A classroom of her own : hegemonic discursive disempowerment of the female progressive educator within higher education

"This dissertation represents a distinct theoretical and pragmatic interrogation into the historically hegemonic discursive disempowerment of women in patriarchal society and institutions of higher education. The axis of which, is the exigencies unique to the female progressive educator (FPE). The FPEs pedagogy is grounded in counterhegemonic consciousness--reframing disempowering practices through education which resists and transforms the ubiquitous residue of overarching patriarchal schema reproduced through hegemonic discourse and culture. In essence she imagines the unimaginable--equity through dialogue among women and men. The framework for exploring these conditions consists of interpersonal communication, rhetorical criticism, sociolinguistic studies, critiques in gender and feminisms, cultural foundations and progressive education. The prologue provides overarching historical antecedents demonstrating the intersection of dominant discourse and the continuum of subordinated lives and locations of women. Chapter I examines institutionally legitimated hegemonic culture and discursive disempowerment of women in society through the powerful triad of church, state and education. Chapter II proposes steps toward realizing discursive empowerment by the FPE through gender holistic discursive communities in dialogue and negotiating Self and Other. Chapter III relates experiential and empirical knowledge specific to the author, a female progressive educator, whose epistemology and pedagogy is predicated on reflexive practice founded in the narrative, identity, hermeneutics of Selfhood and mutuality of Self and Other. Chapter IV moves beyond theoretical frameworks into the domain of a lived pedagogy through the establishment of a national coalition for progressive/antioppressive educators to participate in communities of dialogue and action."--Abstract from author supplied metadata

Developing Customized Employee Engagement Measure in an Indonesian Large Company: Procedure, Validity, and Reliability

Companies have been concerned on measurement and improvement of their employees’ engagement using various conceptual models. Since every company has their own specific vision, mission, and values, customization is needed to measure employee engagement objectively. One of the biggest state-owned company in Indonesia develops a specific model of employee engagement, consisted of 12-dimensions. Those dimensions have been operationalized in order to build a set of questionnaire to measure employee engagement. This study elaborates the procedure taken to create, validate, and testing the reliability of the measure. We administered the newly designed questionnaire (38 items measuring 12-dimensions) as well as Gallup Employee Engagement and Aon Hewitt questionnaires to 869 employees of the company. Significant correlations between measures, significant item-total item correlations, factorial robustness, and discriminative power confirmed the validity of the measure. Internal consistency, test-retest reliability, and Cronbach Alpha confirmed the reliability of the measure. These multiple sources of evidence are discussed

Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer

Background: ErbB2 Receptor Tyrosine Kinase 2 (ErbB2, HER2/Neu) is amplified in breast cancer and associated with poor prognosis. Growing evidence suggests interplay between ErbB2 and insulin-like growth factor (IGF) signaling. For example, ErbB2 inhibitors can block IGF-induced signaling while, conversely, IGF1R inhibitors can inhibit ErbB2 action. ErbB receptors can bind and phosphorylate insulin receptor substrates (IRS) and this may be critical for ErbBmediated anti-estrogen resistance in breast cancer. Herein, we examined crosstalk between ErbB2 and IRSs using cancer cell lines and transgenic mouse models. Methods: MMTV-ErbB2 and MMTV-IRS2 transgenic mice were crossed to create hemizygous MMTV-ErbB2/MMTVIRS2 bigenic mice. Signaling crosstalk between ErbB2 and IRSs was examined in vitro by knockdown or overexpression followed by western blot analysis for downstream signaling intermediates and growth assays. Results: A cross between MMTV-ErbB2 and MMTV-IRS2 mice demonstrated no enhancement of ErbB2 mediated mammary tumorigenesis or metastasis by elevated IRS2. Substantiating this, overexpression or knockdown of IRS1 or IRS2 in MMTV-ErbB2 mammary cancer cell lines had little effect upon ErbB2 signaling. Similar results were obtained in human mammary epithelial cells (MCF10A) and breast cancer cell lines. Conclusion: Despite previous evidence suggesting that ErbB receptors can bind and activate IRSs, our findings indicate that ErbB2 does not cooperate with the IRS pathway in these models to promote mammary tumorigenesis

Determination of the relative economic impact of different molecular-based laboratory algorithms for respiratory viral pathogen detection, including Pandemic (H1N1), using a secure web based platform

<p>Abstract</p> <p>Background</p> <p>During period of crisis, laboratory planners may be faced with a need to make operational and clinical decisions in the face of limited information. To avoid this dilemma, our laboratory utilizes a secure web based platform, Data Integration for Alberta Laboratories (DIAL) to make near real-time decisions.</p> <p>This manuscript utilizes the data collected by DIAL as well as laboratory test cost modeling to identify the relative economic impact of four proposed scenarios of testing for Pandemic H1N1 (2009) and other respiratory viral pathogens.</p> <p>Methods</p> <p>Historical data was collected from the two waves of the pandemic using DIAL. Four proposed molecular testing scenarios were generated: A) Luminex respiratory virus panel (RVP) first with/without US centers for Disease Control Influenza A Matrix gene assay (CDC-M), B) CDC-M first with/without RVP, C) RVP only, and D) CDC-M only. Relative cost estimates of different testing algorithm were generated from a review of historical costs in the lab and were based on 2009 Canadian dollars.</p> <p>Results</p> <p>Scenarios A and B had similar costs when the rate of influenza A was low (< 10%) with higher relative cost in Scenario A with increasing incidence. Scenario A provided more information about mixed respiratory virus infection as compared with Scenario B.</p> <p>Conclusions</p> <p>No one approach is applicable to all conditions. Testing costs will vary depending on the test volume, prevalence of influenza A strains, as well as other circulating viruses and a more costly algorithm involving a combination of different tests may be chosen to ensure that tests results are returned to the clinician in a quicker manner. Costing should not be the only consideration for determination of laboratory algorithms.</p

Documenting the Impact of a Food Pantry Program in Promoting Stability and Independence Among New Haven Residents

An estimated 22% of New Haven residents live with food insecurity. This means more than 1 in 5 residents of New Haven do not have enough food or enough money to buy food. Notably, issues of food insecurity disproportionately affect people of color and those of lower socioeconomic status, therefore exacerbating disparities in health issues related to food insecurity.2 Christian Community Action (CCA) is a local social service organization that provides housing, financial assistance, food, and other support services for low-income New Haven residents. Their food pantry program, which operates on an appointment-only basis, has regularly provided food to over 80 individuals and families in the New Haven area. CCA is interested in identifying areas for improvement to strengthen their service provision and are also collecting data to bolster their advocacy efforts. The objectives of this project are as follows: 1. Assess satisfaction amongst users of a food pantry program in New Haven. 2. Develop a sustainable method for obtaining and incorporating feedback for quality improvement processes. 3. Strengthen understanding of how usage of CCA’s food pantry promotes stability and independence among food pantry users.https://elischolar.library.yale.edu/ysph_pbchrr/1030/thumbnail.jp

Swine Influenza (H3N2) Infection in a Child and Possible Community Transmission, Canada

Seropositivity to the same strain was demonstrated in the child and in multiple other community members