Self-Compassion and Depression Across Culture: Comparisons of Emerging Adults in China and the United States

Major Depressive Disorder (MDD) is one of the most common mood disorders and affects over 300 million individuals across the world in a given year. MDD is marked by sadness, loss of pleasure or interest, feelings of guilt or low self-worth, disturbed sleep or appetite, fatigue or loss of energy, and poor concentration that leads to functional impairment, which can potentially have a debilitating impact on individual’s educational, occupational, social and psychological areas of life. Not only is depression highly prevalent in the U.S., but it is also a global concern, including countries such as China. Estimates of lifetime prevalence rates range from 32.6 to 35.1 million in the US and 54 to 100 million in China, respectively. A growing literature shows that self-compassion is a strong protective factor for depression. Self-compassion is a process of mindfully accepting oneself by reducing self-criticism and examining one’s experiences from a broader perspective. The values behind self-compassion are rooted in Asian cultural teachings. A small but growing body of work suggests that self-compassion outcomes may differ across non-Western and Western cultures. However, the effect of cultural background on the relationship between self-compassion and depression remains unknown; therefore, more research is needed to be done in cross-cultural domains. The current proposed project further seeks to understand the role of self-compassion in depression among both American and Chinese populations. This study also aims to understand whether cultural components moderate the relationship between self-compassion and depression

Development and validation of the digestive function assessment instrument for traditional korean medicine: Sasang digestive function inventory

Objective. This study was conducted for development and validation of the Sasang Digestive Function Inventory (SDFI) with type-specific digestive function-related symptoms for identification of Sasang type and pathological pattern. Methods and Materials. We selected questionnaire items for pathophysiological symptoms using internal consistency analysis and examined construct validity using 193 healthy participants. Test-retest reliability with a four-week interval as well as convergent validity was examined using the Nepean Dyspepsia Index-Korean (NDIK), Functional Dyspepsia-Related Quality of Life (FDQOL), Dutch Eating Behavior Questionnaire (DEBQ), and Body Mass Index (BMI). Results. The 21-item SDFI showed satisfactory internal consistency (Cronbach’s alpha = 0.743) and test-retest reliability (, ). Three extracted subscales, SDFI-Digestion, SDFI-Appetite, and SDFI-Eating pattern, explained 56.02% of the total variance. The SDFI showed significant () correlation with total symptom score of NDIK, FDRQOL-Eating status, DEBQ-External Eating scale, and BMI. The SDFI score of the Tae-Eum () type was significantly () larger than that of the So-Eum () type. Conclusion. Current results demonstrated the reliability and validity of the SDFI and its subscales, which can be utilized as an objective instrument for diagnosis of Sasang types and assessment of the type-specific digestive function

Photometric defocus observations of transiting extrasolar planets

We have carried out photometric follow-up observations of bright transiting extrasolar planets using the CbNUOJ 0.6m telescope. We have tested the possibility of obtaining high photometric precision by applying the telescope defocus technique allowing the use of several hundred seconds in exposure time for a single measurement. We demonstrate that this technique is capable of obtaining a root-mean-square scatter of order sub-millimagnitude over several hours for a V $\sim$ 10 host star typical for transiting planets detected from ground-based survey facilities. We compare our results with transit observations with the telescope operated in in-focus mode. High photometric precision is obtained due to the collection of a larger amount of photons resulting in a higher signal compared to other random and systematic noise sources. Accurate telescope tracking is likely to further contribute to lowering systematic noise by probing the same pixels on the CCD. Furthermore, a longer exposure time helps reducing the effect of scintillation noise which otherwise has a significant effect for small-aperture telescopes operated in in-focus mode. Finally we present the results of modelling four light-curves for which a root-mean-square scatter of 0.70 to 2.3 milli-magnitudes have been achieved.Comment: 12 pages, 11 figures, 5 tables. Submitted to Journal of Astronomy and Space Sciences (JASS

Two distinct red giant branch populations in the globular cluster NGC 2419 as tracers of a merger event in the Milky Way

Recent spectroscopic observations of the outer halo globular cluster (GC) NGC 2419 show that it is unique among GCs, in terms of chemical abundance patterns, and some suggest that it was originated in the nucleus of a dwarf galaxy. Here we show, from the Subaru narrow-band photometry employing a calcium filter, that the red giant-branch (RGB) of this GC is split into two distinct subpopulations. Comparison with spectroscopy has confirmed that the redder RGB stars in the $hk$[=(Ca$-b)-(b-y)$] index are enhanced in [Ca/H] by $\sim$0.2 dex compared to the bluer RGB stars. Our population model further indicates that the calcium-rich second generation stars are also enhanced in helium abundance by a large amount ($\Delta$Y = 0.19). Our photometry, together with the results for other massive GCs (e.g., $\omega$ Cen, M22, and NGC 1851), suggests that the discrete distribution of RGB stars in the $hk$ index might be a universal characteristic of this growing group of peculiar GCs. The planned narrow-band calcium photometry for the Local Group dwarf galaxies would help to establish an empirical connection between these GCs and the primordial building blocks in the hierarchical merging paradigm of galaxy formation.Comment: 4 pages, 4 figures, 1 table, accepted for the publication in ApJ

Exogenous application of plant growth regulators increased the total flavonoid content in Taraxacum officinale Wigg

The effects of plant growth regulators (PGRs) were studied on growth, total flavonoid, gibberellins (GA) and salicylic acid (SA) contents of Taraxacum officinale (dandelion), a widely used medicinal plant in Korea. All the four PGRs used; gibberellic acid (GA3), kinetin (Kn), salicylic acid (SA) and ethephon (2- chloroethylphosphonic acid) were applied at the rates of 0.5 and 1.0 mM. GA3 markedly enhanced fresh shoot weight, while 0.5 mM of kinetin application significantly enhanced dry root mass as compared tocontrol. SA enhanced both shoot and root attributes, while ethephon decreased plant growth. Endogenous bioactive GA1 and GA4 content and SA content enhanced with the application of GA3, SA and kinetin, but declined with ethephon. The flavonoid content of dandelion significantly increased with SA treatment, but was not altered with the application of other PGRs. The current study demonstrated the favorable effect of GA3, kinetin and SA on growth, bioactive GAs, SA and flavonoid contents of dandelion. These investigations offered interesting information as PGRs were never tested for plant growth and development of dandelion. It also reports the presence of both early C-13 hydroxylation and non C-13 hydroxylation pathways of GA biosynthesis in dandelion for the first time

Comparison of Rapid Diagnostic Tests for the Detection of Plasmodium vivax Malaria in South Korea

South Korea is one of many countries with endemic Plasmodium vivax malaria. Here we report the evaluation of four rapid diagnostic tests (RDTs) for diagnosis of this disease. A total of 253 subjects were enrolled in the study. The sensitivities, specificities and agreement frequencies were estimated by comparing the four RDTs against the standard of nested-PCR and microscopic examination. The CareStartTM and SD Bioline had higher test sensitivities (99.4 and 98.8%, respectively) compared with the NanoSign and Asan Easy tests (93.0 and 94.7%, respectively). The CareStartTM and SD Bioline tests could detect P. vivax in samples with parasite densities <150/μl, which was a slightly better performance than the other two RDTs. The quantitative accuracy of the four RDTs was also estimated by comparing results with P. vivax counts from blood samples. Lower test price would result in increased use of these RDTs in the field. The results of this study contribute valuable information that will aid in the selection of a diagnostic method for the detection of malaria

High expression of NR1D1 is associated with good prognosis in triple-negative breast cancer patients treated with chemotherapy

Background Nuclear receptor subfamily 1, group D, member 1 (NR1D1) is a ligand-regulated nuclear receptor and transcriptional factor. Although recent studies have implicated NR1D1 as a regulator of DNA repair and proliferation in breast cancers, its potential as a therapeutic target for breast cancer has not been assessed in terms of clinical outcomes. Thus, this study aims to analyze NR1D1 expression in breast cancer patients and to evaluate its potential prognostic value. Methods NR1D1 expression was analyzed by immunohistochemistry using an anti-NR1D1 antibody in 694 breast cancer samples. Survival analyses were performed using the Kaplan–Meier method with the log-rank test to investigate the association of NR1D1 expression with clinical outcome. Results One hundred thirty-nine of these samples exhibited high NR1D1 expression, mostly in the nucleus of breast cancer cells. NR1D1 expression correlated significantly with histological grade and estrogen receptor status. Overall survival (OS) and disease-free survival (DFS) did not correlate significantly with NR1D1 expression in breast cancer patients regardless of whether they had received chemotherapy. Subgroup analysis performed according to molecular subtype of breast cancer showed a significant influence of high NR1D1 expression on OS (P = 0.002) and DFS (P = 0.007) in patients with triple-negative breast cancer (TNBC) treated with chemotherapy. Conclusions High NR1D1 expression level had a favorable impact on OS and DFS in patients with TNBC treated with chemotherapy. NR1D1 should be investigated further as a possible prognostic marker in TNBC patients receiving chemotherapeutic treatment and as a target in the development of chemotherapeutic approaches to treating TNBC.This work was supported by grants from the National Research Foundation of Korea (2014M3A9D5A01073556, 2017R1A2B3011870, 2018R1A5A2024425, and BK21 Plus program)