H and PANX2 were significantly associated with each other. In univariate analysis, individual, and co-expression pattern of FAM83H and PANX2 was significantly associated with shorter overall survival (OS) and relapse-free survival (RFS) of CCRCC patients: nuclear expression of FAM83H (OS; P < 0.001, RFS; P < 0.001), cytoplasmic expression of FAM83H (OS; P < 0.001, RFS; P < 0.001), nuclear expression of PANX2 (OS; P < 0.001, RFS; P < 0.001), cytoplasmic expression of PANX2 (OS; P < 0.001, RFS; P < 0.001), co-expression pattern of nuclear FAM83H and nuclear PANX2 (OS; P < 0.001, RFS; P < 0.001). In multivariate analysis, nuclear expression of FAM83H (OS; P < 0.001, RFS; P = 0.003) and the co-expression pattern of nuclear FAM83H and PANX2 (OS; P < 0.001, RFS; P < 0.001) were independent indicators of shorter survival of CCRCC patients. Cytoplasmic expression of FAM83H was associated with shorter RFS (P = 0.030) in multivariate analysis. In Caki-1 and Caki-2 CCRCC cells, knock-down of FAM83H decreased PANX2 expression and cell proliferation, and overexpression of FAM83H increased PANX2 expression and cell proliferation. These results suggest that FAM83H and PANX2 might be involved in the progression of CCRCC in a co-operative manner, and their expression might be used as novel prognostic indicators for CCRCC patients

    ZrB2– SiC nano-powder mixture prepared using ZrSi2 and modified spark plasma sintering

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    ZrB2SiC nano-powder mixture was synthesized using ZrSi2 source material and a modified spark plasma sintering apparatus. The particle size of ZrB2 and SiC was about 80 and 20nm, respectively. The molecular-level homogeneity of Zr/Si source and fast heating/cooling rate by SPS caused the formation of homogeneously intermixed nano-powders. A strong exothermal reaction occurred at around 860 degrees C, which caused strong agglomeration and growth of the synthesized powder mixture. The rapid reaction could be controlled by adding 20wt% of NaCl, which acted as an inert filler.118sciescopu

    Community patchwork.

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    The report comprising of the photography, writing and production of the Cimmunity Centres/Clubs (CCs) in Singapore.Bachelor of Communication Studie

    Case Studies and Challenges of Implementing Geotechnical Building Information Modelling in Malaysia

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    Unforeseen ground conditions are some of the main contributors to construction cost over-runs and late completion. Recent research trends have witnessed the scopes of building information modeling (BIM) technology being extended to subsoil and substructure constructions, or simply known as geotechnical BIM. This paper aimed to explore the procedures of developing 3D subsoil models through two case studies in Malaysia. The geotechnical BIM processes were performed by commercial software, AutoCAD Civil 3D 2017, with the extension of the Geotechnical Module. The modeling procedures can be divided into three main stages, namely data collection, data interpretation, and data visualization. The subsoil models were successfully developed at different levels of detailing to serve for different applications. The results showed that the 3D subsoil modeling required huge modeling and computational efforts, particularly when dealing with tropical residual soil profiles in Malaysia that are highly intricate. Thus, an adequate soil strata generalization was required to simplify the generated subsoil model. Data collection and management was identified as one of the main challenges of promoting geotechnical BIM in Malaysia at a macro-scale. Despite the challenges, successful implementation of the geotechnical building information in the present case studies were proved to be capable of promoting interoperability of soil data, which is an essential element in sustainable construction

    Concomitant removal of NOx and SOx from a pressurized oxy-fuel combustion process using a direct contact column

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    The simultaneous removal of NO x and SO x using a direct contact column has potential for efficient treatment of the flue gases arising from pressurized oxy-fuel combustion. This study focuses on a parametric analysis of the efficiency of NO x and SO x removal from the flue gas of an oxy-fuel combustion process using an Aspen Plus direct contact column model. The chemistry implemented in this model reflects the state-of-the-art NO x and SO x reaction mechanisms, with particular emphasis on the liquid-phase chemistry, including pH-dependency. The effects of pressure, water flow rate, and recycle ratio on the removal efficiencies of NO x and SO x were evaluated. The evaluation was conducted based on the base case pressurized (15 bar) flue gas with a feed rate of 120 kg/s and inlet temperature of 40 \ub0C before it was supplied to the column. NO x removal efficiency increased from 70% to 97% when the pressure increased from 15 bar to 30 bar, whereas 99.9% of the SO 2 was absorbed from the flue gas at 15 bar. We show that the removal efficiency is pH-sensitive and it is directly influenced by the recycle ratio and liquid-to-gas ratio (L/G). As the L/G ratio was increased, the removal efficiency of SO x and NO x increased. On the other hand, when the recycle ratio of bottom liquid was increased, the removal efficiency of SO x and NO x decreased
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