1,056 research outputs found

    Towards real-world complexity: an introduction to multiplex networks

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    Many real-world complex systems are best modeled by multiplex networks of interacting network layers. The multiplex network study is one of the newest and hottest themes in the statistical physics of complex networks. Pioneering studies have proven that the multiplexity has broad impact on the system's structure and function. In this Colloquium paper, we present an organized review of the growing body of current literature on multiplex networks by categorizing existing studies broadly according to the type of layer coupling in the problem. Major recent advances in the field are surveyed and some outstanding open challenges and future perspectives will be proposed.Comment: 20 pages, 10 figure

    The Injectable rhBMP-2-containing Collagen Gel for Tendon Healing in a Rabbit Extra-Articular Bone Tunnel Model

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    This rabbit animal study has a hypothesis that the collagen gel, which is injectable easily, can be an effective carrier for recombinant human bone morphogenetic protein 2 (rhBMP-2) for the tendon healing in a bone tunnel. The cut upper long digital extensor tendon of each rabbit was inserted into the proximal tibia bone tunnel, and rhBMP-2 conjugated collagen gel was injected into the tendon-bone tunnel interface using a syringe. Biomechanical and histological performances were analyzed at 3 and 6 weeks after surgery. The collagen sol at room temperature was transformed to a gel at 37°C. The rhBMP-2 was slowly released from the collagen gel for more than 4 weeks. The in vivo experiment showed the enhanced new fibrocartilage and bone tissue formation at 6 weeks after injecting the rhBMP-2-containing collagen gel. The calcification and enthesis-like tissue were detected radiologically in the repaired tendon-bone junction. The viscous collagen gel-containing rhBMP-2 increased the fusion rate of the repaired tendon in the bone tunnel. This study showed that viscous collagen gel can be an effective carrier for rhBMP-2 for tendon healing in the bone tunnel. The rhBMP-2-containing collagen gel will be promising for tendon-bone interface healing in the future

    rhBMP-2-Coated Acellular Dermal Graft for Chronic Rotator Cuff Healing: Translational Tendon Repair Research

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    A rotator cuff tear is a common shoulder injury in sports medicine. However, a rotator cuff repair still has the high failure rate (57%) in large torn (>8 cm2) rotator cuff cases. One of the main reasons is failing at suture-tendon cause of continuous tensional and torsional stresses even after surgery, and thus, an ideal biologic augmentation to overcome large tears is an essential challenge. The ECM graft, the biological material can be useful for augment repair of large torn rotator cuff. Recombinant human bone morphogenetic protein 2 (rhBMP-2), which belongs to transforming growth factor-β superfamily, is well known as an osteoinductive growth factor. It plays an important role in the development of bone and cartilage. rhBMP-2 also facilitates chemotaxis in the host tissue. In this study, rhBMP-2-coated acellular dermal graft, which is isolated from human cadaveric donor, was transplanted in the rabbit with the chronic rotator cuff injury. The radiologic image, histomorphometric, histologic image analyses, and tensile test were performed to evaluate the effectiveness. The results showed the enhancement of increased host cell infiltration, new bone formation, and tensile mechanical property. The rhBMP-2-coated acellular dermal graft will be promising for chronic rotator cuff healing

    Radiative transfer in disc galaxies −- V. The accuracy of the KB approximation

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    We investigate the accuracy of an approximate radiative transfer technique that was first proposed by Kylafis & Bahcall (hereafter the KB approximation) and has been popular in modelling dusty late-type galaxies. We compare realistic galaxy models calculated with the KB approximation with those of a three-dimensional Monte Carlo radiative transfer code SKIRT. The SKIRT code fully takes into account of the contribution of multiple scattering whereas the KB approximation calculates only single scattered intensity and multiple scattering components are approximated. We find that the KB approximation gives fairly accurate results if optically thin, face-on galaxies are considered. However, for highly inclined (i≳85∘i \gtrsim 85^{\circ}) and/or optically thick (central face-on optical depth ≳1\gtrsim1) galaxy models, the approximation can give rise to substantial errors, sometimes, up to ≳40%\gtrsim 40\%. Moreover, it is also found that the KB approximation is not always physical, sometimes producing infinite intensities at lines of sight with high optical depth in edge-on galaxy models. There is no "simple recipe" to correct the errors of the KB approximation that is universally applicable to any galaxy models. Therefore, it is recommended that the full radiative transfer calculation be used, even though it's slower than the KB approximation.Comment: 10 pages, 6 figures, accepted for publication in MNRA

    Robust Digital Predistortion in Saturation Region of Power Amplifiers

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    This paper proposes a digital predistortion (DPD) technique to improve linearization performance when the power amplifier (PA) is driven near the saturation region. The PA is a non-linear device in general, and the nonlinear distortion becomes severer as the output power increases. However, the PA’s power efficiency increases as the PA output power increases. The nonlinearity results in spectral regrowth, which leads to adjacent channel interference, and degrades the transmit signal quality. According to our simulation, the linearization performance of DPD is degraded abruptly when the PA operates in its saturation region. To relieve this problem, we propose an improved DPD technique. The proposed technique performs on/off control of the adaptive algorithm based on the magnitude of the transmitted signal. Specifically, the adaptation normally works for small and medium signals while it stops for large signals. Therefore, harmful coefficient updates by saturated signals can be avoided. A computer simulation shows that the proposed method can improve the linearization performance compared with the conventional DPD method in highly driven PAs
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