2,641 research outputs found
Temperature dependence of Mott transition in VO_2 and programmable critical temperature sensor
The temperature dependence of the Mott metal-insulator transition (MIT) is
studied with a VO_2-based two-terminal device. When a constant voltage is
applied to the device, an abrupt current jump is observed with temperature.
With increasing applied voltages, the transition temperature of the MIT current
jump decreases. We find a monoclinic and electronically correlated metal (MCM)
phase between the abrupt current jump and the structural phase transition
(SPT). After the transition from insulator to metal, a linear increase in
current (or conductivity) is shown with temperature until the current becomes a
constant maximum value above T_{SPT}=68^oC. The SPT is confirmed by micro-Raman
spectroscopy measurements. Optical microscopy analysis reveals the absence of
the local current path in micro scale in the VO_2 device. The current uniformly
flows throughout the surface of the VO_2 film when the MIT occurs. This device
can be used as a programmable critical temperature sensor.Comment: 4 pages, 3 figure
Development of a Semirigid Pavement Incorporating Ultrarapid Hardening Cement and Chemical Admixtures for Cement Grouts
Mechanical tests were carried out to evaluate the influence and effects of fluidity and compressive strength of cement grout on semirigid asphalt pavement. An open graded asphalt skeleton was designed in order to achieve target porosity in the range of 18~22%. In addition, four types of cement grout mixtures were produced with varying mix proportions with ultrarapid hardening cement and chemical admixtures, that is, accelerating and retarding agents. For the semirigid pavement specimens, mechanical experiments to measure properties such as porosity, flexural strength, Marshall stability, and wheel tracking resistance were carried out. The test results demonstrated that the flow time (fluidity) of cement grout is the most significant factor that determines the mechanical properties of semirigid asphalt specimens under constant condition of the open graded asphalt skeleton. For the semirigid pavement mixing proportion in the current study, it is recommended that the porosity of the open graded asphalt skeleton and flow time of cement grout should be 20% and within 12 seconds, respectively
Comparison of Conventional Excision via a Sublabial Approach and Transnasal Marsupialization for the Treatment of Nasolabial Cysts: A Prospective Randomized Study
ObjectivesSurgical excision via a sublabial approach is considered the standard treatment for nasolabial cysts. Although transnasal marsupialization has been proposed as an alternative method, no prospective study has compared the effectiveness of these techniques. We thus compared the surgical procedure, operating time, postoperative pain, complications, and recurrence rate between the two surgical methods.MethodsTwenty patients diagnosed with nasolabial cysts were allocated randomly into two groups according to the surgical technique. In the sublabial approach group, the cysts were excised completely using a sublabial approach, while in the transnasal marsupialization group, the cysts were marsupialized transnasally under the guidance of nasal endoscopes. The pure operating time was measured and postoperative pain was evaluated using a visual analog scale. Complications after the procedure were assessed and recurrence was determined according to the clinical symptoms and postoperative radiologic findings.ResultsThe transnasal marsupialization group had significantly shorter operating times, less postoperative pain, lower complication rates, and shorter duration of side effects than the sublabial approach group. No recurrence occurred in either group after a 1-yr follow-up period.ConclusionAlthough both methods are effective for treating nasolabial cysts, the transnasal marsupialization of nasolabial cysts has many benefits over the conventional sublabial approach. Therefore, we propose that transnasal marsupialization be the treatment of choice for nasolabial cysts
Performance Analysis of CFRP Composite Strips Confined RC Columns under Axial Compression
In an attempt to mitigate the high cost of FRP composite strengthening, an experimental investigation was carried out that sought to achieve efficient and most favorable FRP strengthening using CFRP composite strips. 50 mm wide CFRP composite strips were used in two different spacings (20 mm and 40 mm) to confine columns. The test results of the column confined with smaller spacing (20 mm) showed significant restraint of axial deformation of the column and enhanced the strength capacity to a maximum of 99.20% compared to that of reference column. In contrast, the column confined by strips with larger spacing (40 mm) failed by crushing of concrete alone, which occurred even before the CFRP strips reached their ultimate strain. In addition, the embodied energy that exists in the CFRP strips could not be utilized effectively. The stress and strength enhancement ratio of this present study was compared with the previous research that has been conducted on columns confined with full wrapping. From the obtained results, it is recommended that CFRP strips with a spacing of 20 mm be used to improve the strength capacity of the RC column; in addition, this wrapping technique provides economic benefits compared to a column confined with full wrapping
Mutant pattern of p53 predicts local recurrence and poor survival rate in gastric cancer
Background. TP53 mutation is a poor
prognostic factor for various organ malignancies such as
colorectal cancer, breast cancer, ovarian cancer,
hepatocellular carcinoma, lung adenocarcinoma and
clinical pathologists previously evaluated it using
immunohistochemistry for p53. The clinicopathologic
significance of p53 expression in gastric cancer remains
unclear due to inconsistent classification methods.
Methods. Immunohistochemistry for p53 protein
was performed using tissue microarray blocks generated
from 725 cases of gastric cancer, and p53 expression
was divided into three staining patterns using a semiquantitative ternary classifier: heterogeneous (wild type),
overexpression, and absence (mutant pattern).
Results. Mutant pattern of p53 expression had a
male predominance, greater frequency in cardia/fundus,
higher pT stage, frequent lymph node metastasis, local
recurrence clinically, and more differentiated histology
microscopically compared with wild type. In survival
analysis, p53 mutant pattern was associated with worse
recurrent-free survival and overall survival rates, and
significance was maintained in subgroup analysis of
early versus advanced gastric cancers. In Cox regression
analysis, p53 mutant pattern was a significant predicting
factor for local recurrence (relative risk (RR=4.882,
p<0.001)) and overall survival (RR=2.040, p=0.007).
The p53 mutant pattern remained significant for local
recurrence (RR=2.934, p=0.018) in multivariate
analyses.
Conclusions. Mutant p53 pattern on immunohistochemistry was a significant prognostic factor for
local recurrence and poor overall survival in gastric
cancer
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